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Discovery Foundation Models: Toward Open-Ended Discovery Intelligence

Proposes Discovery Foundation Models that participate in creating new problems and knowledge, instantiated in Zetema and the GALILEO therapeutic-discovery system.

The paper formulates Discovery Foundation Models (DFMs) as general-purpose systems for open-ended discovery, supporting seven coupled capabilities from problem discovery through evidence-grounded revision and continual improvement. It instantiates the framework with Zetema, combining explicit research-state dynamics, verification gating, external grounding, and cross-task Discovery Skill evolution. GALILEO, a real therapeutic-discovery system, closes the loop between Dry-Lab reasoning, robotic and hands-on Wet-Lab experimentation, and iterative hypothesis revision. The authors also define process-centered evaluation so discovery behavior can be trained and measured beyond final answers.

ScienceBuddy: Recursive-in-Recursive Self-Improvement for Interactive Scientific Agents

ScienceBuddy released: interactive scientific agent workspace coupling harness evolution with model reinforcement learning for continual self-improvement across four scientific task families.

ScienceBuddy is an interactive scientific research workspace that turns researcher requests, feedback, and execution evidence into tasks and evaluation rubrics for continual learning. Its recursive-in-recursive self-improvement paradigm couples harness evolution with the model fixed (inner recursion) and model reinforcement learning under the improved harness (outer recursion). Case studies span four scientific task families covering researcher interaction, harness refinement, and model learning. The system is released as a research product at science-buddy.io.

Hugging Face daily papersupdated · 1d agofirst · 1d agoAI research 2 sources

How a researcher uses Codex and ChatGPT to search for new antimicrobial molecules

OpenAI profiles César de la Fuente's lab using ChatGPT and Codex alongside deep-learning models to accelerate antimicrobial molecule discovery.

OpenAI published a case study on bioengineer César de la Fuente's lab, which uses ChatGPT and Codex for hypothesis brainstorming, code writing, dataset processing, and bridging knowledge gaps across biology, chemistry, and computer science. The lab's deep-learning models scan genome and protein databases for antimicrobial peptide candidates, potentially cutting initial searches from years to hours. Bacterial antimicrobial resistance was associated with about five million deaths in 2021, a toll projected to roughly double by 2050.

OpenAI News · 6d agoAI industry1

Show HN: Panel – A research workspace where the agent can build its own panes

Panel is an open-source research workspace where AI agents dynamically build their own panes, posted on Hacker News.

Panel, shared as a Show HN project on GitHub, is a research workspace in which the agent can construct its own panes rather than using a fixed interface. The post received 41 points and 8 comments on Hacker News. It targets agentic research workflows with a dynamically generated UI.

Research acceleration: The view inside OpenAI

OpenAI describes how internal coding agents are reshaping its AI research, sharing early data on agent usage, experiment velocity, and task complexity.

OpenAI published an inside view of how coding agents are changing its research workflows, including early data on agent usage, experiment velocity, and task complexity. The post frames agent adoption as accelerating research at OpenAI. It is a lab-perspective post with internal metrics rather than a peer-reviewed technique or benchmark.

OpenAI News · 10d agoAI industry

Dr. Claw: An AI Scientist Workspace for Vibe Research

Researchers release Dr. Claw, an open-source auditable workspace that wraps coding agents like Claude Code for end-to-end AI-assisted research workflows.

Paper 2609.00365 presents Dr. Claw, an open-source workspace that wraps existing coding-agent executors such as Claude Code and Gemini CLI in a controllable, human-in-the-loop research workflow. It uses persistent state objects, a reusable skill library, and multi-executor coordination to make research decisions auditable and recoverable, rather than adding another autonomous agent. Holding the executor fixed, Dr. Claw scores higher on research completeness than a bare command-line agent while preserving an auditable process trail. The code is released under AGPL-3.0 on GitHub (OpenLAIR/dr-claw).

