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AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

Google DeepMind released AlphaGenome Atlas, a free 1-petabyte platform predicting the molecular effects of all ~9 billion possible single-letter DNA variants.

Google DeepMind introduced AlphaGenome Atlas, containing precomputed predictions for the effects of roughly 9 billion single-nucleotide variants across the human genome, spanning hundreds of human and mouse cell types. The 1-petabyte dataset is more than 30 times larger than the AlphaFold Database and includes an AlphaGenome Variant Impact (AVI) score combining AlphaGenome and AlphaMissense predictions for both coding and non-coding regions. External collaborators have already used it to identify and experimentally verify variants in unsolved rare disease research. It is available via a free web portal, the AlphaGenome API, and as a skill in Google Antigravity.

Google DeepMind · 8d agoAI research 2 sources

Hackers publish thousands of drivers’ data after breaching Florida motor vehicle database

ShinyHunters published hundreds of thousands of records from Florida's DAVID vehicle database, including SSNs and passports, after an unpaid ransom demand.

The ShinyHunters group published hundreds of thousands of files from Florida's DAVID motor vehicle database on its leak site, saying the victim did not pay a ransom. Stolen records include vehicle ownership certificates with names, addresses, and VINs, plus a smaller number of Social Security numbers, non-US passports, and immigration documents. FLHSMV confirmed the breach, which followed theft of a police officer's credentials stored on a personal device. It comes the same month as the IDScan hack exposing over 150 million driver's license images.

TechCrunch · Security · 2h agoData breach 3 sources

The Future of Deepfakes and the Decline of Reality (With Hany Farid)

GetReal cofounder and PhotoDNA developer Hany Farid discusses deepfake detection and how AI-generated media is blurring perceptions of reality.

404 Media's podcast episode features Hany Farid, cofounder of deepfake detection company GetReal and developer of the PhotoDNA perceptual hashing algorithm, discussing deepfakes and AI-generated images. The conversation reflects on how the technology has evolved since 2017 and speculates on where detection and perceptions of reality are headed. The episode is part of 404 Media's interview series for subscribers.

404 Media · Aug 17, 2026AI safety & security

ICE Collecting DNA Samples

ICE's DNA collection program projects detainee samples to reach 33% of CODIS offender index by 2030, raising privacy concerns.

A Schneier on Security blog post discusses ICE collecting DNA samples from detainees, citing Georgetown Law research. DHS detainee samples are projected to constitute 33% of the FBI's CODIS offender index in 2030, up from 0.2% in 2019. The post raises concerns that samples collected under civil authority are being searched against crime scenes indefinitely, potentially without legal cause under Fourth Amendment standards.

Schneier on Security · 28d agoPolicy & legal

Testing race conditions with memory access tracing and stack-based delay injection

Google Project Zero released MAccConc, Linux kernel tooling that traces memory accesses to explore and test race condition interleavings.

A Google Project Zero researcher published MAccConc (Memory Access Concurrency), tooling for exploring possible interleavings of multithreaded test cases in the Linux kernel, available on GitHub. The tools use KCOV with ASAN outline-mode instrumentation to record per-access memory traces, enabling automatic testing of all A-B-A interleavings plus terminal and GUI explorers for manual analysis. The work targets confirming race condition candidates, building reliable regression tests, and enabling concurrency fuzzing, drawing on ideas from SKI and Ned Williamson's sockfuzzer.

Google Project Zero · 8d agoResearch1

Molecular Déjà Vu: Digit-Level Retrieval of Published Values in Frontier Language Models

Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.

An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research1

Google DeepMind Releases AlphaGenome Atlas With Precomputed Molecular Effect Predictions and AVI Scores for 9 Billion Human DNA Variants

Google DeepMind launched AlphaGenome Atlas, precomputing molecular effect predictions and AVI impact scores for ~9 billion human single-nucleotide variants in a 1-petabyte catalogue.

