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How a researcher uses Codex and ChatGPT to search for new antimicrobial molecules

OpenAI profiles César de la Fuente's lab using ChatGPT and Codex alongside deep-learning models to accelerate antimicrobial molecule discovery.

OpenAI published a case study on bioengineer César de la Fuente's lab, which uses ChatGPT and Codex for hypothesis brainstorming, code writing, dataset processing, and bridging knowledge gaps across biology, chemistry, and computer science. The lab's deep-learning models scan genome and protein databases for antimicrobial peptide candidates, potentially cutting initial searches from years to hours. Bacterial antimicrobial resistance was associated with about five million deaths in 2021, a toll projected to roughly double by 2050.

OpenAI News · 6d agoAI industry1

Tell HN: OpenAI brings back 5 hour limit for plus and business standard users

OpenAI reinstated a 5-hour usage limit for Plus and Business Standard subscribers, sparking Hacker News debate about subsidized inference pricing and subscription value.

A Hacker News discussion reports that OpenAI has brought back a 5-hour usage limit for Plus and Business Standard users. Commenters debated whether cheap tokens are a subsidized customer acquisition strategy, whether AI companies have sustainable margins on inference, and how switching costs between providers affect dependency. The thread reflects community sentiment on pricing and usage caps rather than an official policy announcement.