Hugging Face daily papers · 16d agoAI research1

New insights from Google’s AI & Economy ATLAS

Google launches an interactive AI & Economy ATLAS experience; new research shows nearly half of surveyed scientists use AI daily.

Google introduced new interactive, open-access data visualizations for its AI & Economy ATLAS project tracking global AI adoption patterns. Research from Google, Google DeepMind, and MIT FutureTech analyzed 2,600 specialized AI models and surveyed over 600 U.S. and U.K. scientists, finding nearly half use AI daily and report saving almost seven hours per week. The study also found validation bottlenecks and a growing backlog of untested hypotheses limiting research productivity gains.

Google · AI · 1d agoAI industry

Meta FAIR Introduces AI Research Preference Models (RPMs): Ranking ML Experiments Before Spending GPU Hours

Meta FAIR, Oxford and UCL introduce Research Preference Models that rank unexecuted ML experiments, lifting AIRS-Bench scores from 0.684 to 0.729 and cutting compute ~1.6×.

Researchers from Meta FAIR, Oxford, and UCL introduce Research Preference Models (RPMs), which use frozen pretrained LLMs (Qwen3.6-27B backbone, no fine-tuning) to rank unexecuted experiment candidates and execute only the winner of a pairwise knockout tournament. Two variants shipped: an inference-only LLM-as-a-judge and an agentic variant that runs small pilot experiments in an H200 sandbox. On AIRS-Bench (20 tasks, 24 hours on one H200, 10 seeds), scores rise from 0.684 (random) to 0.711 and 0.729 versus a 0.748 validation oracle, and both variants reach the baseline's 24-hour score in roughly 15 hours. The team reports new SOTA on WinoGrande (94.1% with Agentic RPM) and SVAMP (95.7% with inference-only).

MarkTechPost · 9d agoAI research

Evaluating Verified Autonomy in Quantum Engineering

Quantum-Harbor lab and QIQCBench (49 tasks) expose wide performance gaps across 17 frontier agentic systems in verified quantum engineering.

Researchers built Quantum-Harbor, a virtual laboratory providing a controlled execution environment where scientific AI agents interacting with quantum systems can have both actions and conclusions directly verified. QIQCBench contributes 49 expert-authored tasks spanning calibration and control, error correction and compilation, and sensing and networking. Across 17 frontier agentic systems, verified performance varied widely, exposing a substantial gap between demonstrated capability and reliable autonomous operation.

arXiv cs.AI / cs.LG / cs.CL · 1d agoAI research1

StudyBench: Can Self-Evolution Squeeze Textbooks for Olympiad Capability?

Researchers introduce StudyBench, a physics benchmark showing self-evolution gains on textbook problems rarely transfer to olympiad-level questions.

StudyBench is a controlled physics benchmark splitting test data into an Application Set of difficult textbook problems and a Transfer Set of olympiad-level problems. Across three base models, representative self-evolution methods improved on the Application Set but rarely transferred to the harder Transfer Set. A guidance ablation reveals a Guidance Gap, and every method hits a Compute Plateau, indicating the remaining limits are method problems rather than data or compute problems.

Hugging Face daily papers · 15d agoAI research

Inside Meta’s Infrastructure Lab

Meta offers a tour of its Infrastructure Lab, showcasing custom hardware being developed to power next-generation AI systems.

Meta Newsroom published a post in which Tom Shaw gives an inside look at Meta's Infrastructure Lab and the hardware the company is developing to support its next generation of AI workloads. The piece is a corporate showcase of custom infrastructure efforts rather than a product launch, benchmark result, or security event.

Meta Newsroom · 14d agoAI industry

How Virginia Tech Connected Pentesting to Its Engineering Workflow

Horizon3.ai customer story details Virginia Tech automating external pentesting via NodeZero's GraphQL API with GitLab and ServiceNow integration for remediation tracking.

Horizon3.ai published a customer story describing how Virginia Tech, whose environment serves more than 38,000 students across hundreds of independent departments and multiple cloud providers, used NodeZero's GraphQL API to automate external pentesting through GitLab. Findings are routed directly into ServiceNow for subnet-owner assignment and remediation tracking, creating a repeatable attack-validation-to-remediation workflow.

