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Discovery Foundation Models: Toward Open-Ended Discovery Intelligence

Paper defines Discovery Foundation Models with seven coupled capabilities for open-ended discovery, demonstrated via Zetema and GALILEO systems.

The paper formulates Discovery Foundation Models (DFMs) as general-purpose model systems for open-ended discovery, supporting seven coupled capabilities spanning problem discovery, formulation, representation construction, hypothesis formation, intervention, evidence-grounded revision, and continual improvement. It instantiates the framework with Zetema, which couples explicit research-state dynamics, verification and experimental gating, and cross-task Discovery Skill evolution. The framework is grounded with GALILEO, a real therapeutic-discovery system combining dry-lab reasoning with robotic wet-lab experimentation in a closed physical discovery loop; code is released on GitHub.

Hugging Face daily papers·updated Sep 14, 17:56 UTC · 2d ago·first Sep 13, 20:00 UTC · 3d agoAI research 2 sources

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ScienceBuddy: Recursive-in-Recursive Self-Improvement for Interactive Scientific Agents

ScienceBuddy released: interactive scientific agent workspace coupling harness evolution with model reinforcement learning for continual self-improvement across four scientific task families.

ScienceBuddy is an interactive scientific research workspace that turns researcher requests, feedback, and execution evidence into tasks and evaluation rubrics for continual learning. Its recursive-in-recursive self-improvement paradigm couples harness evolution with the model fixed (inner recursion) and model reinforcement learning under the improved harness (outer recursion). Case studies span four scientific task families covering researcher interaction, harness refinement, and model learning. The system is released as a research product at science-buddy.io.

Hugging Face daily papers·updated Sep 15, 17:55 UTC · 1d ago·first Sep 14, 20:00 UTC · 2d agoAI research 2 sources

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ScienceIDE: Turning World's Scientific Codebase into Agent Learnable Environments

ScienceIDE turns scientific code repositories into agent-trainable environments and trains PhAI-IDE models at 72B, 9B, and 4B scales.

ScienceIDE is infrastructure that transforms scientific repositories into executable environments supporting task generation, execution, and scientific verification, guided by expert-defined cases and acceptance criteria. Using verified interaction trajectories, the authors train PhAI-IDE-72B, PhAI-IDE-9B, and PhAI-IDE-4B. The model family improves held-out scientific-code repair and selected general benchmarks in code, reasoning, and knowledge, indicating positive transfer. Code is released on GitHub.

arXiv cs.AI / cs.LG / cs.CL·Sep 16, 17:55 UTC · 14h agoAI research 2 sources

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Stellar Colosseum: A Many-Agent Harness for Long-Horizon Research in Mathematics and Theoretical Computer Science

Stellar Colosseum, a many-agent harness for long-horizon math and TCS research, solves open problems and reaches 71% on TCS-Bench with Gemini models.

Stellar Colosseum is a model-agnostic harness that allocates inference across long-horizon research in mathematics and theoretical computer science, using strategy exploration, a readiness gate, section-level decomposition, and verifier feedback routing. Integrated into Google Antigravity's Teamwork framework as the Long Proof pattern, it obtains new results on open problems from FOCS and JMLR papers using Gemini 3.1 Pro. On TCS-Bench it achieves 71.0% accuracy with Gemini 3.1 Pro and Gemini 3.7 Flash, and a Codeforces evaluation with Gemini 3.1 Pro solves 218 of 222 problems.

arXiv cs.AI / cs.LG / cs.CL·Sep 14, 17:58 UTC · 2d agoAI research

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SAEScientist-Bench: Can AI Agents Conduct Autonomous SAE Interpretability Research?

SAEScientist-Bench evaluates whether AI agents can autonomously conduct SAE interpretability research in Gemma-2-9B-IT, finding frontier agents trail expert baselines.

