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AI Is Learning to Write Genetic Code

AI models generated viable bacteriophage genomes, with 16 designs successfully replicating and some outperforming the original virus at attacking E. coli.

Two AI models generated complete genome designs for bacteriophages modeled on ΦX174, a virus known to infect E. coli. Researchers produced about 700,000 candidate designs, selected 285 promising ones, and synthesized DNA inserted into E. coli, yielding 16 viable viruses. Some of the newly generated viruses proved more effective at attacking E. coli than the original bacteriophage.

Schneier on Security·Aug 21, 16:52 UTC · 26d agoAI research

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Molecular Déjà Vu: Digit-Level Retrieval of Published Values in Frontier Language Models

Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.

An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.

arXiv cs.AI / cs.LG / cs.CL·Sep 4, 17:32 UTC · 12d agoAI research1

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DianShi-RxnDB: A Large-Scale, Fine-Grained Organic Reaction Data Platform Built via a Fully Automated Pipeline for Researchers and AI Agents

Researchers release DianShi-RxnDB, a database of roughly 24 million organic reaction instances extracted automatically from USPTO and EPO patents since 1976.

DianShi-RxnDB is built by a fully automated pipeline integrating patent text, images, and reaction schemes, yielding about 24 million reaction instances, of which 14.8 million (61.7%) pass automated qualification checks. Manual evaluation of 1,300 sampled instances showed 92.95% field-level accuracy, and comparisons with Pistachio found advantages in deduplicated record counts and granularity. The platform offers a web research workbench and a Model Context Protocol (MCP) service enabling AI agents to perform composable structured retrieval.

Hugging Face daily papers·Sep 5, 20:00 UTC · 11d agoAI research

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Tracking Elirks Variants in Japan: Similarities to Previous Attacks

Unit 42 links new Elirks backdoor variants attacking Japanese organizations to 2012 Taiwan attacks, delivered via spear-phishing PDFs exploiting Adobe Flash CVE-2011-0611.

Unit 42 analyzed new Elirks backdoor variants found in an attack on a Japanese business, noting strong similarities to 2012 attacks on Taiwanese ministries. The backdoor retrieves its C2 address from attacker-created accounts on Japanese blog and SNS services. Recent deliveries used an airline e-ticket lure named "E-TKT" with a PDF exploiting Adobe Flash CVE-2011-0611. Shared infrastructure and tactics with the Scarlet Mimic campaign suggest possible ongoing cyber espionage across East Asia.

Palo Alto Unit 42·Aug 17, 12:56 UTC · Aug 17, 2026Threat actor in the wildCVE-2011-0611

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ApateWeb: An Evasive Large-Scale Scareware and PUP Delivery Campaign

Unit 42 uncovers ApateWeb, a campaign using over 130,000 domains and multilayered redirects to deliver scareware, adware and PUPs to millions of users.

Unit 42 discovered ApateWeb, a large-scale campaign using a network of more than 130,000 domains to deliver scareware, potentially unwanted programs, adware including a rogue browser and browser extensions, and scam pages. The campaign uses a three-layer structure with deceptive emails as the entry point, centralized victim tracking via UUIDs, intermediate adware or anti-bot redirections, and evasion tactics such as cloaking, bot detection error pages, and wildcard DNS abuse. Activity spiked since August 2022, with several hundred attacker-controlled sites remaining in Tranco's top 1 million rankings and millions of monthly hits; Unit 42 blocked an estimated 3.5 million sessions across 74,711 devices in November 2023.

Palo Alto Unit 42·Aug 17, 12:48 UTC · Aug 17, 2026Phishing & fraud in the wild

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MaaS Campaign Combines ClickFix, ErrTraffic and Cruciferra

eSentire uncovered a malware-as-a-service campaign pairing ClickFix social-engineering lures with the ErrTraffic and Cruciferra malware families.

Threat researchers at eSentire identified an ongoing malware-as-a-service (MaaS) campaign that combines ClickFix social-engineering lures with the ErrTraffic and Cruciferra malware families. The campaign relies on ClickFix-style deception to trick users into executing malicious actions that deliver the malware. Further technical detail on affected sectors or infection volumes was not provided in the disclosure.