Google DeepMind released AlphaGenome Atlas, a 1-petabyte catalogue of precomputed molecular effect predictions for roughly 9 billion possible single-nucleotide variants in the human genome. It introduces the AlphaGenome Variant Impact (AVI) score, combining AlphaGenome regulatory predictions with AlphaMissense, plus per-variant feature attributions and over 2,500 recurrent DNA sequence motifs. DeepMind reports best-in-class AVI performance on variant pathogenicity and rare disease benchmarks. Early users at the Broad Institute, University of Exeter, and Stowers Institute demonstrated rare-disease variant reprioritization and 22% more non-coding associations across 54,000+ UK Biobank genomes.

MarkTechPost · 8d agoAI research2

Can Edge-Deployable Vision-Language Models Identify Species?

Evaluation of 2-8B VLMs (Qwen3-VL, Gemma3) against BioCLIP on camera-trap species ID shows all models degrade sharply on field imagery.

The study tests whether edge-deployable 2-8B vision-language models carry genuine taxonomic knowledge, comparing Qwen3-VL 2B/4B/8B and Gemma3 4B against the 300M specialist BioCLIP on a 96-species task across clean iNaturalist photos and six LILA.science camera-trap collections. All models degrade 9.6-26.6 percentage points on field imagery, and BioCLIP outperforms every VLM by 33.2-59.2 points on an expanded 200-image sample, suggesting specialized data rather than scale drives the gap. Under open-set prompting, 5.9-9.6% of responses are syntactically valid but taxonomically nonexistent species names, with fabrication rankings replicating across evaluation sets.

arXiv cs.AI / cs.LG / cs.CL · 6d agoAI research1

ModaLens: Measuring Image Sensitivity in Report-Conditioned Medical VLMs

ModaLens image-swap audit shows report availability cuts MedGemma-27B image sensitivity on MIMIC-CXR from 20.94% to 4.26% answer changes.

ModaLens is a paired image-swap audit measuring how report availability affects image sensitivity in report-conditioned medical VLMs. On MedGemma-27B across 3,199 paired MIMIC-CXR cases from 293 patients (14 questions per case), generated answers changed on 4.26% of image-swap trials with the report versus 20.94% without it, a 16.7-point paired difference (95% CI 15.6-17.7). The original prompt with a lowercase first-token readout gave 4.70% versus 17.07%, and the direction replicated in two further model lineages. Labels derived from reports limit conclusions about visual correctness; code, prompts, and run records are publicly released.

Hugging Face daily papers · 3d agoAI research

Cops Search Thousands of Flock Cameras for Reasons of ‘LMAO,’ ‘IDK,’ ‘Hehe,’ and ‘asdfg’

EFF analysis found police searched Flock's 19,000-camera ALPR network using joke reasons like 'LMAO' and 'idk,' exposing routine warrantless surveillance abuse.

An EFF analysis of Flock audit logs, shared with 404 Media, found officers across dozens of jurisdictions searching over 19,000 cameras in 1,558 cities with justifications like 'LMAO,' 'idk,' and keyboard gibberish between 2023 and late 2025. One Lake County, Indiana sheriff's deputy searched for a license plate across the entire network citing 'LMAO.' After outlets exposed searches targeting ICE detainees, an abortion patient, and protesters, officers were reportedly told to be 'as vague as permissible,' and Flock replaced the free-text reason box with a prepopulated drop-down list, which EFF called a loss for transparency. Departments rarely disciplined offending officers, and EFF concluded agencies cannot oversee themselves.