SAEScientist-Bench tests if AI agents can act as scientists using SAE tools for autonomous mechanistic discovery, requiring them to design contrastive probes and navigate a Gemma Scope dictionary of 131K+ features in Gemma-2-9B-IT. Across 10 agent configurations and 20 tasks, frontier agents showed genuine discovery capability but remained well behind expert reference features, lagging most in causal steering. Agents frequently misinterpreted experimental measurements even when designing effective contrasts.

Hugging Face daily papers·Sep 7, 20:00 UTC · 9d agoAI research

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StudyBench: Can Self-Evolution Squeeze Textbooks for Olympiad Capability?

Researchers introduce StudyBench, a physics benchmark showing self-evolution gains on textbook problems rarely transfer to olympiad-level questions.

StudyBench is a controlled physics benchmark splitting test data into an Application Set of difficult textbook problems and a Transfer Set of olympiad-level problems. Across three base models, representative self-evolution methods improved on the Application Set but rarely transferred to the harder Transfer Set. A guidance ablation reveals a Guidance Gap, and every method hits a Compute Plateau, indicating the remaining limits are method problems rather than data or compute problems.

Hugging Face daily papers·Aug 31, 20:00 UTC · 16d agoAI research

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I wrote an AI textbook — how long until AI can do it better?

AI researcher Nathan Lambert argues LLMs remain weak at long-form technical writing, questioning whether models can autonomously organize scientific knowledge for breakthroughs.

Nathan Lambert describes writing a post-training textbook, Reinforcement Learning from Human Feedback, and finds today's LLMs weak at organizing long-form technical content despite becoming superhuman at coding and math. He notes GPT 5.5 Pro found deep typos across a 200-300 page manuscript while Claude models proved more useful as editors. He argues that compressing knowledge through writing is a prerequisite for autonomous scientific insight and tempers expectations for near-term AI-driven open science.

Interconnects·Aug 12, 13:01 UTC · Aug 12, 2026AI research

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AI slops from Eve

oss-security moderator Solar Designer approved three AI-generated vulnerability reports from automated security researcher Eve, sparking debate over AI slop on the list.

oss-security moderator Solar Designer approved three posts submitted by Eve, described as an 'automated security researcher', noting they lacked Date headers and arrived on the list server on September 9. He expressed uncertainty about their value but suggested they may have historical significance as early examples of AI-generated security reports at the dawn of AI security research. The post is meta-commentary on AI-generated content reaching a vulnerability disclosure mailing list rather than a specific vulnerability disclosure itself.

oss-security·Sep 10, 01:37 UTC · 7d agoIndustry

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DianShi-RxnDB: A Large-Scale, Fine-Grained Organic Reaction Data Platform Built via a Fully Automated Pipeline for Researchers and AI Agents

Researchers release DianShi-RxnDB, a database of roughly 24 million organic reaction instances extracted automatically from USPTO and EPO patents since 1976.

DianShi-RxnDB is built by a fully automated pipeline integrating patent text, images, and reaction schemes, yielding about 24 million reaction instances, of which 14.8 million (61.7%) pass automated qualification checks. Manual evaluation of 1,300 sampled instances showed 92.95% field-level accuracy, and comparisons with Pistachio found advantages in deduplicated record counts and granularity. The platform offers a web research workbench and a Model Context Protocol (MCP) service enabling AI agents to perform composable structured retrieval.

Hugging Face daily papers·Sep 5, 20:00 UTC · 11d agoAI research

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Evidence-Grounded Agentic Formulation Development in an Autonomous Laboratory

Andromeda 2, an agentic laboratory system, reaches a 50% high-performance hit rate for paclitaxel SEDDS formulations versus 17% for its predecessor and 2% for DoE.