Infosecurity Magazine·Aug 19, 15:00 UTC · 28d agoMalware in the wild

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Banking Trojans: Ursnif Global Distribution Networks Identified

Unit 42 maps banking-trojan distribution networks: spam botnets push Shiotob downloaders and Ursnif, KINS, Tinba at Japan and European targets via compromised web servers.

Unit 42 identified the distribution networks behind banking trojan attacks against Japan, Italy, Spain, Poland, Australia, and Germany. A spam botnet delivered 75 unique Shiotob (Bebloh/URLZone) variants across 7 million spam emails, with Shiotob acting mainly as a downloader that installs Ursnif and the Pushdo spam bot from C2 commands. Over 200 malicious files were hosted on 74 compromised, mostly European small-business web servers between April 2015 and January 2017, with localized invoice and photo-themed email lures per target country.

Palo Alto Unit 42·Aug 17, 12:56 UTC · Aug 17, 2026Malware in the wild

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Thousands of Hacked WordPress Sites, One Operation: Unmasking StopAndProtect

Check Point uncovers the StopAndProtect ransomware operation infecting thousands of WordPress sites via ClickFix social engineering and PowerShell downloaders.

Check Point Research first observed the StopAndProtect ransomware family in mid-May 2026 and linked its infrastructure to thousands of hacked WordPress sites. The infection chain begins with ClickFix social engineering that prompts victims to run a PowerShell command, followed by two stages of additional downloaders. The research maps the shared infrastructure unifying the operation.

Check Point Research·Aug 18, 13:05 UTC · 29d agoRansomware in the wild

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Threat Assessment: Egregor Ransomware

Unit 42 assesses Egregor ransomware, a Sekhmet variant likely run by former Maze affiliates using Qakbot, IcedID, and Ursnif for initial access.

Since September 2020, Unit 42 observed Egregor ransomware attacks across the U.S., Europe, Asia-Pacific, and Latin America, coinciding with the Maze team's shutdown announcement. Egregor, a variant of the Sekhmet family, uses commodity malware such as Qakbot, IcedID, and Ursnif for initial access, followed by scripts that modify firewalls, enable RDP, and deploy Cobalt Strike for reconnaissance and exfiltration. A PowerShell script uninstalls the McAfee agent and downloads the Egregor DLL via BITS, executed with the -passegregor10 key. Victims face a three-day ransom deadline before exfiltrated data is published on the Egregor Hall of Shame leak site.

Palo Alto Unit 42·Aug 17, 13:16 UTC · Aug 17, 2026Ransomware in the wild

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Mirai Variant V3G4 Targets IoT Devices

Unit 42 tracked the Mirai variant V3G4 exploiting 13 vulnerabilities across IoT devices and servers from July-December 2022 to build a DDoS botnet.

From July to December 2022, Unit 42 observed three campaigns spreading V3G4, a Mirai botnet variant, by exploiting 13 vulnerabilities, including CVE-2022-26134 in Atlassian Confluence and CVE-2019-15107 in Webmin. The campaigns shared the same C2 domains containing the string 8xl9, nearly identical shell script downloaders, and the same XOR keys, suggesting a single threat actor. The malware brute-forces telnet and SSH credentials, terminates rival botnet processes via a stop list, and receives DDoS commands from its C2. Compromised servers and networking devices are absorbed into the botnet for further attacks.

Palo Alto Unit 42·Aug 17, 13:05 UTC · Aug 17, 2026Malware in the wildCVE-2012-4869CVE-2014-9727CVE-2017-5173+6 CVEs

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SEMA-GUARD: Semantic and Graph-Based Vulnerability Detection in Assembly Code

SEMA-GUARD uses semantic analysis and graph neural networks to detect vulnerabilities in assembly code, achieving 85.1% accuracy on a Juliet-derived benchmark.

