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AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

Google DeepMind released AlphaGenome Atlas, a free 1-petabyte platform predicting the molecular effects of all ~9 billion possible single-letter DNA variants.

Google DeepMind introduced AlphaGenome Atlas, containing precomputed predictions for the effects of roughly 9 billion single-nucleotide variants across the human genome, spanning hundreds of human and mouse cell types. The 1-petabyte dataset is more than 30 times larger than the AlphaFold Database and includes an AlphaGenome Variant Impact (AVI) score combining AlphaGenome and AlphaMissense predictions for both coding and non-coding regions. External collaborators have already used it to identify and experimentally verify variants in unsolved rare disease research. It is available via a free web portal, the AlphaGenome API, and as a skill in Google Antigravity.

Google DeepMindSep 8, 14:00 UTC · 8d agoAI research 2 sources

Axis Robotics Releases AXIS: A Browser-Based Data Engine With 207 Robot Manipulation Tasks and 50,129 Trajectories

Axis Robotics and academic partners released AXIS, a browser-based teleoperation system yielding 207 manipulation tasks and 50,129 trajectories that lifts pi0.5 to 88.8 on LIBERO-Plus.

A team from Axis Robotics, UC Berkeley, Georgia Tech, and NTU introduced AXIS, a browser-based data engine where contributors teleoperate a simulated Franka Research 3 in a MuJoCo WebAssembly frontend while GPU backends handle task generation, training, and evaluation. The released snapshot holds 207 tasks, 50,129 episodes, and 60K+ task or scene variants from more than 70,000 community contributors. Continual pretraining of pi0.5 on AXIS data raises LIBERO-Plus performance from 83.9 to 88.8, versus 57.5 for a volume-matched RoboCasa365 control; the 2.36 TB dataset is gated for non-commercial academic use.

MarkTechPostSep 7, 18:38 UTC · 9d agoAI research

Google DeepMind Releases AlphaGenome Atlas

Google DeepMind released AlphaGenome Atlas, a 1-petabyte database pre-computing effects of all 9 billion single-nucleotide variants in the human genome, with a unified AVI score.

Google DeepMind launched AlphaGenome Atlas, a database that predicts the regulatory impact of every possible single nucleotide variant across the roughly 3 billion base pairs of the human genome, yielding a 1-petabyte dataset. It introduces the AlphaGenome Variant Impact (AVI) score, combining coding and non-coding predictions for rapid variant prioritization. Broad Institute researchers used it to support solving an unsolved rare disease case via a predicted DNM1 splice variant, and analysis of 54,000+ UK Biobank participants uncovered 22% more non-coding genetic associations, including 19 regions linked to BMI. The Atlas is available through a no-code web portal.

Hacker News · AISep 8, 14:55 UTC · 8d agoAI research HN 44↑ · 4 comments