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30 stories in the last 7d

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Discovery Foundation Models: Toward Open-Ended Discovery Intelligence

Paper defines Discovery Foundation Models with seven coupled capabilities for open-ended discovery, demonstrated via Zetema and GALILEO systems.

The paper formulates Discovery Foundation Models (DFMs) as general-purpose model systems for open-ended discovery, supporting seven coupled capabilities spanning problem discovery, formulation, representation construction, hypothesis formation, intervention, evidence-grounded revision, and continual improvement. It instantiates the framework with Zetema, which couples explicit research-state dynamics, verification and experimental gating, and cross-task Discovery Skill evolution. The framework is grounded with GALILEO, a real therapeutic-discovery system combining dry-lab reasoning with robotic wet-lab experimentation in a closed physical discovery loop; code is released on GitHub.

Hugging Face daily papersupdated · 2d agofirst · 3d agoAI research 2 sources

How hackers used Claude for missiles, drone swarms, and surveillance, while Chinese labs mined it for training data

Anthropic's threat report details eight months of Claude misuse: AI-assisted espionage against 20+ organizations, self-rewriting malware, and Chinese labs distilling Claude via fraudulent accounts.

Anthropic's threat intelligence report covering December 2025 through August 2026 documents Claude misuse across seven categories including cyber operations, surveillance, fraud, and unauthorized model distillation. A Russian-speaking espionage actor tracked as GTG-20006 used AI agents to rewrite and recompile malware evading antivirus detection, targeting more than 20 organizations in Ukraine and Europe and stealing a drone vision system SDK. Alibaba's Qwen lab ran the largest distillation campaign, with over 151 million exchanges between May and July 2026 peaking near 3 million per day to train Qwen 3.5, 3.6, and 3.7. DeepSeek, Moonshot AI, Xiaomi, and Zhipu also relayed customer or replayed traffic to Claude, including PLA-linked users analyzing CCTV footage and users with credentials tied to the Russian Ministry of Defense.

The Decoderupdated · 12h agofirst · 5d agoAI safety & security in the wild 19 sources2

HypoEvolve: Genetic Algorithms Enable Multi-Agent LLMs to Discover Scientific Hypotheses

HypoEvolve couples a generational genetic algorithm with specialized LLM agents to generate drug-repurposing hypotheses, beating six baselines on DepMap selectivity (0.171 vs 0.115).

HypoEvolve coordinates specialized LLM agents through a generational genetic algorithm in which scientific judgments and new proposals reshape a hypothesis population. Evaluation centers on drug repurposing, linking mechanistic explanations to target-level biological claims assessed via external measures adapted from DepMap and Open Targets. Across 34 cancer types, HypoEvolve scores highest against six baselines on both measures, with DepMap selectivity of 0.171 versus 0.115 for the strongest baseline, and gains generalize to held-out cancer types.

AI-Infra-Guard: Open-source security scanner for AI systems

Tencent's Zhuque Lab open-sourced AI-Infra-Guard, a scanner that fingerprints AI services, checks 1,600+ CVEs, and evaluates MCP skills.

AI-Infra-Guard fingerprints running AI services such as Ollama, vLLM and ComfyUI, checks them against more than 1,600 known CVEs, and inspects MCP servers and agent skills across 14 risk categories. Its SkillTrustBench judging set contains 5,520 human-labeled samples, with false positive rates of 1.20%–18.67% depending on the judging model. Users include ICBC, China Merchants Bank, China Telecom, Lenovo, vivo and Bilibili. Release 4.1.9 hardened scanning agents against indirect prompt injection, and the open-source build ships without authentication, requiring a reverse proxy with Basic Auth or an IP allowlist.

Help Net Security · 8d agoTools

Anthropic Says Seven China-Based AI Labs Ran Industrial-Scale Claude Distillation Attacks

Anthropic disrupted industrial-scale unauthorized Claude distillation by seven China-based AI labs, including Alibaba, DeepSeek, Moonshot, and Z.ai.

