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Palo Alto Networks positions Cortex XSIAM as a purpose-built platform to simplify security operations and speed incident remediation.
The Unit 42 blog page is a product category archive for Cortex XSIAM. The platform is marketed as purpose-built for SecOps transformation, simplifying security operations and accelerating incident remediation against current and future threats. No research findings, incidents, or vulnerabilities are discussed.
Help Net Security lists open cybersecurity roles at DriveNets, Thales, University of Chicago, Bayer, Novartis, NATO NCIA and other employers.
This is a recurring roundup of open cybersecurity job postings across multiple countries, including application security, cloud security architecture, red teaming, PKI and cryptography, and AI compliance governance roles. Listings span Israel, Canada, the USA, India, Ireland, the UK, Belgium and Australia. All positions shown are marked as no longer accepting applications.
Insilico Medicine's AI-designed drug rentosertib showed reduced predicted biological age in IPF trial blood analysis, published in Nature Biotechnology.
Insilico Medicine reported that rentosertib, an AI-designed drug candidate in Phase III trials for idiopathic pulmonary fibrosis, showed reduced predicted biological age in blood protein analysis of 42 trial patients. Six independent aging-clock models built by teams at Harvard, Oxford, Beijing, and Insilico all predicted lower biological age versus placebo, with drops of three to four years by week 4 and up to six years on one clock. The drug targets TNIK and was developed with two generative AI systems in about 18 months; Eli Lilly recently invested in the company. Experts including Eric Topol and Harvard's Vadim Gladyshev called the results encouraging but not definitive, citing small sample size.
ModaLens image-swap audit shows report availability cuts MedGemma-27B image sensitivity on MIMIC-CXR from 20.94% to 4.26% answer changes.
ModaLens is a paired image-swap audit measuring how report availability affects image sensitivity in report-conditioned medical VLMs. On MedGemma-27B across 3,199 paired MIMIC-CXR cases from 293 patients (14 questions per case), generated answers changed on 4.26% of image-swap trials with the report versus 20.94% without it, a 16.7-point paired difference (95% CI 15.6-17.7). The original prompt with a lowercase first-token readout gave 4.70% versus 17.07%, and the direction replicated in two further model lineages. Labels derived from reports limit conclusions about visual correctness; code, prompts, and run records are publicly released.
Study finds zero-shot time-series foundation models underperform on CGM forecasting; fine-tuned Chronos-Bolt cuts RMSE up to 18.4% and dietary context adds signal.
The paper evaluates time-series foundation models for continuous glucose monitoring forecasting across eight public datasets covering Type 1 diabetes, Type 2 diabetes, and non-diabetes populations. Under a unified protocol, zero-shot foundation models did not consistently outperform baselines like Elastic Net and PatchTST, but lightweight fine-tuning did, with fine-tuned Chronos-Bolt reducing RMSE by 6.5%-18.4% in the T1D cohort and 8.6%-18.2% in the non-diabetes/T2D cohort. A residual-based fusion framework adding dietary context from CGMacros reduced overall RMSE by about 3% and postprandial RMSE by about 15% versus CGM-only baselines.
LongAgent autonomously searches variable sets and temporal windows to predict longitudinal medical outcomes, beating the strongest non-agent baseline on synthetic data.
The paper proposes LongAgent, an agent-based method that searches over combinations of variable sets, temporal windows and aggregation functions for outcome prediction on heterogeneous medical longitudinal data. It uses a history memory of previous searches and numerical evidence to guide exploration. On synthetic data it achieves mean RMSE 1.7376, improving over the best non-agent baseline by 0.0151 (95% CI [0.0045, 0.0260]; p=0.0273), and performs comparably to the best baseline on a real clinical dataset.
HypoEvolve couples a generational genetic algorithm with specialized LLM agents to generate drug-repurposing hypotheses, beating six baselines on DepMap selectivity (0.171 vs 0.115).
