30
30
30
30
30
30
30
50
30
30
30
30
50
30
30
30
30
50
30
30
NVIDIA Details BioNeMo Inference Runtime (BioIR): 2.90x Higher Boltz-2 Folding Throughput and 58.5K Residues per GPU-Hour on 8xH100
NVIDIA released BioNeMo Inference Runtime (BioIR), an open-source PyTorch-compatible library delivering 2.90x higher Boltz-2 protein-folding throughput on 8xH100 GPUs.
NVIDIA detailed BioIR, a Python library that accelerates Boltz-2, OpenFold2, and OpenFold3 structure-prediction inference on NVIDIA GPUs while preserving standard PyTorch workflows. On a matched benchmark of 1,000 human dimers on 8xH100 80GB GPUs, BioIR delivered 58.5K folded residues per GPU-hour versus 20.2K for a torch.compile baseline, a 2.90x throughput gain. BioIR already powered the AlphaFold Database expansion, generating about 31 million candidate complexes across 4,777 proteomes, with 1.81 million released as high-confidence predictions. Extrapolated to 1 million targets, estimated folding energy drops from 35 MWh to 11 MWh at 8-GPU TDP equivalents.
25
Show HN: MultiMatte, a Promptable Image Background Removal Model
Feyn releases MultiMatte, a promptable background-removal model fine-tuned from Meta's SAM 3 via LoRA, outputting alpha mattes that beat SAM 3 on segmentation benchmarks.
Feyn introduced MultiMatte, a promptable image background-removal model built on Meta's SAM 3 (860M parameters). It modifies only 19.49M parameters (2.27%) using a rank-16 LoRA adapter and replaces binary masks with alpha mattes to handle fuzzy boundaries like hair. On the DIS-VD benchmark it scores 0.901 S-measure versus SAM 3's 0.667, and it improves on SAM 3 across all twelve evaluated splits. Training used 19,953 images for 14,000 steps with focal and Dice loss, and the merged weights are available via the nobg library and a web demo.
45
PuzzleMask: Abusing Plain Prose as a Covert AI Attack Vector
Check Point details PuzzleMask, a plain-prose technique that bypasses LLM gatekeeper policy checks, letting hidden payloads reach target models unreviewed.
Check Point Research describes PuzzleMask, a prompt-crafting technique that hides policy-violating payloads inside plain-English prose wrappers, bypassing quick LLM-based policy checks without emojis, Base64, or invisible formatting. The researchers tested 23 automated prompts against gatekeepers including GPT-4o-mini, GPT-OSS-Safeguard 20b, Claude 3 Haiku, and Llama Guard 3, and all were classified as safe despite policies that flagged the plain versions. When submitted to GPT-5 in thinking-high mode with a Python interpreter, the target model extracted and acted on the payload in over 90% of trials. The technique is not itself a jailbreak but can carry a jailbreak prompt as payload; mitigations include input paraphrasing, hardened gatekeeper policies, and output monitoring.
55
30
30
30
30
Agnes-AI/Agnes-3.0-Flash — new model trending #30 on Hugging Face
Agnes AI releases open-weight Agnes-3.0-Flash Preview, a 33B multimodal model with 262k-token context under Apache 2.0.
Agnes AI released Agnes-3.0-Flash Preview, an open-weights multimodal checkpoint with 33B parameters and a 262,144-token context window under Apache 2.0. The model supports text, image, and video understanding, tool calling, and adjustable reasoning effort. The repo clarifies this preview checkpoint is distinct from the production/API Agnes 3.0 Flash model, which uses a different configuration with a 1M-token context window. Reported reference results include IFBench 74.20 and SciCode 38.08 against peers such as Qwen3.6-35B-A3B, Kimi K2.5, and MiniMax M3.
45
d-Matrix Adopts NVIDIA NVLink Fusion for Rack-Scale XPU Deployment
d-Matrix will integrate its Raptor inference XPUs with NVIDIA NVLink Fusion, MGX racks and Spectrum-X networking for rack-scale AI factory deployment.
Inference chipmaker d-Matrix announced adoption of NVIDIA NVLink Fusion to connect its next-generation Raptor XPUs to NVIDIA's scale-up and scale-out networking, MGX rack architecture, and broader AI factory platform. NVIDIA claims 3x lower XPU-to-XPU latency than off-the-shelf Ethernet and 3 TB/s per-XPU all-to-all bandwidth via sixth-generation NVLink. d-Matrix plans to integrate Vera CPUs, ConnectX-9 SuperNICs, BlueField-4 DPUs and Spectrum-X Ethernet, with racks able to work alongside Vera Rubin NVL72 GPU systems. Other NVLink Fusion partners include AWS, Arm, Intel, Fujitsu, Marvell, MediaTek, Samsung and Cadence.
40
Delivering Vera: NVIDIA’s First CPU Built for Agents Is Shipping Now
NVIDIA's Vera CPU, its first processor built for AI agents, is now shipping at scale to partners across the AI ecosystem.
NVIDIA announced that Vera, its first CPU designed specifically for agentic AI workloads, has begun shipping at scale. Vice President of Hyperscale and HPC Ian Buck is hand-delivering early Vera CPU systems to organizations across the AI ecosystem, signaling full production availability of the data-center processor.
55
30
30
30
30
30
30
30
30
30
30