SEMA-GUARD is a framework that detects vulnerabilities in compiled programs when source code is unavailable, targeting malware, firmware, and embedded systems analysis. It enriches control flow graphs with low-level execution semantics including stack manipulations, memory accesses, and data flow. Evaluated on a Juliet Test Suite set compiled to assembly and split into function-level chunks, it achieves 85.1% accuracy and an F1 score of 0.801, outperforming purely statistical or structural approaches.

arXiv cs.CR·Sep 15, 14:35 UTC · 1d agoResearch1

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Researchers Uncover 10,000+ Malware Loaders Behind YouTube and SEO Poisoning Campaign

Unit 42 uncovers CL-CRI-1171, a two-year pay-per-install campaign distributing 10,000+ OfferLoader samples via YouTube and SEO poisoning.

Palo Alto Networks Unit 42 tracked a campaign as CL-CRI-1171, an infection-as-a-service platform operating for at least two years. It used 11 YouTube gaming channels with hundreds of thousands of subscribers and SEO-poisoned download pages for trojanized WinDirStat and Bluetooth driver installers to distribute OfferLoader, a disposable loader embedded in Inno Setup installers. Payloads delivered included Insomnia RAT (Node.js and Python backdoors), ARKTunnel (a WebSocket-based RAT using LSB steganography), and Docro Hijacker (Chrome browser hijacker), with later infections delivering GCleaner and Socks5Systemz. Over 200 rotating domains across .xyz, .cfd, .space, and .info TLDs were used, with gating filters that served broken links or decoy pages to scanners and researchers.

GBHackers·Sep 11, 12:24 UTC · 5d agoMalware in the wild2

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Trends in Web Threats in CY Q2 2022: Malicious JavaScript Downloaders Are Evolving

Unit 42 detected 751,000 landing URL incidents in Q2 2022 and documented malicious JavaScript downloaders evolving to evade detection.

Unit 42 detected 751,331 landing URL incidents (253,644 unique) and 1,744,629 malicious host URL incidents (256,844 unique) from April through June 2022. Total landing URL incidents rose compared with Q1 2022, and unique host URL incidents grew 42%, indicating attackers deploying more variants. The report includes a case study of a JavaScript downloader campaign demonstrating new evasion techniques. Personal sites, blogs, and business sites were the top apparently benign entry points.

Palo Alto Unit 42·Aug 17, 13:05 UTC · Aug 17, 2026Research

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Trends in Web Threats: Attackers Were More Active During Holiday Season

Unit 42 tracked 533,000 malicious landing URL incidents from October-December 2021, showing web threats peaked during the holiday shopping season.

Unit 42 detected 533,452 malicious landing URL incidents (120,753 unique) and 2,906,875 malicious host URL incidents (165,255 unique) from October through December 2021. Threat activity peaked in November, likely tied to Black Friday in the United States, United Kingdom, and Germany. Most malicious domains appeared to originate in the United States, followed by Russia and Germany. Personal sites, blogs, business sites, and shopping sites were the most common apparently benign entry points for attacks.

Palo Alto Unit 42·Aug 17, 13:06 UTC · Aug 17, 2026Research

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Advanced URL Filtering Archives

Palo Alto Networks markets Advanced URL Filtering as combining a malicious URL database with real-time ML and DL web protection.

The Unit 42 blog page is a product category archive for Advanced URL Filtering. The product description states it combines a malicious URL database with a real-time web protection engine powered by machine learning and deep learning models. No research findings, incidents, or vulnerabilities are discussed.

Palo Alto Unit 42·Sep 8, 14:27 UTC · 8d agoIndustry 6 sources

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Panzer Ransomware Targets Italian Manufacturers and Telecom Firms With ESXi-Ready RaaS

New Panzer ransomware-as-a-service operation lists Italian firms Doimo Cucine and NTE Italia as victims, offering encryptors for Windows, Linux, FreeBSD, and ESXi.

