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AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

Google DeepMind released AlphaGenome Atlas, a free 1-petabyte platform predicting the molecular effects of all ~9 billion possible single-letter DNA variants.

Google DeepMind introduced AlphaGenome Atlas, containing precomputed predictions for the effects of roughly 9 billion single-nucleotide variants across the human genome, spanning hundreds of human and mouse cell types. The 1-petabyte dataset is more than 30 times larger than the AlphaFold Database and includes an AlphaGenome Variant Impact (AVI) score combining AlphaGenome and AlphaMissense predictions for both coding and non-coding regions. External collaborators have already used it to identify and experimentally verify variants in unsolved rare disease research. It is available via a free web portal, the AlphaGenome API, and as a skill in Google Antigravity.

Google DeepMindSep 8, 14:00 UTC · 8d agoAI research 2 sources

Hierarchical NeRF with JAX3D for Volumetric Rendering, Novel-View Synthesis, and 3D Reconstruction

MarkTechPost tutorial implements a hierarchical NeRF in JAX using jax3d volume-rendering primitives for novel-view synthesis and 3D reconstruction.

The tutorial builds an end-to-end hierarchical Neural Radiance Field using JAX, Flax, Optax, and jax3d's volume-rendering functions (sample_along_rays, volume_rendering, sample_piecewise_constant_pdf). It implements positional encoding, skip connections, separate coarse and fine networks, and view-direction conditioning with hierarchical importance sampling. Training uses JAX JIT compilation, Adam optimization, exponential learning-rate decay, and gradient clipping. Evaluation covers PSNR, depth and opacity visualization, 360-degree rendering, and marching-cubes geometry extraction.

MarkTechPostSep 13, 19:46 UTC · 2d agoAI research