404 Media · 2d agoPolicy & legal

Deepmind's AlphaGenome Atlas maps every possible DNA change in the human genome

DeepMind's AlphaGenome Atlas precomputes impact predictions for ~9 billion human DNA variants in a 1-petabyte dataset; its AVI score beats CADD in benchmarks

Google DeepMind released the AlphaGenome Atlas, precomputing functional-effect predictions for roughly 9 billion human genome variants (about 27,000 prediction values per variant) in a one-petabyte dataset more than 30 times the size of the AlphaFold database. The accompanying AlphaGenome Variant Impact Score (AVI), a small neural network combining AlphaGenome, AlphaMissense and evolutionary conservation features (18 inputs versus CADD's 150+), outperformed existing tools on clinically classified variants, ranking causal variants in the top 50 candidates for 29.5% of solved GREGoR cases versus 12.5% for CADD. A GREGoR epilepsy case illustrates the impact: AVI elevated a previously unclear DNM1 splice variant that lab experiments confirmed as likely disease-causing. The atlas is available for noncommercial use via web portal, API and a Google Antigravity skill, with a commercial version planned through Google Cloud.

The Decoder · 7d agoAI research

Fortunate Recall: Ontology-Driven Memory Lifecycle Management for Persistent Coherence in LLMs

Fortunate Recall introduces ontology-based lifecycle policies for LLM memory, cutting confabulation roughly in half (e.g., 45.1% to 22.4%) versus Mem0.

Fortunate Recall (FR) is a composable policy layer that classifies personal facts into a 10+1 behavioral ontology and applies category-specific lifecycle rules including differential temporal decay, slot-key supersession, event-time validity, and retrieval routing. FR-Bank scores 76.9% on the new 516-question LifecycleBench, ahead of Mem0, A-MEM, Memory-R1, and MemoryOS (61%-70.5%), and 75.2% on LongMemEval-S. End-to-end, confabulation drops from Mem0's 45.1% to 22.4% over answered queries, with the ranking replicating on open-weight Kimi K2.5 and transferring to the independent BEAM benchmark (46.8% vs 32.9%).

arXiv cs.AI / cs.LG / cs.CL · 7d agoAI research

Google's AI genome system evaluates every possible one-base change

Google's AlphaGenome AI system predicts functional effects of non-coding DNA variants in humans and mice.

Google's AlphaGenome AI system evaluates genomic sequences to predict gene expression, transcription factor binding, chromatin accessibility, splice site usage, and related genomic features. The system is currently limited to human and mouse sequences and a limited set of well-studied cell types, but its predictions generally match or exceed specialized software tools. Researchers can use it to assess whether non-coding variants are likely significant and generate hypotheses about their function.

Ars Technica · AI · 7d agoAI research

Automobile Camouflage to Hide from Flock Cameras

Schneier on Security highlights a printed vehicle-camouflage pattern tested to defeat Flock surveillance cameras and Axon body cameras.

The post discusses covering cars with printed patterns designed to fool Flock automated license-plate recognition software, with testing reportedly done against Flock and Axon body cameras. Reader comments question effectiveness against other ALPR vendors, Flock's RF MAC-address upgrade, and whether such camouflage might become regulated. The page also contains off-topic comment threads about anti-bot over-blocking and privacy.

Schneier on Security · 9d agoResearch

Google DeepMind Releases AlphaGenome Atlas

Google DeepMind released AlphaGenome Atlas, a 1-petabyte database pre-computing effects of all 9 billion single-nucleotide variants in the human genome, with a unified AVI score.

Google DeepMind launched AlphaGenome Atlas, a database that predicts the regulatory impact of every possible single nucleotide variant across the roughly 3 billion base pairs of the human genome, yielding a 1-petabyte dataset. It introduces the AlphaGenome Variant Impact (AVI) score, combining coding and non-coding predictions for rapid variant prioritization. Broad Institute researchers used it to support solving an unsolved rare disease case via a predicted DNM1 splice variant, and analysis of 54,000+ UK Biobank participants uncovered 22% more non-coding genetic associations, including 19 regions linked to BMI. The Atlas is available through a no-code web portal.

Hacker News · AI · 8d agoAI researchHN 44↑ · 4 comments

The 2026 PNPL Competition: Word Classification and Efficient Cross-Subject Generalisation in LibriBrain100

The 2026 PNPL competition releases LibriBrain100, a MEG speech dataset with 32 extra subjects, targeting word classification and cross-subject BCI generalization.