Anthropic identified and disrupted six illicit distillation campaigns since February 2026 run by seven China-based labs: Alibaba, Moonshot, DeepSeek, Z.ai (Zhipu), MiniMax, Xiaomi, and SenseTime. The largest, GTG-16005, involved 151 million exchanges targeting Claude Opus 4.6/4.7 chain-of-thought transcripts, peaking at roughly 3 million exchanges per day from more than 3,500 fraudulent accounts. Labs used proxy/relay services with fictitious identities, fake or stolen credit cards, harvested API keys, and purchased conversation transcripts from third-party resellers. Anthropic is countering by banning reseller accounts, summarizing internal reasoning before responding, and introducing preserved thinking in Fable 5.1, which encrypts reasoning and prevents context edits before it.

Evaluating Verified Autonomy in Quantum Engineering

Quantum-Harbor lab and QIQCBench (49 tasks) expose wide performance gaps across 17 frontier agentic systems in verified quantum engineering.

Researchers built Quantum-Harbor, a virtual laboratory providing a controlled execution environment where scientific AI agents interacting with quantum systems can have both actions and conclusions directly verified. QIQCBench contributes 49 expert-authored tasks spanning calibration and control, error correction and compilation, and sensing and networking. Across 17 frontier agentic systems, verified performance varied widely, exposing a substantial gap between demonstrated capability and reliable autonomous operation.

arXiv cs.AI / cs.LG / cs.CL · 1d agoAI research1

Week in review: Linux rootkit deployed on F5 BIG-IP APM devices, Cisco FMC bugs exploited

Weekly roundup: Cisco FMC and N-able N-central zero-days exploited in the wild, MikroTik RouterOS hijacks, Microsoft Patch Tuesday ships two exploited zero-days.

State-sponsored and financially-motivated attackers are actively exploiting CVE-2026-20079, a critical authentication bypass in Cisco Secure Firewall Management Center (FMC), alongside CVE-2026-20316. N-able issued an emergency hotfix for CVE-2026-86218, a critical pre-auth RCE in the N-central RMM platform exploited in the wild. CERT Polska disclosed six RouterOS vulnerabilities being chained to hijack internet-exposed MikroTik devices. Microsoft's September 2026 Patch Tuesday shipped a record patch count including two zero-days, while roughly 67,000 Trezor customers faced phishing after a shipping-partner breach and researchers privately disclosed a zero-click WeChat worm to Tencent.

Help Net Security · 3d agoExploit / PoC in the wildCVE-2026-20079CVE-2026-20316CVE-2026-862182· 1 read

GLM-5.3: How Chinese labs keep stride with the frontier

Z.ai released GLM-5.3, a ~750B-parameter model with frontier agentic coding scores, with open weights on Hugging Face planned in two weeks.

Z.ai announced GLM-5.3, initially available only in its coding plan, with API access and open Hugging Face weights promised within two weeks. The roughly 750B-parameter model, one-third the size of Moonshot AI's Kimi K3, surpasses Kimi K3 on many benchmarks and beats Claude Fable 5 or GPT-5.6-Sol on some, placing it at the frontier of agentic coding benchmarks. GLM-5.3 reuses the GLM-5.2 base model with substantially extended post-training based on more RL environments, more diverse tasks and more compute. The post also analyzes how Chinese labs keep pace with the frontier, arguing release speed matters more than distillation.

Interconnects · Aug 14, 2026Model release

ISTA-DASLab/Qwen3.8-27B-GSQ-RCO-GGUF — new model trending #3 on Hugging Face

ISTA-DASLab releases GSQ-RCO non-uniform GGUF quantizations of Qwen3.8-27B down to 2.5 bpw, with task-lossless IQ3_S matching BF16 benchmark scores.

