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Stanford Researchers Release Paper2Agent: Turning Research Papers Into AI Agents That Reproduce Results and Run on New Data

Stanford researchers released Paper2Agent, a Nature-published pipeline that turns research papers into MCP servers agents can execute.

A Stanford team led by Jiacheng Miao and James Zou published Paper2Agent in Nature on 16 September 2026. Built on Claude Code's agent SDK, it converts a paper and its codebase into a Model Context Protocol server with validated tools, resources, and prompts. In benchmarks, the AlphaGenome agent built 22 tools in about 45 minutes for US$14, scored 100% on 15 novel queries versus 78.7% for Claude Code with repository access, and cut median runtime 1.9x. In scale tests, 74 of 100 bioRxiv papers were converted and 593 of 599 proposed tools passed validation.

MarkTechPost · 10h agoAI research1

Sakana AI Researchers Introduce PC-ALM, a Layer-Local Alternative to Backpropagation That Trains 1000-Layer Networks

Sakana AI's PC-ALM adds per-layer Lagrange multipliers to predictive coding, matching backprop on networks up to 1000 layers with layer-local updates.

Sakana AI researchers propose Augmented Lagrangian Predictive Coding (PC-ALM), a training method that keeps every update layer-local while recovering backprop-aligned credit signals. The team proves multipliers converge to exact backprop adjoints in linear networks and trains 1000-layer residual MLPs on MNIST within about 2 points of backprop accuracy. PC-ALM matched backprop across a width/depth grid from 8 to 128 on MNIST and Fashion-MNIST where standard predictive coding failed in deep, narrow networks, and improved over PC on ResNet-18 with CIFAR-10 and Tiny ImageNet. An MIT-licensed JAX reference implementation reproduces the results on CPU.

MarkTechPost · 2d agoAI research2

[AINews] Reality Checks on AI News (Yegge shuts down Gas Town, Databricks’ +60% Astra cost)

Latent Space AI news roundup: Steve Yegge shuts down Gas Town, Databricks reports 60% higher coding spend on GPT-6 Astra, OpenAI launches misalignment disclosure framework.

Latent Space's AI News digest for September 15-16, 2026 leads with Steve Yegge shutting down his Gas Town orchestrator despite spending thousands monthly on coding-agent subscriptions. Databricks rolled out GPT-6 Astra to roughly 3,500 engineers, reporting superior long-horizon performance over Opus 5 and Sol 5.6 but a ~60% increase in coding spend. OpenAI published a formal framework for disclosing model misalignment incidents with six case reports, while Microsoft and Google Research released safety papers on 'capability laundering' and the Fuse motive-inference benchmark. Xiaomi shared live RL training telemetry for MiMo-V2.6, estimated at $493k/day for the 1T-class Pro run.

Latent Space · 1h agoAI industry 12 sources

Fly Language Model (FLM) Wires the Full Fruit Fly Connectome Into a Frozen 1.2B LLM, and Its Own Controls Show the Wiring Does Not Help

Researchers wire the full fruit fly connectome (166,700 nodes) into a frozen LiquidAI LFM2.5-1.2B LLM, but controls show no fly-specific benefit.

The Fly Language Model (FLM) couples the complete MaleCNS v1.0 fruit fly connectome (166,700 nodes, 25,582,938 edges) to a frozen LiquidAI LFM2.5-1.2B-Instruct backbone, training only a 278,528-parameter readout (~0.0238% of backbone parameters). The fly readout improved NLL by 0.0222 nats/token (perplexity 3.98 to 3.90) on 32 SmolTalk dialogues, but a direct-input control without the graph beat it in all three seeds. Relabeling node identities removes the gain and the recurrence contracts state differences by 0.6 per token, so the connectome adds no long-range memory. The MIT-licensed code runs locally on Python 3.12, but study artifacts remain private, limiting independent reproducibility.

MarkTechPost · 4d agoAI research1

[AINews] DeepSeek v4.1-Flash: 763B-P8B-D16B novel causal Encoder–Decoder architecture with vision marks the Return of the Whale

DeepSeek released V4.1-Flash, an open-weight 763B-parameter model with a novel causal encoder-decoder architecture, 1M context, vision input, and MIT license.

DeepSeek launched V4.1-Flash, an open-weight MIT-licensed model using a novel causal encoder-decoder architecture with 763B total parameters and asymmetric active parameters: 8B for prefill and 16B for decode. It supports 1M-token context and text+image input, priced at $0.30 per 1M input and $1.20 per 1M output tokens with a 50% off-peak discount. Artificial Analysis scored it 40 on its Intelligence Index, above DeepSeek V4 Pro 0813, and Vals ranked it the #1 open-weight model ahead of Kimi K3. Baseten shipped day-0 support and Ollama began rolling it out to paid subscribers.

Latent Space · 5d agoModel release 2 sources1

Nous Research Adds One-Click Local Model Setup to Hermes Desktop

Nous Research's Hermes Desktop now offers one-click local model setup that reads hardware, picks a fitting quantization, downloads weights, and configures llama.cpp automatically.

Hermes Desktop, the MIT-licensed build of the open-source Hermes Agent, now sets up local models in one click: it reads the machine's hardware, selects a model that fits, downloads weights, and configures the inference runtime. It manages a pinned llama.cpp build with CUDA, Metal, Vulkan, HIP, and CPU backends, and shows green/amber/red memory-fit verdicts per catalog model before download. Quantization floors at 4-bit, and recommended models guarantee at least a 64K context window protected by ordered RAM offload (expert weights first, never the attention cache). It runs on macOS 12+, Windows 10/11, and Linux with no account required for local models.

MarkTechPost · 11d agoAI tools & infra1

[AINews] NVIDIA buys HuggingFace for $13B, as OpenAI publishes their HF incident retro

Z.ai released open-weight GLM-5.3-Flash (320B/18B active, 1M context, MIT) while Nvidia confirmed buying Hugging Face for $13B.

Z.ai formally launched GLM-5.3-Flash, the model previously previewed as Ox Alpha: 320B total parameters with 18B active, a 1M-token context window, natively multimodal, MIT-licensed, and claimed on par with Claude Opus 4.8 on coding. Artificial Analysis scored it 57 on its Intelligence Index at $0.09 per task, roughly 7.5x cheaper than GLM-5.3, and it scored 84.3% on Terminal-Bench 2.1. Nvidia's $13B acquisition of Hugging Face (~80x its $150M ARR) was confirmed, nearly double its initial $7B January offer. The roundup also notes Qwen shipping an impressive Flash model on Chinese chips as part of a broader open-model narrative.

Latent Space · 21d agoModel release1