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10 most critical LLM vulnerabilities

OWASP updated its Top 10 LLM application vulnerabilities, ranking prompt injection first and elevating excessive agency to third amid agentic adoption.

OWASP refreshed its Top 10 list of critical vulnerabilities in LLM applications, for the first time incorporating real-world incident data alongside expert voting. Prompt injection and sensitive information disclosure remain first and second, while excessive agency jumped from sixth to third as agentic systems that call APIs and execute code proliferate. Unbounded consumption of AI resources rose in prominence, while improper output handling dropped to the bottom as output sanitization becomes widespread. The list includes remediation guidance such as strict output schemas, human-in-the-loop approvals, and least-privilege credentials held in application code.

CSO Online · 7d agoAI safety & security

AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

Google DeepMind released AlphaGenome Atlas, a free 1-petabyte platform predicting the molecular effects of all ~9 billion possible single-letter DNA variants.

Google DeepMind introduced AlphaGenome Atlas, containing precomputed predictions for the effects of roughly 9 billion single-nucleotide variants across the human genome, spanning hundreds of human and mouse cell types. The 1-petabyte dataset is more than 30 times larger than the AlphaFold Database and includes an AlphaGenome Variant Impact (AVI) score combining AlphaGenome and AlphaMissense predictions for both coding and non-coding regions. External collaborators have already used it to identify and experimentally verify variants in unsolved rare disease research. It is available via a free web portal, the AlphaGenome API, and as a skill in Google Antigravity.

Google DeepMind · 8d agoAI research 2 sources