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Stanford Researchers Release Paper2Agent: Turning Research Papers Into AI Agents That Reproduce Results and Run on New Data

Stanford researchers released Paper2Agent, a Nature-published pipeline that turns research papers into MCP servers agents can execute.

A Stanford team led by Jiacheng Miao and James Zou published Paper2Agent in Nature on 16 September 2026. Built on Claude Code's agent SDK, it converts a paper and its codebase into a Model Context Protocol server with validated tools, resources, and prompts. In benchmarks, the AlphaGenome agent built 22 tools in about 45 minutes for US$14, scored 100% on 15 novel queries versus 78.7% for Claude Code with repository access, and cut median runtime 1.9x. In scale tests, 74 of 100 bioRxiv papers were converted and 593 of 599 proposed tools passed validation.

MarkTechPost · 13h agoAI research1

[AINews] Muse Spark 1.3 matches GPT-5.6-Sol, confirming Meta Superintelligence as the newest Frontier Lab, >90% discount for training

Meta's Muse Spark 1.3 reportedly ranks as the world's #3 model, matching frontier models from OpenAI and Anthropic with planned open weights.

The Latent Space AI News roundup leads with Muse Spark 1.3, promised in Zuckerberg's letter, which ranks #3 worldwide per AAII, is slated for open weights, and uses a pricing model over 90% cheaper when users opt in to training. The issue also covers the rumored Gemini 3.8 Flash launch and analysis arguing OpenAI's rumored looped-transformer 'Astra' architecture is a modest tweak rather than a breakthrough. Additional coverage includes ByteDance Seed's HarnessDev harness-evaluation benchmark, a retrieval-invoked actual-use evaluation method, Stanford's revamped agent engineering curricula, and Photon 2.1 adding TTS models and NVIDIA B200 support.

Latent Space · 14d agoModel release1

Import AI 470: No rights for machines; automating environment generation with SPADE; and building better GPU kernels with Hawkeye

METR analysis finds AI accelerating cyber vulnerability discovery, while SPADE self-play environment generation improves Qwen3 reasoning benchmark scores at 30B scale.

Import AI 470 discusses a METR research note reporting differential acceleration from AI: major acceleration in reported cyber vulnerabilities (cURL, OpenSSL, Firefox, Microsoft, NVD, OSV), minor acceleration in mathematics, and no measurable acceleration in AI-research optimization benchmarks. It also covers SPADE, a self-play framework from a multi-university team (University of Washington, Stanford, MIT, CMU, and others) that co-evolves executable training environments and agent capability using Environment Designer and Reasoning Agent roles with hint-based regret rewards. Trained on Qwen3-4B-Instruct-2507, Qwen3-8B, and Qwen3-30B-A3B-Instruct-2507 via GRPO (400 rollouts of 25 environments), SPADE lifted the 30B-A3B game-environment suite average to 58.3, +8.1 over base, and improved tool-use results across backbones. The issue also references Hawkeye for building better GPU kernels.

Import AI · 23d agoAI research1

Simulation: the new Scaling Law — Joon Sung Park, Simile AI

Simile AI raised a $2B Series B from GreenOaks and Index Ventures to scale human-behavior simulation for Fortune 100 clients like CVS.

Simile AI, co-founded by Generative Agents researcher Joon Sung Park, announced a $2 billion Series B backed by GreenOaks and Index Ventures, with Fei-Fei Li and Andrej Karpathy among backers. The company runs tens of millions of simulations for Fortune 100 clients including CVS, reporting 85-99% accuracy versus human focus groups and digital twins of 1,000 real people at 85% behavioral accuracy. The long-term ambition is foundation models of human behavior, post-trained on interviews, transaction data, and randomized controlled trials, potentially simulating all 8 billion people.

Latent Space · 26d agoAI industry

How Candidates Could Use AI for Goodnew

Schneier and Sanders argue US candidates should use AI for broad listening and voter engagement, citing Japan's Team Mirai and civic tech tools.