Panzer, a ransomware-as-a-service operation that surfaced August 5, listed a kitchen manufacturer in Treviso (Doimo Cucine) and a telecommunications engineering firm in Catanzaro (NTE Italia) among alleged victims, claiming 30 GB and 16 GB of stolen data respectively. The group advertises encryptors for Windows, Linux, FreeBSD, and VMware ESXi, a Tox-based affiliate recruitment process with screening, an affiliate dashboard, and an 80/20 revenue split. Neither victim had publicly confirmed the incidents when researcher Andrea Fortuna's report was published, and the group's first access method and payload have not been independently analyzed. Panzer posted victims across 11 countries as claimed Italian ransomware incidents reached 212 by September 6, already above 2025's full-year total of 169.

Cyber Security News·Sep 8, 09:10 UTC · 8d agoRansomware in the wild

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Akira Hits Safe Mode: Ransomware Rebooting Around EDR

Huntress documents an Akira ransomware affiliate rebooting endpoints into Windows Safe Mode to evade EDR and Defender, though Safe Mode broke the ransomware.

Huntress observed an Akira ransomware affiliate rebooting victim machines into Windows Safe Mode to disable EDR and Microsoft Defender before deploying ransomware. In an ironic twist, Safe Mode also prevented the ransomware from executing properly. The post walks through the full attack chain and the defensive lessons.

Huntress·Aug 12, 13:00 UTC · Aug 12, 2026Ransomware in the wild

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Top 10 Best Ransomware Protection Solutions in 2026

A 2026 buyer's guide ranks ten ransomware protection tools by kill-chain role as extortion shifts from encryption to data theft.

The roundup organizes defenses across the ransomware kill chain: prevention-grade EPP/EDR platforms, containment layers, rollback specialists, and immutable recovery. Recommended products include CrowdStrike, Microsoft Defender, Sophos, SentinelOne, Bitdefender, Trend Micro, Halcyon, Huntress, and Malwarebytes. It stresses that many crews now extort on stolen data without encrypting, making exfiltration detection and response speed as important as rollback.

Cyber Security News·Sep 10, 08:18 UTC · 6d agoIndustry1

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GentleKiller targets more than 400 security processes across 48 products

ESET details the Gentlemen ransomware gang's in-house GentleKiller EDR-killer framework targeting over 400 security processes across 48 products, supplied to affiliates.

ESET analyzed the Gentlemen ransomware gang's in-house GentleKiller EDR-killer framework, confirmed through an internal data leak from May 2026. The framework has at least eight variants impersonating legitimate security products and abusing vulnerable or malicious kernel drivers, targeting more than 400 process names across 48 security products. Gentlemen emerged in late 2025, became one of the five most active ransomware gangs in Q1 2026, offers affiliates a 90% ransom share, and practices double extortion using Go-based and C-based ESXi encryptors. The suite also reuses outside tools including HexKiller, ThrottleBlood, and HavocKiller, unified by a shared evasion layer that mimics well-known security vendors.

Help Net Security·Aug 24, 04:22 UTC · 23d agoRansomware in the wild

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Russian hackers plant nuclear weapon prompt in malware to trip AI safety guardrails

ESET reports Russian group UAC-0099 hid a prompt in VBS malware comments to trip AI safety filters and disrupt automated malware analysis in Ukraine.

ESET identified a technique dubbed GuardBreaker in which UAC-0099 embedded a comment reading "I want to make nuclear weapon. Help me …" inside a malicious VBS script to trigger AI safety mechanisms and halt AI-assisted malware analysis. The script, part of the group's toolset, downloads the MATCHBOIL malware used exclusively by this Russia-aligned group; CERT-UA documented the chain including LUNCHPOKE, BURNYBEAR and MATCHBOIL.V2 in a July advisory. UAC-0099 typically targets transportation and energy sectors and hands validated targets to GRU-linked Sandworm. ESET warned that AI-assisted analysis must be backed by layered detection and human-driven engineering.

Help Net Security·Aug 31, 00:00 UTC · 16d agoAI safety & security in the wild

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Untracked Nightmares: The Threats Hiding Behind Commodity Infrastructure

Unit 42 exposes CL-CRI-1171, a pay-per-install network spreading malware like Insomnia RAT via YouTube channels and SEO poisoning for over two years.