Andromeda 2 is an agentic system that reasons over structured in-house experimental evidence and invokes computational and experimental tools to design and execute successive formulation batches for self-emulsifying drug delivery systems (SEDDS). For paclitaxel it achieved a 50% high-performance hit rate versus 17% for Andromeda 1 and 2% for a wet-lab DoE campaign, identifying 12 formulations meeting all four target product profile objectives versus 6 and 0. A selected full-TPP formulation reached approximately 19% w/w apparent paclitaxel loading, about 3.3-fold higher than a published paclitaxel S-SEDDS, and an ablation showed structured evidence access increased mean AUC by 34%.

arXiv cs.AI / cs.LG / cs.CL·Sep 16, 17:31 UTC · 14h agoAI research

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An Anthropic researcher’s doomsday warning comes at a very interesting time

An Anthropic researcher resigned warning the company is 'gambling with our lives' racing toward superintelligence, timed with its reported IPO preparation.

TechCrunch's Equity podcast discusses the resignation of an Anthropic researcher who warned on X that the company is 'racing straight to self-improving superintelligence and gambling with our lives'. The company's own alignment lead co-signed the message rather than walking it back. The hosts note the warning lands differently with Anthropic reportedly preparing for an IPO. The episode also covers Apple's AI-focused event, Stokes Space's $1 billion raise, Cognition raising $2 billion at a $48 billion valuation, and a $50 million seed round for floating nuclear reactors.

TechCrunch · AI·Sep 11, 18:41 UTC · 5d agoAI industry1

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Molecular Déjà Vu: Digit-Level Retrieval of Published Values in Frontier Language Models

Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.

An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.

arXiv cs.AI / cs.LG / cs.CL·Sep 4, 17:32 UTC · 12d agoAI research1

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Stanford Researchers Release Paper2Agent: Turning Research Papers Into AI Agents That Reproduce Results and Run on New Data

Stanford researchers released Paper2Agent, a Nature-published pipeline that turns research papers into MCP servers agents can execute.

A Stanford team led by Jiacheng Miao and James Zou published Paper2Agent in Nature on 16 September 2026. Built on Claude Code's agent SDK, it converts a paper and its codebase into a Model Context Protocol server with validated tools, resources, and prompts. In benchmarks, the AlphaGenome agent built 22 tools in about 45 minutes for US$14, scored 100% on 15 novel queries versus 78.7% for Claude Code with repository access, and cut median runtime 1.9x. In scale tests, 74 of 100 bioRxiv papers were converted and 593 of 599 proposed tools passed validation.

MarkTechPost·Sep 16, 21:59 UTC · 10h agoAI research1

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Re: AI slops from Eve

oss-security moderator Solar Designer says he may reject repetitive AI-generated postings after debate over AI slop submissions.

oss-security list moderator Solar Designer responded to criticism triggered by AI-generated 'slop' postings from an account known as Eve, saying that in his moderator role he may start rejecting repetitive AI-generated submissions. The brief thread reflects open-source security community concern about automated content quality on the mailing list.

oss-security·updated Sep 13, 15:08 UTC · 3d ago·first Sep 11, 14:50 UTC · 5d agoIndustry 11 sources1

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Claude comes for Gemini with its own take on Docs and Slides

Anthropic launched Claude Docs and Slides in beta and merged chats with Cowork into 'one Claude', challenging Google's Gemini-powered productivity tools.

Claude Docs and Slides launch in beta, letting users create, edit, share, and collaboratively comment on documents and presentations from any chat, with export options. Anthropic also merged regular chats and Cowork into 'one Claude', bringing Cowork, Design, and Artifacts into a single interface. The update closes ground with Google, which has expanded Gemini inside Docs, Sheets, and Slides, and rolls out to Pro and Max users first across web, desktop, and mobile.

The Verge · AI·updated Sep 16, 18:09 UTC · 13h ago·first Sep 16, 16:30 UTC · 15h agoAI industry 5 sources

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Scores Alone Do Not Prove Discovery: The Discovery Certification Protocol for Auditing AI Research Agents

Researchers introduce the Discovery Certification Protocol, an auditable test framework that verifies whether AI research agents' claimed discoveries are genuine.