HypoEvolve coordinates specialized LLM agents through a generational genetic algorithm in which scientific judgments and new proposals reshape a hypothesis population. Evaluation centers on drug repurposing, linking mechanistic explanations to target-level biological claims assessed via external measures adapted from DepMap and Open Targets. Across 34 cancer types, HypoEvolve scores highest against six baselines on both measures, with DepMap selectivity of 0.171 versus 0.115 for the strongest baseline, and gains generalize to held-out cancer types.
Boston Scientific says a cyberattack has caused global disruption to its operations, with no confirmation yet on device impact or data exfiltration.
Boston Scientific, a major medical device manufacturer, disclosed that a cyberattack is causing global disruption to its operations. The company has not confirmed whether medical devices are affected or whether any customer data was exfiltrated. The investigation appears to be ongoing, and healthcare-sector exposure raises patient-safety and supply-chain concerns.
The 2026 PNPL competition releases LibriBrain100, a MEG speech dataset with 32 extra subjects, targeting word classification and cross-subject BCI generalization.
The 2025 PNPL competition on non-invasive speech decoding from MEG achieved F1-macro scores of 95.6% for speech detection and 73.6% for phoneme classification, built on LibriBrain's ~50 hours of single-subject data. The 2026 edition extends this with LibriBrain100, adding 32 subjects (~40 minutes each) plus ~80 hours of within-subject data. Two tracks target within-subject word classification at scale and cross-subject generalization with subject-specific fine-tuning shrinking from ~40 to ~20 to ~10 minutes, aiming at clinically feasible non-invasive BCIs for people with profound paralysis.
Manufacturer-built backdoor implants were found in ZBT white-label routers sold worldwide, exposing affected devices to potential unauthorized access.
An untold number of ZBT routers distributed globally as white-label products contain multiple backdoor implants built into the devices by the manufacturer. The implants are pre-installed through the hardware and firmware supply chain rather than injected by attackers after deployment. The scale of affected deployments and whether the implants have been actively abused have not been disclosed.
Researchers introduce NOAH, a time-aware generative transformer trained on 559 million MIMIC clinical events to forecast multimodal patient trajectories.
NOAH is a task-agnostic, time-aware generative transformer trained on over 559 million clinical events from 431,000 hospital visits by 299,000 patients across the MIMIC dataset family. It uses bidirectional time integration and a variational latent space to model the stochastic evolution of patient states, natively processing medical images, time-series signals, categorical events, and structured or unstructured clinical records. The model supports autoregressive forecasting with optional time control, zero-shot classification, and counterfactual intervention simulation, with strong probing performance across clinical outcomes, 15 ICD chapters, and 29 comorbidities.
Proposes Discovery Foundation Models that participate in creating new problems and knowledge, instantiated in Zetema and the GALILEO therapeutic-discovery system.
The paper formulates Discovery Foundation Models (DFMs) as general-purpose systems for open-ended discovery, supporting seven coupled capabilities from problem discovery through evidence-grounded revision and continual improvement. It instantiates the framework with Zetema, combining explicit research-state dynamics, verification gating, external grounding, and cross-task Discovery Skill evolution. GALILEO, a real therapeutic-discovery system, closes the loop between Dry-Lab reasoning, robotic and hands-on Wet-Lab experimentation, and iterative hypothesis revision. The authors also define process-centered evaluation so discovery behavior can be trained and measured beyond final answers.
Palo Alto Networks publishes a product category page for Cortex Cloud, an AI and automation platform for cloud and SOC workflows.
This item is a product category archive page for Palo Alto Networks' Cortex Cloud, describing it as an AI and automation-driven platform spanning code to cloud to SOC. The page contains no new research, incident, or product release details beyond marketing language about prioritizing risks and accelerating remediation.
Palo Alto Unit 42 Cortex Xpanse product-category page published with no article text available for classification.
The URL resolves to the Cortex Xpanse product category listing on the Unit 42 blog rather than a research article. No article body was provided, so no vulnerabilities, incidents, or research findings can be extracted.
Researchers introduce NOAH, a generative time-aware transformer trained on 559 million MIMIC clinical events to model and forecast patient trajectories.