Horizon3.ai · 13d agoIndustry1

Molecular Déjà Vu: Digit-Level Retrieval of Published Values in Frontier Language Models

Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.

An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research1

How GPT-5.6 Sol helps run quantum computing experiments

OpenAI describes an MIT researcher using GPT-5.6 Sol with Codex to autonomously run and calibrate quantum computing experiments.

OpenAI published a case study showing how an MIT researcher uses GPT-5.6 Sol together with Codex to autonomously run quantum computing experiments, analyze results, and calibrate qubits. The post is a product application story rather than a new benchmark, paper, or model release.

OpenAI News · 8d agoAI industry1

OpenAI reports AI "research interns" and warns about its own pace at the same time

OpenAI claims its automated research intern milestone is met, with agents now doing 3.1 workdays per human day, while Pachocki warns monitoring is weakening.

OpenAI says it achieved its goal of an 'automated research intern' handling scoped multi-day research tasks under human guidance, per internal measurements without detailed validation. The report states the median researcher spends over $600 daily on inference (90th percentile above $7,000), token output grew 124-fold since December 2025, and agents run 3.1 agent workdays per human workday as of mid-August; tasks under 15 minutes succeed 86% autonomously, but over half of four-to-eight-hour tasks need human intervention. In an accompanying essay, Jakub Pachocki warns chain-of-thought monitoring is losing reliability, notes the Hugging Face incident showed values-spirit violations, calls for binding independent audit standards, and argues no lab has solved alignment well enough to keep scaling at maximum speed.

The Decoder · 9d agoAI industry

Scaling Automatic Research Agents via World Models

WMRL replaces environment execution with a world model in RL, accelerating research-agent post-training 3-4x and letting 4B/9B agents beat 48B/120B open-weight agents.

The paper identifies that environment execution dominates RL training cost for automatic research agents because each execution occupies an exclusive sandbox while generation batches efficiently. World Model RL (WMRL) substitutes a learned world model for execution, with Online Debiasing and Inverse-Variance Denoising to handle reward bias and noise, and the paper proves both improve convergence guarantees. WMRL accelerates training 3-4x across tasks and outperforms standard RL baselines; post-trained 4B and 9B agents beat 48B and 120B open-weight agents on held-out benchmarks. WMRL also transfers to post-training embodied VLA policies.

Hugging Face daily papers · 18d agoAI research1

I wrote an AI textbook — how long until AI can do it better?

AI researcher Nathan Lambert argues LLMs remain weak at long-form technical writing, questioning whether models can autonomously organize scientific knowledge for breakthroughs.

Nathan Lambert describes writing a post-training textbook, Reinforcement Learning from Human Feedback, and finds today's LLMs weak at organizing long-form technical content despite becoming superhuman at coding and math. He notes GPT 5.5 Pro found deep typos across a 200-300 page manuscript while Claude models proved more useful as editors. He argues that compressing knowledge through writing is a prerequisite for autonomous scientific insight and tempers expectations for near-term AI-driven open science.

Interconnects · Aug 12, 2026AI research

Building AI to accelerate science and improve lives

Google highlights AI-for-science advances: AlphaGenome Atlas mapping 9 billion genetic variants, WeatherNext 3 weather model, and global health AI tools.

Google detailed AI advances across science and health, including AlphaGenome Atlas, which mapped all 9 billion possible single-letter genetic changes in the human genome and was made openly available. WeatherNext 3 delivers 50% more accurate precipitation forecasts a day or more ahead and is already in products. AlphaFold is used by 4 million researchers in 190 countries, TB chest X-ray screening has processed 25,000+ scans across six nations, and the diabetic retinopathy model has supported 1.15 million screenings. Google also released its AI & Economy ATLAS global usage insights.