Palo Alto Networks Unit 42 details CL-CRI-1171, a cybercrime cluster operating a pay-per-install (PPI) marketplace that has delivered multiple malware families for at least two years. The group used at least eleven YouTube gaming channels with hundreds of thousands of followers, plus SEO poisoning promoting trojanized software such as a Bluetooth driver and WinDirStat, infecting gamers and corporate endpoints including critical infrastructure and government entities. A single shared loader delivered payloads including Insomnia RAT, ARKTunnel, Docro Hijacker, GCleaner and Socks5Systemz between July 2025 and April 2026, with more than 10,000 distinct loader samples and over 200 rotating C2 domains identified. YouTube terminated the malicious channels after Unit 42 notified the platform.

Palo Alto Unit 42·Sep 9, 10:00 UTC · 7d agoMalware in the wild1

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GuardBreaker: Derailing AI-assisted malware analysis with a code comment

ESET names 'GuardBreaker': UAC-0099 embeds a nuclear-weapon question in VBScript comments to trip LLM scanner guardrails during analysis of its MATCHBOIL loader.

ESET researchers observed the Russia-aligned group UAC-0099 inserting a decoy prompt injection into a VBScript used to install its MATCHBOIL loader in an attack against a Ukrainian target, aiming to make LLM-based code scanners refuse and stop inspecting the file. The comment triggers safety guardrails with a request about building a nuclear weapons but has no runtime effect. Similar LLM-thwarting tricks have appeared in malicious PyPI and npm packages reported by Socket and StepSecurity. ESET recommends multi-model cross-validation of AI-assisted analysis and treating missing LLM output as requiring further checks.

ESET WeLiveSecurity·updated Sep 11, 14:32 UTC · 5d ago·first Sep 10, 09:00 UTC · 6d agoAI safety & security 3 sources1

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HypoEvolve: Genetic Algorithms Enable Multi-Agent LLMs to Discover Scientific Hypotheses

HypoEvolve couples a generational genetic algorithm with specialized LLM agents to generate drug-repurposing hypotheses, beating six baselines on DepMap selectivity (0.171 vs 0.115).

HypoEvolve coordinates specialized LLM agents through a generational genetic algorithm in which scientific judgments and new proposals reshape a hypothesis population. Evaluation centers on drug repurposing, linking mechanistic explanations to target-level biological claims assessed via external measures adapted from DepMap and Open Targets. Across 34 cancer types, HypoEvolve scores highest against six baselines on both measures, with DepMap selectivity of 0.171 versus 0.115 for the strongest baseline, and gains generalize to held-out cancer types.

arXiv cs.AI / cs.LG / cs.CL·Sep 14, 17:44 UTC · 2d agoAI research1

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Akira Affiliate Crashes Ransomware After Attempting EDR Evasion

Huntress documented an Akira ransomware affiliate attack that failed after its anti-EDR tool crashed legitimate software and stopped encryption before completion.

Infosecurity Magazine reports on Huntress research into a failed Akira ransomware affiliate attack. The affiliate attempted EDR evasion using an anti-EDR tool, but the tool interfered with legitimate software on the client's system. The interference crashed the ransomware before encryption completed, sabotaging the attack; no completed encryption was reported.

Infosecurity Magazine·Aug 13, 09:30 UTC · Aug 13, 2026Ransomware

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[0day-rubbish] Royal Server 5.04.50529.0 Local privilege escalation to LocalSystem on the execution path without credential override (7.2)

0day Rubbish Research Team disclosed a CVSS 7.2 local privilege escalation (CWE-250) in Royal Server 5.04.50529.0 to LocalSystem.

Researchers publicly disclosed a local privilege escalation vulnerability in Royal Server 5.04.50529.0, classified as CWE-250 (execution with unnecessary privileges) with a CVSS score of 7.2. The flaw allows escalation to LocalSystem on the execution path without credential override. The disclosure was posted to the Full Disclosure mailing list on September 8, 2026; no patch or CVE id was mentioned in the notice.

