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Reporting Practice Matters: The Impact of Reference Choice on Chest X-ray Report Evaluation

Study shows radiology reporting-style variations in reference reports can flip rankings of chest X-ray report generation models; releases MIMIC-CXR-Ext-ReRef dataset.

The paper quantifies how variations in radiologists' reporting practices distort evaluation of radiology report generation (RRG) models, introducing a radiologist-informed taxonomy and the ReRef method for rewriting reference reports while preserving clinical meaning. On MIMIC-CXR with RadCliQ-v1, condensing normal-findings discussion caused Libra to drop from first to second while CheXOne rose from third to first among nine models. The authors release MIMIC-CXR-Ext-ReRef, a radiologist-validated dataset of 120 original/alternative reference pairs, arguing metrics conflate clinical correctness with stylistic conformity.

arXiv cs.AI / cs.LG / cs.CL · 18h agoAI research

ModaLens: Measuring Image Sensitivity in Report-Conditioned Medical VLMs

ModaLens image-swap audit shows report availability cuts MedGemma-27B image sensitivity on MIMIC-CXR from 20.94% to 4.26% answer changes.

ModaLens is a paired image-swap audit measuring how report availability affects image sensitivity in report-conditioned medical VLMs. On MedGemma-27B across 3,199 paired MIMIC-CXR cases from 293 patients (14 questions per case), generated answers changed on 4.26% of image-swap trials with the report versus 20.94% without it, a 16.7-point paired difference (95% CI 15.6-17.7). The original prompt with a lowercase first-token readout gave 4.70% versus 17.07%, and the direction replicated in two further model lineages. Labels derived from reports limit conclusions about visual correctness; code, prompts, and run records are publicly released.

Hugging Face daily papers · 3d agoAI research

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

Researchers introduce NOAH, a generative time-aware transformer trained on 559 million MIMIC clinical events to model and forecast patient trajectories.

NOAH is a task-agnostic, time-aware generative transformer designed to represent and forecast the full multimodal patient journey across medical images, time-series signals, categorical events, and clinical text. It was trained on over 559 million clinical events from 431,000 hospital visits covering 299,000 patients in the MIMIC dataset family. The architecture combines bidirectional time integration with a variational latent space to capture continuous patient state evolution and clinical stochasticity. NOAH supports autoregressive forecasting with time control, zero-shot classification, and counterfactual intervention simulation, with evaluations on 15 ICD chapters, 29 comorbidities, and time-to-event prediction.

arXiv cs.AI / cs.LG / cs.CL · 8d agoAI research2

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

Researchers introduce NOAH, a time-aware generative transformer trained on 559 million MIMIC clinical events to forecast multimodal patient trajectories.

NOAH is a task-agnostic, time-aware generative transformer trained on over 559 million clinical events from 431,000 hospital visits by 299,000 patients across the MIMIC dataset family. It uses bidirectional time integration and a variational latent space to model the stochastic evolution of patient states, natively processing medical images, time-series signals, categorical events, and structured or unstructured clinical records. The model supports autoregressive forecasting with optional time control, zero-shot classification, and counterfactual intervention simulation, with strong probing performance across clinical outcomes, 15 ICD chapters, and 29 comorbidities.

Hugging Face daily papers · 9d agoAI research1

Before You Poll with LLMs: A Deliberative Diagnostic Framework

Deliberative diagnostic shows all five tested frontier LLMs misrepresent human belief shifts after arguments, with GPT-5.1 reversing on outgroup questions.

The Deliberative Polling Diagnostic Framework compares human and LLM persona belief shifts after identical informational interventions, using data from America in One Room (526 personas, 72 questions). All five frontier models tested failed uniquely: GPT-5.1 exhibited partisan reversal (80% on outgroup vs 26% on policy questions), Gemini 2.0 Flash, Claude Sonnet 4.5 and Llama 3.3 70B overshot at 5-7x human magnitude, and DeepSeek V3 showed near-zero change (rigidity). The authors term the underlying signature 'self-sycophancy', conformity to the model's internal persona stereotype rather than reasoning from provided information.

arXiv cs.AI / cs.LG / cs.CL · 2d agoAI research

Google DeepMind Releases AlphaGenome Atlas With Precomputed Molecular Effect Predictions and AVI Scores for 9 Billion Human DNA Variants

Google DeepMind launched AlphaGenome Atlas, precomputing molecular effect predictions and AVI impact scores for ~9 billion human single-nucleotide variants in a 1-petabyte catalogue.

Google DeepMind released AlphaGenome Atlas, a 1-petabyte catalogue of precomputed molecular effect predictions for roughly 9 billion possible single-nucleotide variants in the human genome. It introduces the AlphaGenome Variant Impact (AVI) score, combining AlphaGenome regulatory predictions with AlphaMissense, plus per-variant feature attributions and over 2,500 recurrent DNA sequence motifs. DeepMind reports best-in-class AVI performance on variant pathogenicity and rare disease benchmarks. Early users at the Broad Institute, University of Exeter, and Stowers Institute demonstrated rare-disease variant reprioritization and 22% more non-coding associations across 54,000+ UK Biobank genomes.

MarkTechPost · 8d agoAI research2