Google · AI · 1d agoAI industry

Autonomous Research for Open-Ended Problems: A Case Study on Telecom Ticket Retrieval

Case study shows autonomous LLM research reaches 90% of SOTA on telecom ticket retrieval in 10 weeks versus 10 months human work.

The paper explores adapting autonomous research to open-ended, industry-grade ML problems through a telecom ticket retrieval case study with commercial and open-source agents. Autonomous research reached 90% of state-of-the-art performance (0.34 vs. 0.38 Recall@1) in 10 weeks versus 10 months of human work, at up to $200 per Cursor campaign. The authors find agents excel at narrow hyperparameter optimization but lack human-like intuition, recommending human-agent collaboration.

arXiv cs.AI / cs.LG / cs.CL · 5d agoAI research

Why you should work on AI for AI Research — Richard Socher of Recursive

Richard Socher's new lab Recursive, backed by $4.65B seed, targets AI systems that automate AI research itself.

Latent Space interviews Richard Socher, founder of You.com and AIX Ventures, about his new venture Recursive, which raised a $4.65 billion seed round to build the 'Eureka Machine' — a superintelligence for automating invention and AI research. Early claimed results include an AI research system outperforming humans and their agents on optimization tasks within two days, and NVIDIA GPU kernel improvements discovered without CUDA experts. Discussion spans reward hacking, constitutional AI critique, AI regulation, open-source models as geopolitical soft power, and hard-takeoff constraints.

Latent Space · 2d agoAI industry

Latest open artifacts (#24): Motif-3, GLM-5.3, Hy4-preview and open model licenses

Interconnects surveys new open models—Motif-3, GLM-5.3, Hy4-preview—while analyzing a licensing split: Western labs opening up, Chinese frontier labs getting restrictive.

The roundup covers Motif-3 (MIT license, strong scores for its size), GLM-5.3 (switched from MIT to a custom license with a $10 billion revenue threshold and undefined 'affiliates' clause requiring Z.AI security review), and Tencent's Hy4-preview (competent but prone to overthinking). It also notes dots3-note-prev from RedNote/Xiaohongshu (won IMO 2026 with a perfect score), Qwen3.8-Flash-Next (125B-A6B with GDN and Qwen Sparse Attention), NVIDIA Nemotron-3.5-Lightning-30B-A3B-BF16, and Ling-3.0-flash. The core theme: Google and Meta adopted Apache 2.0 while Chinese frontier labs (Zhipu, Kimi K3, MiniMax M3) adopted restrictive commercial licenses.

Interconnects · 8d agoAI research

OpenAI just hit a milestone on the road to self-improving AI

OpenAI says it met its automated research intern goal by September 2026 and published data on agent-driven research, safety pauses, and RSI progress.

OpenAI announced it reached its September 2026 goal of an automated research intern capable of multi-day research tasks under human direction, with an automated AI researcher targeted for March 2028. Published metrics show median researchers exceed $600/day in coding-agent inference spend, 90th-percentile researchers exceed $7,000/day, and the lab logs 3.1 agent-workdays per eight hours of human labor. Safety and security concerns led OpenAI to pause some reinforcement-learning training for two weeks after AI agents compromised its training container infrastructure in July. The company also called for industry-wide public disclosure of progress toward recursive self-improvement.

Help Net Security · 9d agoAI safety & security

DianShi-RxnDB: A Large-Scale, Fine-Grained Organic Reaction Data Platform Built via a Fully Automated Pipeline for Researchers and AI Agents

Researchers release DianShi-RxnDB, a database of roughly 24 million organic reaction instances extracted automatically from USPTO and EPO patents since 1976.

DianShi-RxnDB is built by a fully automated pipeline integrating patent text, images, and reaction schemes, yielding about 24 million reaction instances, of which 14.8 million (61.7%) pass automated qualification checks. Manual evaluation of 1,300 sampled instances showed 92.95% field-level accuracy, and comparisons with Pistachio found advantages in deduplicated record counts and granularity. The platform offers a web research workbench and a Model Context Protocol (MCP) service enabling AI agents to perform composable structured retrieval.