The 2025 PNPL competition on non-invasive speech decoding from MEG achieved F1-macro scores of 95.6% for speech detection and 73.6% for phoneme classification, built on LibriBrain's ~50 hours of single-subject data. The 2026 edition extends this with LibriBrain100, adding 32 subjects (~40 minutes each) plus ~80 hours of within-subject data. Two tracks target within-subject word classification at scale and cross-subject generalization with subject-specific fine-tuning shrinking from ~40 to ~20 to ~10 minutes, aiming at clinically feasible non-invasive BCIs for people with profound paralysis.

Hugging Face daily papers · 14d agoAI research

Texas Police Used AI to Write Report About Using Flock to Search for Woman Who Had Abortion

Johnson County, Texas deputies used Axon's Draft One AI to write a report about searching 80,000+ Flock cameras for a woman who self-administered an abortion.

Documents show the Johnson County Sheriff's Office used Flock's nationwide camera network and Axon's Draft One, which drafts police reports from body camera audio, in its investigation of a woman's self-administered abortion. The AI-generated report summarized deputies' discussion of legal implications, noting Texas law provided no applicable criminal charges. Flock CEO Garrett Langley has repeatedly claimed the search was a family welfare check, but earlier police reports indicate it was initiated at the behest of the woman's abusive partner.

404 Media · 14d agoAI safety & security

ShinyHunters claims Florida DMV breach, puts data on the clock

ShinyHunters claims it breached Florida DMV's DAVID database, stole 200,000+ driver records including SSNs, and set a September 11 extortion deadline.

The ShinyHunters extortion group claims it breached the Florida Department of Highway Safety and Motor Vehicles' DAVID driver and vehicle database and stole more than 200,000 records. As evidence it published a screenshot of a Jeffrey Epstein record showing address, Social Security number, date of birth, license number and registered vehicles, and set a September 11 deadline before publication. The group says it obtained access through a password-reset weakness, compromised employee accounts, and queried and downloaded driver records and images. The Florida DMV has not confirmed the claim; it follows a separate confirmed IDScan.net breach exposing over 153 million license scans that prompted an FBI investigation.

CSO Online · 7d agoData breach in the wild1

Flock camera use by internal affairs unit puts DC police at odds with officers’ union

DC's Metropolitan Police Department used Flock license plate cameras to track officers under internal affairs investigation, prompting a union grievance and council scrutiny.

The DC Police Union learned in July 2026 that MPD Internal Affairs used Flock ALPR cameras to monitor officers under investigation without their knowledge, filing a grievance that management denied. Secure Justice found more than 90 US cities and counties ended Flock contracts in August 2026 alone, with over 200 terminations since 2021, while Texas and Florida announced new usage restrictions. On September 14, DC Councilmember Brooke Pinto asked Interim Chief Jeffery Carroll ten questions about the department's use of Flock data.

The Record · 6h agoPolicy & legal

Fly Language Model (FLM) Wires the Full Fruit Fly Connectome Into a Frozen 1.2B LLM, and Its Own Controls Show the Wiring Does Not Help

Researchers wire the full fruit fly connectome (166,700 nodes) into a frozen LiquidAI LFM2.5-1.2B LLM, but controls show no fly-specific benefit.

The Fly Language Model (FLM) couples the complete MaleCNS v1.0 fruit fly connectome (166,700 nodes, 25,582,938 edges) to a frozen LiquidAI LFM2.5-1.2B-Instruct backbone, training only a 278,528-parameter readout (~0.0238% of backbone parameters). The fly readout improved NLL by 0.0222 nats/token (perplexity 3.98 to 3.90) on 32 SmolTalk dialogues, but a direct-input control without the graph beat it in all three seeds. Relabeling node identities removes the gain and the recurrence contracts state differences by 0.6 per token, so the connectome adds no long-range memory. The MIT-licensed code runs locally on Python 3.12, but study artifacts remain private, limiting independent reproducibility.