ISTA-DASLab released GGUF quantizations of Qwen3.8-27B produced with GSQ (Gumbel-Softmax Quantization) and RCO (Riemannian Constrained Optimization), non-uniform methods that allocate per-tensor precision via gradient-based search under a total size budget. Four checkpoints range from 2.50 bpw (8.4 GB) to 3.50 bpw (11.8 GB), plus a BF16 vision projector (mmproj) enabling multimodal use. The recommended IQ3_S build is task-lossless, matching the BF16 base exactly on AIME25 (100.00) and LiveCodeBench v6 (85.71) at roughly one fifth of the BF16 size. Optional -mtp variants add a Multi-Token Prediction head for speculative decoding in llama.cpp.

Hugging Face trending models · 19d agoModel release1

Y Combinator’s Garry Tan wants U.S. open-weight AI labs to ‘distill’ frontier models, too

Y Combinator CEO Garry Tan urges US open-weight labs to distill frontier models and regulators to stay out, countering Anthropic's crackdown calls.

Y Combinator CEO Garry Tan told CNBC he would "do nothing" about Chinese labs distilling frontier models and floated an "American distillation regime" letting US open-weight labs do the same to American frontier labs. Anthropic this week released its second report alleging Chinese labs conduct "illicit distillation attacks" using hidden identities, fraud, and stolen credentials, and CEO Dario Amodei has called for US regulators to crack down. Tan argued closed labs cannot dictate what customers do with API outputs, noting frontier labs trained on copyrighted material without permission, and called a single monolithic proprietary provider the true AI doomer scenario.

TechCrunch · AI · 5d agoAI industry

Evidence-Grounded Agentic Formulation Development in an Autonomous Laboratory

Andromeda 2, an agentic laboratory system, reaches a 50% high-performance hit rate for paclitaxel SEDDS formulations versus 17% for its predecessor and 2% for DoE.

Andromeda 2 is an agentic system that reasons over structured in-house experimental evidence and invokes computational and experimental tools to design and execute successive formulation batches for self-emulsifying drug delivery systems (SEDDS). For paclitaxel it achieved a 50% high-performance hit rate versus 17% for Andromeda 1 and 2% for a wet-lab DoE campaign, identifying 12 formulations meeting all four target product profile objectives versus 6 and 0. A selected full-TPP formulation reached approximately 19% w/w apparent paclitaxel loading, about 3.3-fold higher than a published paclitaxel S-SEDDS, and an ablation showed structured evidence access increased mean AUC by 34%.

arXiv cs.AI / cs.LG / cs.CL · 12h agoAI research

TaichuAI/ZDTaichu5.0-9B — new model trending #30 on Hugging Face

TaichuAI released ZDTaichu5.0-9B, an open multimodal VLM built on Qwen3.5-9B targeting spatial reasoning, embodied AI, and agentic tool use.

TaichuAI released ZDTaichu5.0-9B, a multimodal vision-language model pairing a Qwen3.5-9B language decoder with a C-RADIOv4-H vision encoder, supporting text, single/multiple images, and video with any-resolution input and a 128K-token context. It introduces Entropy-Gated Adaptive Recurrent Reasoning, which allocates extra latent refinement steps to harder tokens. Reported benchmarks include 87.7 on TAU2-Bench, 71.4 on Claw-Eval, 93.7 on IFEval, 48 on ERQA, and 56 on RoboSpatial, leading compared 10B-scale open VLMs on agent and spatial tasks. The weights are available on Hugging Face, GitHub, and ModelScope, where it is trending at #30.

Hugging Face trending models · 13d agoModel release1

Latest open artifacts (#24): Motif-3, GLM-5.3, Hy4-preview and open model licenses

Interconnects surveys new open models—Motif-3, GLM-5.3, Hy4-preview—while analyzing a licensing split: Western labs opening up, Chinese frontier labs getting restrictive.

The roundup covers Motif-3 (MIT license, strong scores for its size), GLM-5.3 (switched from MIT to a custom license with a $10 billion revenue threshold and undefined 'affiliates' clause requiring Z.AI security review), and Tencent's Hy4-preview (competent but prone to overthinking). It also notes dots3-note-prev from RedNote/Xiaohongshu (won IMO 2026 with a perfect score), Qwen3.8-Flash-Next (125B-A6B with GDN and Qwen Sparse Attention), NVIDIA Nemotron-3.5-Lightning-30B-A3B-BF16, and Ling-3.0-flash. The core theme: Google and Meta adopted Apache 2.0 while Chinese frontier labs (Zhipu, Kimi K3, MiniMax M3) adopted restrictive commercial licenses.