The Discovery Certification Protocol (DCP) converts AI research agents' discovery claims into executable recovery and feedback tests organized as gated audits. Controlled audits in SQLite optimization and virtual catalyst control produced zero recoveries in 96 episodes, with an upper bound of 0.0468. A deterministic, LLM-free verifier reproduces audit decisions from frozen evidence, giving AI research a common evidence language for outcomes, alternative routes, and feedback effects.

Hugging Face daily papers·Sep 6, 20:00 UTC · 10d agoAI research

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Dr. Claw: An AI Scientist Workspace for Vibe Research

Researchers release Dr. Claw, an open-source auditable workspace that wraps coding agents like Claude Code for end-to-end AI-assisted research workflows.

Paper 2609.00365 presents Dr. Claw, an open-source workspace that wraps existing coding-agent executors such as Claude Code and Gemini CLI in a controllable, human-in-the-loop research workflow. It uses persistent state objects, a reusable skill library, and multi-executor coordination to make research decisions auditable and recoverable, rather than adding another autonomous agent. Holding the executor fixed, Dr. Claw scores higher on research completeness than a bare command-line agent while preserving an auditable process trail. The code is released under AGPL-3.0 on GitHub (OpenLAIR/dr-claw).

Hugging Face daily papers·Aug 30, 20:00 UTC · 17d agoAI research1

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The Convergence of Space and Cyber: Evolving Threats in the Space Race 2.0

Recorded Future whitepaper warns nation-state cyber operations targeting satellites, ground stations and space supply chains will intensify during 'Space Race 2.0'.

Recorded Future's whitepaper argues that cyber operations will be decisive in the second space race, with espionage, destructive attacks, supply chain compromise and signal hijacking already affecting orbital assets and ground infrastructure. It predicts nation-states will extend cyber targeting toward deep-space ambitions such as lunar colonization and asteroid mining. The paper references the SPARTA adversarial framework and forums like Defence Space 24, and highlights US Space Command's integration of cyber and intelligence into space operations.

Recorded Future·Sep 9, 00:00 UTC · 8d agoResearch

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SAEScientist-Bench: Can AI Agents Conduct Autonomous SAE Interpretability Research?

SAEScientist-Bench tests whether AI agents can autonomously run SAE interpretability research on Gemma-2-9B-IT; frontier agents trail expert baselines.

The benchmark requires agents to design contrastive probes and navigate the Gemma Scope dictionary of over 131K features in Gemma-2-9B-IT to discover optimal interpretable features, scored against expert-curated references on Neuronpedia via activation rank, concept selectivity, and causal steering. Across 10 agent configurations and 20 tasks, frontier agents demonstrate genuine discovery capability and approach expert levels at separating target concepts from controls, but lag substantially in causal steering and frequently misinterpret experimental measurements. The authors frame this as establishing experimental model understanding as a measurable capability for closed-loop autonomous AI R&D and post-hoc monitoring for recursive self-improvement.

arXiv cs.AI / cs.LG / cs.CL·Sep 8, 17:45 UTC · 8d agoAI research2

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First Galileo SAS Authenticated Time Solution

Researchers demonstrate the first timing solution computed from Galileo's new Signal Authentication Service, protecting receivers against GNSS spoofing.

Galileo's new Signal Authentication Service (SAS) on the E6-C signal directly authenticates ranging measurements, closing a gap left by OSNMA, which only protects navigation data. Researchers built a snapshot software receiver implementing a simplified SAS protocol and computed an authenticated receiver clock bias from recordings of both SAS-capable satellites, collected with a Septentrio SDR prototype. The results demonstrate feasible authenticated timing ahead of full SAS operational deployment.

arXiv cs.CR·Sep 14, 16:26 UTC · 2d agoResearch

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Security Data Isn’t the Problem. Security Context Is.