MarkTechPost · 4d agoAI research1

NVIDIA Details BioNeMo Inference Runtime (BioIR): 2.90x Higher Boltz-2 Folding Throughput and 58.5K Residues per GPU-Hour on 8xH100

NVIDIA released BioNeMo Inference Runtime (BioIR), an open-source PyTorch-compatible library delivering 2.90x higher Boltz-2 protein-folding throughput on 8xH100 GPUs.

NVIDIA detailed BioIR, a Python library that accelerates Boltz-2, OpenFold2, and OpenFold3 structure-prediction inference on NVIDIA GPUs while preserving standard PyTorch workflows. On a matched benchmark of 1,000 human dimers on 8xH100 80GB GPUs, BioIR delivered 58.5K folded residues per GPU-hour versus 20.2K for a torch.compile baseline, a 2.90x throughput gain. BioIR already powered the AlphaFold Database expansion, generating about 31 million candidate complexes across 4,777 proteomes, with 1.81 million released as high-confidence predictions. Extrapolated to 1 million targets, estimated folding energy drops from 35 MWh to 11 MWh at 8-GPU TDP equivalents.

MarkTechPost · 5d agoAI tools & infra1

Not just Korea: Google leaked identifying info for sex crime victims across the world

Google exposed identifying information of sex crime victims who filed image-removal requests worldwide, not only in Korea, the Hankyoreh confirmed.

The Hankyoreh, reporting by Shin Da-eun and Park Kang-su, confirmed that Korea was not the only country where victims who sent Google removal requests about illegally obtained sexual images had their private information exposed online. The leak affected victims across the world, compounding harm to a highly vulnerable population. One quoted victim described photos taken when they were a minor being distributed without consent.

DataBreaches.net · 3d agoData breach

How Far Can Synthetic Data Take Thai OCR?

Synthetic-only training adapts PaddleOCR-VL into Wayu-Paxa-OCR-Zero, cutting Thai printed-page CER from 6.64% to 1.24% without real labels.

The study disentangles which factors of synthetic OCR data transfer to real Thai documents, finding typeface diversity, 2D structure, and real handwriting glyphs matter most. Using 45,723 synthetic pages, the authors adapt the 0.9B-parameter PaddleOCR-VL-1.6 into Wayu-Paxa-OCR-Zero, reducing median CER from 6.64% to 1.24% on printed pages and from 74.87% to 20.55% on handwriting. The model outperforms Typhoon OCR v1 7B on all five evaluation sets.

Hugging Face daily papers · 14d agoAI research

Apple Reference Image: A New Approach for Verified Photography

Apple introduces Reference Image, hardware-backed verifiable photography on iPhone 18 Pro using sensor signing and Private Cloud Compute to counter AI-generated fakes.

Apple announced Reference Image, an opt-in camera mode debuting on the main sensor of iPhone 18 Pro and iPhone 18 Pro Max that produces securely timestamped, verifiable photographs. The design splits into two phases: a secure digital negative created by cryptographically signing pixel data at the sensor immediately after capture (preventing injection or tampering), then developing that negative into a reference image. Private Cloud Compute handles processing without exposing image contents to anyone, including Apple, and fraudulent reference images can be revoked without revealing the photographer's identity. Apple positions the system as stronger than C2PA-based approaches, which sign metadata after capture, are vulnerable to editing-chain compromise, and can tie images to a device or individual.

Hacker News · security · 18h agoResearchHN 25↑ · 18 comments

How Does mHC Use Its Residual Streams? Selective Routing and Near-Identity Mixing

Analysis of DeepSeek-V4-Flash shows four-stream mHC residual blocks use only about two streams effectively, with late-layer mixing providing little benefit.