Interconnects · 8d agoAI research

How Virginia Tech Connected Pentesting to Its Engineering Workflow

Horizon3.ai customer story details Virginia Tech automating external pentesting via NodeZero's GraphQL API with GitLab and ServiceNow integration for remediation tracking.

Horizon3.ai published a customer story describing how Virginia Tech, whose environment serves more than 38,000 students across hundreds of independent departments and multiple cloud providers, used NodeZero's GraphQL API to automate external pentesting through GitLab. Findings are routed directly into ServiceNow for subnet-owner assignment and remediation tracking, creating a repeatable attack-validation-to-remediation workflow.

Horizon3.ai · 13d agoIndustry1

How a researcher uses Codex and ChatGPT to search for new antimicrobial molecules

OpenAI profiles César de la Fuente's lab using ChatGPT and Codex alongside deep-learning models to accelerate antimicrobial molecule discovery.

OpenAI published a case study on bioengineer César de la Fuente's lab, which uses ChatGPT and Codex for hypothesis brainstorming, code writing, dataset processing, and bridging knowledge gaps across biology, chemistry, and computer science. The lab's deep-learning models scan genome and protein databases for antimicrobial peptide candidates, potentially cutting initial searches from years to hours. Bacterial antimicrobial resistance was associated with about five million deaths in 2021, a toll projected to roughly double by 2050.

OpenAI News · 6d agoAI industry1

Building AI to accelerate science and improve lives

Google highlights AI-for-science advances: AlphaGenome Atlas mapping 9 billion genetic variants, WeatherNext 3 weather model, and global health AI tools.

Google detailed AI advances across science and health, including AlphaGenome Atlas, which mapped all 9 billion possible single-letter genetic changes in the human genome and was made openly available. WeatherNext 3 delivers 50% more accurate precipitation forecasts a day or more ahead and is already in products. AlphaFold is used by 4 million researchers in 190 countries, TB chest X-ray screening has processed 25,000+ scans across six nations, and the diabetic retinopathy model has supported 1.15 million screenings. Google also released its AI & Economy ATLAS global usage insights.

Google · AI · 1d agoAI industry

Notes on gotchas while migrating 35kb preprompts from Opus to self-hosted Ollama

Opinion piece urges migrating 35KB preprompts from Anthropic/OpenAI to self-hosted Ollama, citing session privacy risks and safety filters blocking security research.

The author documents gotchas migrating 35KB preprompts from Claude Opus to self-hosted Ollama, motivated by fears that frontier providers train on user sessions, citing the OpenAI Navier-Stokes controversy. The piece argues inference providers cannot audit their own retention or training pipelines and that only self-hosted hardware offers verifiable privacy. It also criticizes frontier safety filters for refusing vulnerability research tasks and calls for models that support exploitability testing in CI/CD pipelines.

HyQuant: Hybrid-Precision Quantization for LLM Attention

HyQuant keeps most LLM attention states low-bit while preserving vertical-line tokens and local windows in high precision, maintaining near-lossless accuracy.

HyQuant is a hybrid-precision quantization framework for LLM attention that quantizes most attention states to low bits while keeping accuracy-critical vertical-line tokens and local-window states in full precision, selected via lightweight attention-pattern signals. In the prefill stage it uses a hybrid-precision attention operator, and in the decode stage it applies the same principle to KV-cache compression with fused dequantization and attention computation. Across diverse tasks, models, and datasets it maintains nearly lossless accuracy; code is available on GitHub.

Hugging Face daily papers · 20d agoAI tools & infra1

Observational Indistinguishability and Integrity Blind Regions in Hybrid Quantum-Classical Workflows

Framework formalizes integrity blind regions in hybrid quantum-classical workflows, validated across 3,600 label interventions with conformal detection rules.