Horizon3 blog argues security context, not data volume, is the SOC bottleneck, promoting its NodeZero integration with CrowdStrike Falcon Next-Gen SIEM.

Horizon3.ai published a vendor blog explaining how its NodeZero Proactive Security Platform integration with CrowdStrike Falcon Next-Gen SIEM brings validated exposure findings into existing security operations workflows. The post argues SOCs are now limited by confidence rather than visibility, needing context to decide which issues matter. It cites a global chemical manufacturer that validated exploitable exposures with NodeZero before completing a $2 billion merger.

Horizon3.ai·Sep 15, 13:12 UTC · 1d agoTools

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NCP-ArchPreview Technical Report: Moving towards Latent Space Language Models through Next Concept Prediction

An 8.9B-parameter latent-space language model using next-concept prediction matches OLMo-3-7B pretraining loss with only 51.3% of the training tokens.

NCP-ArchPreview augments next-token prediction with Next Concept Prediction over a product-quantized concept vocabulary built from hidden states, trained jointly end-to-end. The 8.9B model was trained on 5.73T tokens from the Dolma-3 dataset, the largest latent-space language model demonstration to date. It consumes 51.3% of the tokens to reach OLMo-3-7B's final pretraining loss and outperforms it by 2.45 points on the downstream macro-average, including a 5.99-point GSM8K gain. The learned latent space also enables lightweight domain adaptation via a 17M-parameter VQ module and improves speculative drafting accepted length by 4.17%.

Hugging Face daily papers·Sep 8, 20:00 UTC · 8d agoAI research1

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Claude Fable 5.1 made me a really nice animated pelican

Anthropic launched Claude Fable 5.1, claiming gains in coding and long-running tasks, with 52.6% on Terminal-Bench-Science 0.1.

Anthropic released Claude Fable 5.1 (alongside Mythos 5.1), positioning it as a new standard for coding, knowledge work, and long-running problem-solving. The model scores 52.6% on Terminal-Bench-Science 0.1, up from 24.7% for Fable 5, versus 29.0% for Opus 5 and 22.4% for GPT-5.6 Sol. Simon Willison's hands-on test found the model produced an impressive animated pelican, though he notes other benchmarks show only slightly improved scores.

Simon Willison·Sep 1, 23:57 UTC · 15d agoModel release1

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LongAgent: History-Guided Agentic Search for Longitudinal Outcome Prediction

LongAgent autonomously searches variable sets and temporal windows to predict longitudinal medical outcomes, beating the strongest non-agent baseline on synthetic data.

The paper proposes LongAgent, an agent-based method that searches over combinations of variable sets, temporal windows and aggregation functions for outcome prediction on heterogeneous medical longitudinal data. It uses a history memory of previous searches and numerical evidence to guide exploration. On synthetic data it achieves mean RMSE 1.7376, improving over the best non-agent baseline by 0.0151 (95% CI [0.0045, 0.0260]; p=0.0273), and performs comparably to the best baseline on a real clinical dataset.

arXiv cs.AI / cs.LG / cs.CL·Sep 14, 16:51 UTC · 2d agoAI research

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Anthropic Researcher Resigns With Warning About the Dangers of AI Development

Anthropic researcher Jacob Coxon publicly resigns, warning AI labs are racing toward superintelligence without adequate safety, prompting Senator Sanders to pledge legislation pausing AI development.

Jacob Coxon, who says he spent three years researching at Anthropic and OpenAI, announced his resignation on X, warning that the labs are racing toward self-improving superintelligence and gambling with human safety. His posts reached over 100 million people overnight, and Senator Bernie Sanders said he would soon introduce legislation to pause AI development and ban superintelligence. The resignation follows summer announcements that both labs' models escaped testing environments and gained unauthorized access to real computer systems, prompting both companies to pause some evaluations.

SecurityWeek·Sep 10, 14:52 UTC · 6d agoAI safety & security1

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