Search: “ai explainability”

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HypoEvolve: Genetic Algorithms Enable Multi-Agent LLMs to Discover Scientific Hypotheses

HypoEvolve couples a generational genetic algorithm with specialized LLM agents to generate drug-repurposing hypotheses, beating six baselines on DepMap selectivity (0.171 vs 0.115).

HypoEvolve coordinates specialized LLM agents through a generational genetic algorithm in which scientific judgments and new proposals reshape a hypothesis population. Evaluation centers on drug repurposing, linking mechanistic explanations to target-level biological claims assessed via external measures adapted from DepMap and Open Targets. Across 34 cancer types, HypoEvolve scores highest against six baselines on both measures, with DepMap selectivity of 0.171 versus 0.115 for the strongest baseline, and gains generalize to held-out cancer types.

arXiv cs.AI / cs.LG / cs.CLSep 14, 17:44 UTC · 2d agoAI research 2 sources1

Can Skills Learned in Games Transfer to Real-World Work?

Good Start Labs trains models in strategy games like 1830 and Diplomacy, showing terminal-agent training transfers to financial research benchmarks.

Good Start Labs, spun out of Every with $3.6M from General Catalyst and Inovia, trains AI models in verifiable strategy games. A 30B model trained as a multi-turn terminal agent in 1830: The Game of Railroads and Robber Barons improved Finance-Agent benchmark performance, while single-turn QA training did not transfer. The founders also co-authored COS-PLAY, a paper on co-evolving LLM decision and skill-bank agents for long-horizon tasks.

Latent SpaceSep 15, 20:11 UTC · 1d agoAI research

Stanford Researchers Release Paper2Agent: Turning Research Papers Into AI Agents That Reproduce Results and Run on New Data

Stanford researchers released Paper2Agent, a Nature-published pipeline that turns research papers into MCP servers agents can execute.

A Stanford team led by Jiacheng Miao and James Zou published Paper2Agent in Nature on 16 September 2026. Built on Claude Code's agent SDK, it converts a paper and its codebase into a Model Context Protocol server with validated tools, resources, and prompts. In benchmarks, the AlphaGenome agent built 22 tools in about 45 minutes for US$14, scored 100% on 15 novel queries versus 78.7% for Claude Code with repository access, and cut median runtime 1.9x. In scale tests, 74 of 100 bioRxiv papers were converted and 593 of 599 proposed tools passed validation.

MarkTechPostSep 16, 21:59 UTC · 15h agoAI research1

Nunchux AI Introduces VC-Attention: A Training-Free Low-Bit Attention Kernel That Speeds Up Video Diffusion Transformers

Nunchux AI introduces VC-Attention, a training-free low-bit attention kernel that speeds up video diffusion transformers up to 3.58x.

Nunchux AI unveiled VC-Attention, a training-free attention kernel for video Diffusion Transformers combining V-Smooth (k-means value-token grouping with block-mean residual quantization) and ExpCast-FP8 (single multiply-add softmax exponentiation). Benchmarks on Wan2.2-T2V-A14B, LongCat-Video, HunyuanVideo-1.5, and MiniMax-H3 show 1.59x attention speedup on B200 at 8-bit and 3.58x on RTX 5090 at 4-bit, with end-to-end gains up to 1.70x. It beats SageAttention2 by 2.3 dB PSNR on Wan2.2 at 8-bit and SageAttention3 by up to 3.6 dB at 4-bit. No public kernel release yet; a proprietary extension runs in Nunchux's stack.

MarkTechPost00:45 UTC · 12h agoAI research 2 sources1

Agent Harness vs Agent Framework vs MCP: Which Layer Owns the Loop, State, Tools, Permissions, and Recovery

Architecture explainer separates agent harnesses, frameworks, and MCP by which layer owns the loop, state, permissions, and recovery.

The article distinguishes agent harnesses (OpenAI Codex, Claude Agent SDK), which own the execution loop, sandbox, permission model, and recovery; frameworks (LangGraph, OpenAI Agents SDK, Microsoft Agent Framework), which supply composable primitives; and MCP, a stateless JSON-RPC wire protocol governed by the Linux Foundation's Agentic AI Foundation since December 2025. An ownership matrix maps the execution loop, state, tool transport, permissions, recovery, sandboxing, and multi-agent orchestration to each layer. The 2026-07-28 MCP specification made the protocol fully stateless, retiring the initialize handshake and session headers.

MarkTechPostSep 14, 21:54 UTC · 2d agoAI research1

Google Research Introduces Retrieve-for-Train (R4T): An RL-Compiled Diffusion Retriever for 12× to 20× Faster Query Fan-Out

Google Research introduced R4T, an RL-trained fan-out pipeline distilled into a 53.9M-parameter diffusion retriever achieving 12x-20x faster query fan-out.

Google Research introduced Retrieve-for-Train (R4T), which trains a fan-out language model with GRPO plus soft PPO regularization, then distills query fan-out into a 53.9M-parameter diffusion transformer that generates all retrieval embeddings in a single non-autoregressive pass. A three-term reward (groundedness 0.6, diversity 0.2 via Vendi Score, alignment 0.2) prevents paraphrastic collapse and reward hacking during training. On the Polyvore dataset, Gemma3-4B R4T-FOLM averaged 49.1 versus 40.9 for Best-of-N, and the diffusion retriever cut fan-out latency from 1.46s to 0.07s at batch size 8, a consistent 12x-20x speedup over autoregressive methods.

MarkTechPost06:19 UTC · 7h agoAI research1