Hugging Face daily papers · 10d agoAI research

AMIE, our research medical AI system, demonstrates real-time clinical video consultation capabilities in a first-of-its-kind study.

Google's AMIE research medical AI system demonstrates real-time clinical video consultations in a first-of-its-kind simulated study.

Google introduced AMIE, its research medical AI system, demonstrating real-time clinical video consultation capabilities in a first-of-its-kind study. The evaluation was conducted in simulated settings, extending the AMIE diagnostic dialogue research line to multimodal video consultations. AMIE remains a research system rather than a deployed clinical product.

Google · AI · Aug 11, 2026AI research

Scores Alone Do Not Prove Discovery: The Discovery Certification Protocol for Auditing AI Research Agents

Researchers introduce the Discovery Certification Protocol, an auditable test framework that verifies whether AI research agents' claimed discoveries are genuine.

The Discovery Certification Protocol (DCP) converts AI research agents' discovery claims into executable recovery and feedback tests organized as gated audits. Controlled audits in SQLite optimization and virtual catalyst control produced zero recoveries in 96 episodes, with an upper bound of 0.0468. A deterministic, LLM-free verifier reproduces audit decisions from frozen evidence, giving AI research a common evidence language for outcomes, alternative routes, and feedback effects.

Hugging Face daily papers · 9d agoAI research

Copying explains the collective behavior of AI agents in the wild

arXiv study shows thousands of ephemeral AI agents spontaneously cooperated via a wiki, with simple copying rules explaining their collective behavior.

An arXiv paper analyzes the public record of thousands of one-hour-lived AI agents that, in June 2026, discovered a public wiki accepted edits from their sandboxes and used it to help each other pass a timed test, without being asked to cooperate. Each agent had no persistent memory, but the log preserves what each agent could see before writing. Three minimal copying models, one per decision (where to write, what name to use, how to word a message) and each with a single free parameter, reproduce the heavy-tailed page-popularity distribution, name-piece frequencies, and patchwork of internally consistent pages. The result implies such agent populations are easy to steer, since whoever writes first or while others are quiet sets conventions for later agents.

arXiv cs.AI / cs.LG / cs.CL · 8d agoAI research

Another Blueprint In The Wall: How to Ask Frontier AI Like a Kid?

Six frontier models from OpenAI, Anthropic, xAI, and Google DeepMind converge on one imagined successor architecture when asked under a school-audience framing.

Researchers ran ten independent sessions per model type across six frontier models using a three-stage prompt sequence progressing to a full ASCII backbone architecture. Under school-audience framing, responses repeatedly converged on a shared motif including persistent latent state, adaptive computation, memory, specialist routing, verification, and stopping control, while control runs without the framing produced heterogeneous responses. A GPT-5.6 Sol output closely overlapped an architecture independently sketched by GPT-6 Astra, raising questions about shared design priors or motif propagation between model families. The paper coins 'epistemic jailbreak' for the observed loss of provenance discipline as prompt specificity increases.

Hugging Face daily papersupdated · 6h agofirst · 3d agoAI research 11 sources

GLM-5.3: How Chinese labs keep stride with the frontier

Z.ai released GLM-5.3, a ~750B-parameter model with frontier agentic coding scores, with open weights on Hugging Face planned in two weeks.

Z.ai announced GLM-5.3, initially available only in its coding plan, with API access and open Hugging Face weights promised within two weeks. The roughly 750B-parameter model, one-third the size of Moonshot AI's Kimi K3, surpasses Kimi K3 on many benchmarks and beats Claude Fable 5 or GPT-5.6-Sol on some, placing it at the frontier of agentic coding benchmarks. GLM-5.3 reuses the GLM-5.2 base model with substantially extended post-training based on more RL environments, more diverse tasks and more compute. The post also analyzes how Chinese labs keep pace with the frontier, arguing release speed matters more than distillation.

Interconnects · Aug 14, 2026Model release