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Speculative Decoding in vLLM on AMD GPUs

vLLM benchmarks speculative decoding on AMD Instinct MI300X and MI355X GPUs across five drafting methods including EAGLE-3 and native MTP.

The vLLM project documents draft-and-verify speculative decoding support for AMD GPUs via ROCm, comparing native MTP, Gemma 4 MTP, EAGLE-3, DFlash, and DSpark drafting approaches. Output-token throughput effects varied with drafting method, proposal length, model family, draft checkpoint, workload, and acceptance behavior. The post also covers how to enable each method plus practical tuning and observability considerations.

Hacker News · AI · 9d agoAI tools & infraHN 141↑ · 52 comments1

NVIDIA Details BioNeMo Inference Runtime (BioIR): 2.90x Higher Boltz-2 Folding Throughput and 58.5K Residues per GPU-Hour on 8xH100

NVIDIA released BioNeMo Inference Runtime (BioIR), an open-source PyTorch-compatible library delivering 2.90x higher Boltz-2 protein-folding throughput on 8xH100 GPUs.

NVIDIA detailed BioIR, a Python library that accelerates Boltz-2, OpenFold2, and OpenFold3 structure-prediction inference on NVIDIA GPUs while preserving standard PyTorch workflows. On a matched benchmark of 1,000 human dimers on 8xH100 80GB GPUs, BioIR delivered 58.5K folded residues per GPU-hour versus 20.2K for a torch.compile baseline, a 2.90x throughput gain. BioIR already powered the AlphaFold Database expansion, generating about 31 million candidate complexes across 4,777 proteomes, with 1.81 million released as high-confidence predictions. Extrapolated to 1 million targets, estimated folding energy drops from 35 MWh to 11 MWh at 8-GPU TDP equivalents.

MarkTechPost · 5d agoAI tools & infra1

Google Open-Sources Mantis: A Modular Skills Toolkit That Lets Coding Agents Find, Reproduce and Patch Vulnerabilities

Google open-sourced Mantis, an Apache-2.0 modular skills toolkit that lets AI coding agents find, reproduce, and patch vulnerabilities with sandboxed verification.

Google released Mantis on GitHub under Apache 2.0 as a stack-agnostic set of slash-command skills that chain through the full vulnerability lifecycle: mining version history, building threat models, filtering findings, reproducing bugs in gVisor or network-disabled VMs, assembling exploit chains, patching, and scoring residual risk from 1 to 10. It runs with Gemini CLI, Antigravity CLI, the Google ADK, or comparable agent frameworks, and a supervisor skill (/mantis-meta-agent) can drive the whole loop. Google says the design targets the sub-7 percent true-positive rate of naive AI code scanning, and that its hierarchical summary tree cuts token overhead by over 85 percent. The toolkit is deployable for local and internal evaluation but not yet recommended for production.

MarkTechPost · 6d agoAI tools & infra