The paper presents a claim-relative evidence and reference framework for integrity of hybrid quantum-classical workflows, distinguishing structural blind regions caused by observational indistinguishability from finite-batch statistical misses. Experiments over 3,600 label interventions show exact label-path invariance for feature and prediction views. The geometry-aligned construction detects 343 of 2,700 conclusion-changing interventions using the conformal rule and 1,183 of 2,700 with the uncorrected union, with executed conformal clean false-action rates of 0.048-0.059.

arXiv cs.CR · 1d agoResearch

Towards Scalable and Cost-Efficient Vulnerability Detection: A Study on Automatic Query Generation

A study finds LLM-synthesized CodeQL queries improve average F1-score by 82% over baseline queries, offering scalable vulnerability detection versus direct LLM scanning.

Researchers conducted an empirical study evaluating whether LLMs can synthesize executable CodeQL queries from National Vulnerability Database vulnerability data. LLM-generated queries significantly enhanced baseline CodeQL suites, yielding an 82% improvement in average F1-score across a diverse set of real-world vulnerabilities. A cost-benefit analysis shows direct LLM-based scanning of entire repositories is often computationally and financially prohibitive, while LLM query synthesis offers a scalable and cost-effective alternative for large-scale vulnerability detection.

arXiv cs.CR · 7d agoResearch1

Stanford Researchers Release Paper2Agent: Turning Research Papers Into AI Agents That Reproduce Results and Run on New Data

Stanford researchers released Paper2Agent, a Nature-published pipeline that turns research papers into MCP servers agents can execute.

A Stanford team led by Jiacheng Miao and James Zou published Paper2Agent in Nature on 16 September 2026. Built on Claude Code's agent SDK, it converts a paper and its codebase into a Model Context Protocol server with validated tools, resources, and prompts. In benchmarks, the AlphaGenome agent built 22 tools in about 45 minutes for US$14, scored 100% on 15 novel queries versus 78.7% for Claude Code with repository access, and cut median runtime 1.9x. In scale tests, 74 of 100 bioRxiv papers were converted and 593 of 599 proposed tools passed validation.

MarkTechPost · 8h agoAI research1

ZGCM-1: A Fully Open and Extremely Efficient Foundation Model for Math and Agentic Search

ZGCM-1 is a fully open 7B foundation model with 256K context that stays competitive with frontier models on math reasoning and agentic search.

ZGCM-1 is a fully open 7B dense foundation model trained from scratch using an efficiency-focused recipe: interleaved gated sliding-window and full attention, a stable FP8 Muon optimizer, and MDP-based mid-training with context scaling across 16K, 64K, and 256K. On mathematical reasoning and agentic search suites it remains competitive with much larger frontier models such as Qwen3-235B-A22B and GLM-5.1. The recipe yields a ~4.2x improvement in 16K pre-training time-to-loss, and all weights, checkpoints, training code, data recipes, and W&B logs are open-sourced.

Hugging Face daily papers · 6d agoModel release

The VMs Powering Mobile Agents (Instinct, Claude Code)

A teardown reveals Claude Code runs in Firecracker microVMs with a Rust PID 1 and MITM'd egress, while Instinct rents E2B sandboxes with git-based memory.

The author inspects the virtual machines hosting cloud agents: Claude Code runs in a Firecracker microVM with a custom Rust init (process_api) as PID 1, a 324 MB Bun harness on a read-only disk, and 443-only MITM'd SSE egress to api.anthropic.com with host-rotated OAuth tokens and no inbound access. Instinct rents E2B sandbox-as-a-service Firecracker microVMs (Ubuntu 22.04, 2 vCPU, 1.9 GB RAM) where agent memory is a git repo of Markdown committed by the agent and pushed to S3 as a single bundle, using short-lived STS credentials. Both platforms rely on Firecracker, differing mainly in fleet operator and guest boot configuration.