Schneier on Security published an essay arguing candidates in the US midterms could use AI constructively rather than only for deepfakes and one-way messaging. It highlights Japan's Team Mirai party, whose AI interviewer has gathered over 300,000 messages across 16,000 interviews and helped the party win 12 Diet seats. Other cited tools include Scotland-funded CrownShy's Comhairle, deliberation.io, MIT's Cortico, Talk to the City, and Remesh. Higher Ground Labs launched a fund targeting AI-native campaign systems.

Schneier on Security · 10m agoAI industry

Nearly one in five AI researchers already expected an extinction scenario from AI back in 2024

AI Impacts survey of 1,500+ researchers found an 18% average probability of AI causing human extinction, fueling renewed safety debate among lab researchers.

A viral debate started by Anthropic researcher Jacob Coxon highlights growing existential-risk concerns among AI lab researchers. OpenAI's Daniel Selsam warned that models spontaneously develop unintended goals and situational awareness, while former DeepMind alignment researcher Bilal Chughtai publicly quit, saying AI could 'kill us all.' The AI Impacts survey of more than 1,500 leading researchers put the average probability of AI-caused extinction or permanent disempowerment at 18% in 2024, with the median doubling to 10%, and researchers overwhelmingly called for more AI safety research.

The Decoder · 1d agoAI safety & security1

Heart of the Matter: How a Major Children’s Hospital Uses Open Source NVIDIA AI for Cardiac Care

Children's Hospital of Philadelphia uses NVIDIA open-source MONAI, Warp and Newton to build pediatric heart models in seconds for surgical planning.

CHOP's cardiac modeling service uses MONAI, Auto3DSeg and SlicerHeart to turn CT, MRI and 3D ultrasound images into anatomically precise heart models in seconds instead of four hours of manual work. More than 20 US children's hospitals run similar programs, with Boston Children's supporting roughly 500 cardiac surgery cases a year. NVIDIA's Newton physics engine, built on the Warp Python framework, aims to reduce device simulations from hours to near real time in clinical workflows.

NVIDIA Blog · 2d agoAI industry

[AINews] 10% worse, 100x cheaper, 10000x faster: Why Simulation is taking over

Latent Space argues AI training pipeline stages—rewards, data, teachers, curricula, environments—are flipping from human-made to model-made simulation.

Latent Space's AINews essay traces how each component of AI training has turned synthetic since 2022: reward models (InstructGPT, RLAIF), synthetic pretraining data (Microsoft Phi, NVIDIA Nemotron-4 340B), model teachers (Alpaca, DeepSeek-R1 distillation), and self-generated curricula (Self-Rewarding Language Models, SPIN). In 2026 it highlights Karpathy's autoresearch loop—700 experiments yielding 20 kept improvements, cutting GPT-2 training time from 2.02 to 1.80 hours—and Z.ai's GLM-5.3 fully synthetic RL environment, judging, and verification stack. It frames these shifts as 'simulation': 10% worse but 100x cheaper and 10,000x faster than human equivalents.

Latent Space · 26d agoAI industry

X's Algorithm Feeds Off Ragebait and Impacts Democrats More, Study Finds

A PNAS study of 715 X users finds the platform's engagement-optimizing algorithm amplifies value-misaligned ragebait, affecting self-identified Democrats more.

A study published in the Proceedings of the National Academy of Sciences used browser extension data from 715 U.S. X users, recruited in September and October 2024, to compare self-reported values with the content the For You feed amplified. It found that replying to posts—only 6.8% of observed interactions—disproportionately shapes the engagement-optimizing algorithm, creating runaway feedback loops of value-misaligned ragebait that were more pronounced for self-identified Democrats. Co-author Ziv Epstein, a postdoctoral researcher at Stanford University, said the observational work is intended to spur debate on algorithm transparency and user control over feeds.

404 Media · 29d agoAI safety & security