The study examines the four-stream residual pathway of DeepSeek-V4-Flash, finding typical attention or FFN sites effectively use about two streams and that residual mixing is modest, occurring primarily in early layers. Replacing late mixers with identity increases C4 perplexity by only 1.9% while replacing early mixers raises it by 41%. Retaining the three largest routing weights per token increases perplexity by at most 2.7%, showing the model uses only part of the flexibility afforded by the four-stream design.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research

MantaxOtax Android Malware Combines Ransomware With Spyware

Zimperium analyzed MantaxOtax Android malware combining AES file encryption with extensive spying, linked to Indonesian actors and distributed via sideloading.

Zimperium's zLabs published a technical analysis of MantaxOtax, an Android malware family that combines ransomware-style file encryption with comprehensive spyware, linked to Indonesian threat actors and distributed via sideloaded APKs on a third-party file-sharing service. The malware requests device administrator, SMS, contacts, storage and Accessibility permissions, resolves its C2 domain dynamically from a GitHub repository, and encrypts files with AES using per-device keys derived from the Android ID on Android 9 and earlier. It steals WhatsApp messages, Telegram credentials, OTPs and other data, and uses MediaProjection for screenshots and screen recording staged on Catbox; a second variant adds WebSocket C2 with persistent screen locking and app blocking.

Infosecurity Magazine · 6d agoMalware

WarmBloodAban/Minimax-h3_Singularity — new model trending #22 on Hugging Face

Community fine-tune Minimax-h3_Singularity enhances MiniMax-H3 video generation with HDR quality, distant face restoration, and improved motion, trending #22 on Hugging Face.

Minimax-h3_Singularity is a community fusion fine-tune of the MiniMax-H3 multimodal video generation model, built from multiple checkpoints and refined with pruning and weight optimization. It supports Text-to-Video, Image-to-Video, Reference-to-Video, and Video-to-Video workflows in ComfyUI, and claims improvements in HDR clarity, distant face restoration, motion fluidity, and fantasy VFX. The authors recommend pairing it with the minimax_h3_ref2v_turbo_4step_v0.1 LoRA for four-step accelerated inference, and an online demo is available via RunningHub.

Hugging Face trending models · 11d agoModel release7· 1 read

[AINews] DeepSeek v4.1-Flash: 763B-P8B-D16B novel causal Encoder–Decoder architecture with vision marks the Return of the Whale

DeepSeek released V4.1-Flash, an open-weight 763B-parameter model with a novel causal encoder-decoder architecture, 1M context, vision input, and MIT license.

DeepSeek launched V4.1-Flash, an open-weight MIT-licensed model using a novel causal encoder-decoder architecture with 763B total parameters and asymmetric active parameters: 8B for prefill and 16B for decode. It supports 1M-token context and text+image input, priced at $0.30 per 1M input and $1.20 per 1M output tokens with a 50% off-peak discount. Artificial Analysis scored it 40 on its Intelligence Index, above DeepSeek V4 Pro 0813, and Vals ranked it the #1 open-weight model ahead of Kimi K3. Baseten shipped day-0 support and Ollama began rolling it out to paid subscribers.

Latent Space · 4d agoModel release 4 sources1

Lightweight Vision Transformer Compression for On-Device Plant Disease Detection in Resource-Constrained Agricultural Field Conditions

A unified ViT compression pipeline (H-BAC pruning, quantization, distillation) cuts plant-disease models 54.5x to 6.01 MB while keeping 95.13% accuracy.

Researchers combined Hessian-Balanced Adaptive Block Pruning (H-BAC), guided by second-order sensitivity estimation, with quantization and attention-based knowledge distillation to compress Vision Transformers for on-device chilli plant disease detection in India. On a 3-class cross-village, cross-device out-of-distribution dataset, the integrated pipeline reduced model size from 327.42 MB to 6.01 MB (54.5x) at 95.13 +/- 2.32% accuracy, matching the 95.13% FP32 baseline. Ablations also show a directly trained 6.01 MB INT8 student reaches 94.87% accuracy, indicating where pruning and distillation add limited value.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research