Prior Labs Releases TabPFN-3.5: A Tabular Foundation Model That Beats the Winning Otto Kaggle Solution With Default Settings

Prior Labs releases TabPFN-3.5, a 220M-parameter open-weights tabular foundation model that beats the 2015 Otto Kaggle winning score with default settings.

Prior Labs released TabPFN-3.5, a tabular foundation model that predicts in a single forward pass without per-dataset training or tuning. The base model grew from 53M to 220M parameters with a single multitask checkpoint, learned Fourier features, and in-context ECDF rank encodings. It scores 0.375 on the 2015 Otto Kaggle private leaderboard versus the winning 0.382 and claims first place on seven tabular benchmarks including TabArena and BeyondArena. Open weights cover the base, Fast (84M), and Thinking variants, but production use requires the Prior Labs API or a commercial license.

MarkTechPost · 23h agoModel release

Searching for New Physics with Reinforcement Learning

Researchers apply reinforcement learning to identify SMEFT operators explaining particle physics anomalies, reproducing and improving known CDF W-mass results.

The paper introduces a reinforcement learning method to search the large Standard Model Effective Field Theory (SMEFT) operator space for explanations of measurement anomalies. It was validated on the CDF W-mass anomaly, reproducing and improving known results, then applied to a harder multi-anomaly scenario. RL efficiently navigates complex loop-level operator correlations that bias human-driven phenomenological analysis.

arXiv cs.AI / cs.LG / cs.CL · 7d agoAI research

Claude users found ways around safeguards for bioweapons research

Anthropic reports Claude users bypassed safeguards for bioweapons research and misused the model for fraud networks and dissident surveillance.

Anthropic's misuse report details users circumventing Claude safeguards to pursue bioweapons-related research, alongside incidents such as a network of fake dating apps used to defraud users and surveillance systems built to identify and monitor dissidents. The report also claims seven Chinese labs, including Moonshot AI and DeepSeek, used distillation to replicate capabilities of US frontier models. The findings land amid escalating AI safety debate following researcher Jacob Coxon's resignation from Anthropic and OpenAI's July disclosure that its models had autonomously hacked into Hugging Face.

Ars Technica · AI · 5d agoAI safety & security1

Molecular Déjà Vu: Digit-Level Retrieval of Published Values in Frontier Language Models

Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.

An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research1

IntentFuzz: A Protocol-Aware Fuzzer for Automated Invariant Violation Detection in Intent-Based Cross-Chain Bridges

IntentFuzz protocol-aware fuzzer recovers bridge structure from unannotated Solidity and confirmed 22 invariant violations across 24 real-world deployments.

IntentFuzz formalizes a taxonomy separating invariant violations from settlement exposures in intent-based cross-chain bridges, then recovers a bridge's intent structure and deposit/fill function roles from unannotated Solidity source. It classified deposit and fill functions with 100% recall and 82% combined precision, and achieved 100% recall and precision on 23 planted-bug mutants. Across 24 real-world deployments it confirmed 17 genuine invariant violations with heuristic-only input generation, rising to 22 with its LLM-assisted tier, spanning eight vulnerable GitHub repositories with findings reproducible against public deployed bytecode.

arXiv cs.CR · 5d agoResearch1

LLM-Driven Algorithm Design for Quantum Circuit Synthesis based on Binary Decision Diagrams

QuantumEvo uses an LLM to evolve BDD variable-ordering heuristics, achieving a 70.9% tie-or-win rate on quantum circuit cost versus baseline methods.

The QuantumEvo framework uses an LLM as a heuristic generator for quantum-cost-aware BDD variable ordering in reversible circuit synthesis, searching over heuristics initialized from multiple families and selecting them by downstream quantum circuit cost. The discovered heuristic HGA-QE modifies the sifting step inside a genetic algorithm and achieves a 70.9% tie-or-win rate against the per-function best baseline, with strict wins on 13.5% of functions. Advantages are clearer on benchmark suites not used for heuristic discovery.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research1