NOAH is a task-agnostic, time-aware generative transformer designed to represent and forecast the full multimodal patient journey across medical images, time-series signals, categorical events, and clinical text. It was trained on over 559 million clinical events from 431,000 hospital visits covering 299,000 patients in the MIMIC dataset family. The architecture combines bidirectional time integration with a variational latent space to capture continuous patient state evolution and clinical stochasticity. NOAH supports autoregressive forecasting with time control, zero-shot classification, and counterfactual intervention simulation, with evaluations on 15 ICD chapters, 29 comorbidities, and time-to-event prediction.
Clinician-calibrated K-Bench evaluates 125 LLM configurations on 200 high-risk mental health vignettes, exposing wide variation in suicide and violence risk handling.
K-Bench is a clinician-calibrated, protected benchmark evaluating 125 model configurations from 33 base models across 14 providers on 200 multi-turn vignettes covering suicide, self-harm, domestic violence, substance misuse and no-risk presentations. A frozen GPT-4o judge achieved 94.2% exact agreement with clinician consensus across 6,751 eligible comparisons from 151 clinician-rated transcripts. Leading models combined supportive conversation with combined-risk scores above 95, while risk exploration varied substantially among weaker configurations; therapeutic prompting helped weaker models and elevated reasoning produced no average improvement. A continuously updated public leaderboard is hosted at k-bench.ai with protected test materials.
Stub page for Palo Alto Cortex XDR with no article text, offering no news content for classification.
The item contains only the title 'cortex xdr' and no article body. It references Palo Alto Networks' Cortex XDR product but provides no event, release, or threat information. Classified as general vendor/industry content with minimal relevance.
Pharmaceutical giant McKesson disclosed a cyberattack on a third-party application that exfiltrated customer data, claimed by ShinyHunters.
McKesson reported a cybersecurity incident involving an unnamed third-party application, with attackers exfiltrating data tied to its oncology and surgical business units. The company filed with the SEC, offered credit monitoring, and said it had received reasonable assurance the attackers were no longer inside its systems. The ShinyHunters group claimed responsibility and threatened leaks; McKesson reported $106 billion in revenue last quarter and distributes about one-third of North American prescriptions.
Zscaler ThreatLabz analyzes Abyssos, a new modular C++ RAT offering credential theft, file exfiltration, and VNC-based remote access.
Zscaler ThreatLabz identified a new malware family tracked as Abyssos in late June 2026. Abyssos is a modular remote administration tool (RAT) written in C++ that supports credential theft, file exfiltration, and remote access via VNC. The malware is under active development, with multiple version numbers and obfuscation passes designed to evade security products. The analysis covers its core features, configuration, obfuscation, and network communication protocol.
Cortex XDR threat hunters uncovered a phishing campaign delivering the NetSupport Manager RAT via a fake password-protected NortonLifelock Word document.
Unit 42 identified a January 2020 phishing campaign using a Microsoft Word document disguised as a password-protected NortonLifelock file. Enabling macros triggered an obfuscated command that built alpaca.bat in the temp directory, which used msiexec to download an MSI payload from quickwaysignstx.com, filtered on the Windows Installer user-agent string. The payload installed a PowerShell script and the campaign, which has delivered NetSupport Manager RAT since at least 2018, showed related activity dating back to early November 2019.
Boston Scientific says its August 25 network intrusion will materially hit third-quarter and full-year sales and earnings, likely missing guidance.
Boston Scientific detected unauthorized activity on its network on August 25 and took systems offline, disrupting order processing and shipping operations worldwide. In an SEC filing, the medical device maker warned of a material impact on Q3 and full-year results, making it unlikely to meet the net sales growth and adjusted EPS guidance issued in July. Its distribution network has been substantially restored, sterilization facilities are operational, manufacturing resumed at most sites, and an interruption affecting cardiac device remote-monitoring activations was resolved. The company has not revealed the attack vector, whether ransomware was involved, or whether data was stolen; no ransomware group has claimed responsibility and the investigation continues.
Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.
An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.
ZDI detailed an uninitialized memory flaw in Oracle VirtualBox's VirtioSCSI (CVE-2026-71132) allowing local attackers to disclose sensitive information.