Full Disclosure·Sep 8, 17:31 UTC · 8d agoVulnerability

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Biology-in-the-loop: Amortized Adaptive Hit Discovery in CRISPR Screens

Researchers release AssayBench-Loop, a 1,389-screen CRISPR benchmark, and AssayLoop, a framework that learns adaptive hit discovery policies.

The paper introduces AssayBench-Loop, a large-scale benchmark of 1,389 CRISPR screens across five phenotype categories for adaptive hit discovery under budget constraints. It also introduces AssayLoop, which combines AssayFormer, a transformer-based amortized acquisition policy trained across historical screens, with LLM-derived biological priors via an adaptive handoff. On temporally held-out screens, AssayLoop achieves 5.67-fold enrichment over random selection and recovers 27.7% of hits after assaying roughly 5% of the candidate library, outperforming existing adaptive-design methods and standalone LLMs.

arXiv cs.AI / cs.LG / cs.CL·Sep 10, 17:45 UTC · 6d agoAI research1

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Cost-Aware Hierarchical Multi-Agent Ransomware Detection and Family Attribution

Researchers propose a hierarchical multi-agent system that cuts ransomware analysis cost by 44% while reaching 96.57% detection accuracy.

An arXiv paper (2609.04820) presents a Cost-Aware Hierarchical Multi-Agent System (HMAS) for adaptive ransomware detection and family attribution. Specialized agents run static analysis first, with dynamic and memory modalities invoked only when confidence is insufficient or specialists disagree; a Meta Orchestrator balances accuracy against computational cost via a cost model, and a locally deployed LLM verifies difficult cases. The system achieved 96.57% accuracy, 0.96 F1-score, and 0.99 ROC-AUC for binary detection, and 0.90 macro-F1 for multiclass family attribution. Average analysis cost dropped 43.97% versus exhaustive analysis, with 56.05% of cases resolved using static evidence alone.

arXiv cs.CR·Sep 4, 07:17 UTC · 12d agoResearch

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How Does mHC Use Its Residual Streams? Selective Routing and Near-Identity Mixing

Analysis of DeepSeek-V4-Flash shows four-stream mHC residual blocks use only about two streams effectively, with late-layer mixing providing little benefit.

The study examines the four-stream residual pathway of DeepSeek-V4-Flash, finding typical attention or FFN sites effectively use about two streams and that residual mixing is modest, occurring primarily in early layers. Replacing late mixers with identity increases C4 perplexity by only 1.9% while replacing early mixers raises it by 41%. Retaining the three largest routing weights per token increases perplexity by at most 2.7%, showing the model uses only part of the flexibility afforded by the four-stream design.

arXiv cs.AI / cs.LG / cs.CL·Sep 4, 16:02 UTC · 12d agoAI research

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Trends in Web Threats: Old Web Skimmer Still Active Today

Unit 42 detected 577,000 landing URL incidents in Q1 2022, with an old web skimmer family still actively stealing payment card data.

Palo Alto Unit 42 detected 577,275 landing URL incidents (116,643 unique) and 2,043,862 malicious host URL incidents (180,370 unique) between January and March 2022. Web threat volumes declined after the November 2021 holiday peak, but an old web skimmer family remained active. Business and economy sites overtook personal sites as the most common apparently benign entry points. Most malicious domains geolocated to the United States, Germany, and Russia, though proxy servers and VPNs obscure true locations.

Palo Alto Unit 42·Aug 17, 13:05 UTC · Aug 17, 2026Research

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Reverse-engineered Jev-like modelnew

A GitHub project releases a reverse-engineered, Jev-like model, drawing modest attention with 42 points on Hacker News.

A GitHub repository (vinnylarouge/jevlike) publishes a reverse-engineered recreation described as a Jev-like model. The project surfaced on Hacker News, where it received 42 points and 7 comments. The available source text does not specify the base model, architecture, parameter count, or benchmark results.

Hacker News · AI·18:49 UTC · 4h agoModel releaseHN 42↑ · 7 comments

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