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Google DeepMind Releases AlphaGenome Atlas With Precomputed Molecular Effect Predictions and AVI Scores for 9 Billion Human DNA Variants

Google DeepMind launched AlphaGenome Atlas, precomputing molecular effect predictions and AVI impact scores for ~9 billion human single-nucleotide variants in a 1-petabyte catalogue.

Google DeepMind released AlphaGenome Atlas, a 1-petabyte catalogue of precomputed molecular effect predictions for roughly 9 billion possible single-nucleotide variants in the human genome. It introduces the AlphaGenome Variant Impact (AVI) score, combining AlphaGenome regulatory predictions with AlphaMissense, plus per-variant feature attributions and over 2,500 recurrent DNA sequence motifs. DeepMind reports best-in-class AVI performance on variant pathogenicity and rare disease benchmarks. Early users at the Broad Institute, University of Exeter, and Stowers Institute demonstrated rare-disease variant reprioritization and 22% more non-coding associations across 54,000+ UK Biobank genomes.

MarkTechPost · 8d agoAI research2

Stanford Researchers Release Paper2Agent: Turning Research Papers Into AI Agents That Reproduce Results and Run on New Data

Stanford researchers released Paper2Agent, a Nature-published pipeline that turns research papers into MCP servers agents can execute.

A Stanford team led by Jiacheng Miao and James Zou published Paper2Agent in Nature on 16 September 2026. Built on Claude Code's agent SDK, it converts a paper and its codebase into a Model Context Protocol server with validated tools, resources, and prompts. In benchmarks, the AlphaGenome agent built 22 tools in about 45 minutes for US$14, scored 100% on 15 novel queries versus 78.7% for Claude Code with repository access, and cut median runtime 1.9x. In scale tests, 74 of 100 bioRxiv papers were converted and 593 of 599 proposed tools passed validation.

MarkTechPost · 2h agoAI research

Hierarchical NeRF with JAX3D for Volumetric Rendering, Novel-View Synthesis, and 3D Reconstruction

MarkTechPost tutorial implements a hierarchical NeRF in JAX using jax3d volume-rendering primitives for novel-view synthesis and 3D reconstruction.

The tutorial builds an end-to-end hierarchical Neural Radiance Field using JAX, Flax, Optax, and jax3d's volume-rendering functions (sample_along_rays, volume_rendering, sample_piecewise_constant_pdf). It implements positional encoding, skip connections, separate coarse and fine networks, and view-direction conditioning with hierarchical importance sampling. Training uses JAX JIT compilation, Adam optimization, exponential learning-rate decay, and gradient clipping. Evaluation covers PSNR, depth and opacity visualization, 360-degree rendering, and marching-cubes geometry extraction.

MarkTechPost · 3d agoAI research

H Company Releases NeoMME: A Family of 260M and 800M Single-Tower Multimodal Encoders That Drop the Vision Tower and Causal Decoder

H Company released NeoMME, 260M/800M single-tower multimodal encoders matching 3.75B ColQwen2.5 on ViDoRe v3 while being 14.4x smaller, under Apache 2.0.

H Company released NeoMME, a family of 262,937,906- and 793,715,032-parameter bidirectional encoders that process text and raw 32x32 image patches in a single tower, pretrained via masked diffusion and released under Apache 2.0 with day-zero Hugging Face Transformers support. NeoMME-Retriever-260M reaches 0.523 nDCG@10 on ViDoRe v3, matching 3.75B-parameter ColQwen2.5 while being 14.4x smaller; the 800M model scores 0.556. Hierarchical token pooling with int8 and binary quantization shrinks late-interaction indexes from roughly 1.5 MB to 6 kB per page while retaining 95.19% of nDCG@10; text-only BEIR retrieval remains a weak spot.

MarkTechPost · 10d agoAI research

Meta FAIR Introduces AI Research Preference Models (RPMs): Ranking ML Experiments Before Spending GPU Hours

Meta FAIR, Oxford and UCL introduce Research Preference Models that rank unexecuted ML experiments, lifting AIRS-Bench scores from 0.684 to 0.729 and cutting compute ~1.6×.

Researchers from Meta FAIR, Oxford, and UCL introduce Research Preference Models (RPMs), which use frozen pretrained LLMs (Qwen3.6-27B backbone, no fine-tuning) to rank unexecuted experiment candidates and execute only the winner of a pairwise knockout tournament. Two variants shipped: an inference-only LLM-as-a-judge and an agentic variant that runs small pilot experiments in an H200 sandbox. On AIRS-Bench (20 tasks, 24 hours on one H200, 10 seeds), scores rise from 0.684 (random) to 0.711 and 0.729 versus a 0.748 validation oracle, and both variants reach the baseline's 24-hour score in roughly 15 hours. The team reports new SOTA on WinoGrande (94.1% with Agentic RPM) and SVAMP (95.7% with inference-only).

MarkTechPost · 10d agoAI research