Zero Day Initiative published ZDI-26-640, a CVSS 5.3 information disclosure vulnerability in the VirtioSCSI component of Oracle VirtualBox. An attacker must first run high-privileged code on the guest system before the uninitialized memory issue can be used to disclose sensitive information. The flaw is tracked as CVE-2026-71132. The advisory reports no exploitation activity.
Study quantifies DPO-tuned LLMs undershooting requested emotional intensity, tracing the gap to candidate-pool extremity rather than conditioning format.
Conditioning an instruction-tuned LLM on continuous valence-arousal targets yields gain of only 0.26 for valence and 0.13 for arousal on Llama-3.1-8B, far below faithful control of 1.0. The authors attribute undershoot to neutral-heavy preference corpora like EmoBank and candidate pools lacking extreme affect, leaving DPO without extreme exemplars. Uniform target coverage with a hotter candidate pool raises valence gain to 0.40 on Llama-3.1-8B and 0.44 on Qwen3-8B, with modest in-distribution cost; arousal gains remain unstable across seeds.
Boston Scientific disclosed a cyberattack that caused a network outage, disrupting global operations including order processing and shipping.
The medical device maker detected the incident on August 25, activated incident response protocols with third-party cybersecurity experts, and told the SEC that access to systems supporting operations, including order processing and shipping, was disrupted. Boston Scientific employs about 59,000 people across 127 countries and posted more than $20 billion in net sales in 2025; it has not determined whether the incident is material and no group has claimed responsibility. The company joins a recent run of medtech attacks including Stryker, iRhythm, Novo Nordisk and Xsolis.
McKesson confirms a data breach as ShinyHunters demands $55.2M amid healthcare cyberattacks affecting millions of patient records and pacemaker devices.
McKesson, one of the largest US healthcare distribution companies, has admitted a data breach. The ShinyHunters group is demanding a $55.2M extortion payment. The Register reports broader healthcare cyberattacks tied to the story, affecting millions of patient records and involving medical devices such as pacemakers. Details on the exact number of compromised records have not been confirmed.
Clinical AI system Doctorina achieved 82.0% primary-care diagnostic concordance versus 57.0% for physicians across 150 synthetic consultations.
The study compared Doctorina, eight physicians, and four standalone frontier language models on 150 synthetic Polish-language primary-care consultations. Doctorina achieved 82.0% Top-1 diagnostic concordance versus 57.0% for physicians (25.0-point difference, 95% CI 17.7-32.7) and 97.3% versus 85.0% primary-or-reference-differential concordance. Normalized workup and treatment scores were 89.4 versus 66.9 and 83.7 versus 61.2. Kimi K3 ranked next on diagnosis, while Claude Opus 5 led the closely spaced management estimates among Opus, Doctorina and Kimi.
Researchers release DianShi-RxnDB, a database of roughly 24 million organic reaction instances extracted automatically from USPTO and EPO patents since 1976.
DianShi-RxnDB is built by a fully automated pipeline integrating patent text, images, and reaction schemes, yielding about 24 million reaction instances, of which 14.8 million (61.7%) pass automated qualification checks. Manual evaluation of 1,300 sampled instances showed 92.95% field-level accuracy, and comparisons with Pistachio found advantages in deduplicated record counts and granularity. The platform offers a web research workbench and a Model Context Protocol (MCP) service enabling AI agents to perform composable structured retrieval.
Dark Atlas details THost9, a packed Android RAT paired with an ADB worm that installs itself on devices with exposed Android Debug Bridge services.
Dark Atlas researchers described the Hagaseca cluster, whose THost9 packed loader hides executable code in an embedded asset decoded with single-byte XOR and gzip before loading a tc9.dex second stage. The second stage adds shell execution, file transfer, tunneling, reverse shells, downloadable modules and a self-propagating ADB worm that expands single addresses into 65,025-host scan ranges. Newer builds include anti-analysis checks for Frida, and incident reports connect THost9 and THost4 to Android phones and Redroid containers with exposed ADB from October 2024 through 2026.