Search: “isaac-lab”

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Discovery Foundation Models: Toward Open-Ended Discovery Intelligence

Paper defines Discovery Foundation Models with seven coupled capabilities for open-ended discovery, demonstrated via Zetema and GALILEO systems.

The paper formulates Discovery Foundation Models (DFMs) as general-purpose model systems for open-ended discovery, supporting seven coupled capabilities spanning problem discovery, formulation, representation construction, hypothesis formation, intervention, evidence-grounded revision, and continual improvement. It instantiates the framework with Zetema, which couples explicit research-state dynamics, verification and experimental gating, and cross-task Discovery Skill evolution. The framework is grounded with GALILEO, a real therapeutic-discovery system combining dry-lab reasoning with robotic wet-lab experimentation in a closed physical discovery loop; code is released on GitHub.

Hugging Face daily papers·updated Sep 14, 17:56 UTC · 2d ago·first Sep 13, 20:00 UTC · 3d agoAI research 2 sources

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Anthropic Says Seven China-Based AI Labs Ran Industrial-Scale Claude Distillation Attacks

Anthropic disrupted industrial-scale unauthorized Claude distillation by seven China-based AI labs, including Alibaba, DeepSeek, Moonshot, and Z.ai.

Anthropic identified and disrupted six illicit distillation campaigns since February 2026 run by seven China-based labs: Alibaba, Moonshot, DeepSeek, Z.ai (Zhipu), MiniMax, Xiaomi, and SenseTime. The largest, GTG-16005, involved 151 million exchanges targeting Claude Opus 4.6/4.7 chain-of-thought transcripts, peaking at roughly 3 million exchanges per day from more than 3,500 fraudulent accounts. Labs used proxy/relay services with fictitious identities, fake or stolen credit cards, harvested API keys, and purchased conversation transcripts from third-party resellers. Anthropic is countering by banning reseller accounts, summarizing internal reasoning before responding, and introducing preserved thinking in Fable 5.1, which encrypts reasoning and prevents context edits before it.

The Hacker News·Sep 11, 16:15 UTC · 5d agoAI safety & security 9 sources

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How a researcher uses Codex and ChatGPT to search for new antimicrobial molecules

OpenAI profiles César de la Fuente's lab using ChatGPT and Codex alongside deep-learning models to accelerate antimicrobial molecule discovery.

OpenAI published a case study on bioengineer César de la Fuente's lab, which uses ChatGPT and Codex for hypothesis brainstorming, code writing, dataset processing, and bridging knowledge gaps across biology, chemistry, and computer science. The lab's deep-learning models scan genome and protein databases for antimicrobial peptide candidates, potentially cutting initial searches from years to hours. Bacterial antimicrobial resistance was associated with about five million deaths in 2021, a toll projected to roughly double by 2050.

OpenAI News·Sep 10, 16:00 UTC · 6d agoAI industry1

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Intezer adds native response automation without separate SOAR

Intezer launched Workflows, native response automation inside its AI SOC, letting teams automate remediation without a separate SOAR platform.

Intezer announced Workflows, a native automation and response builder inside its AI SOC platform that lets security teams run post-investigation actions such as closing alerts, isolating hosts, and updating tickets without a separate SOAR. Workflows are created through natural language via MCP, inherit full investigation context, and are logged for audit, with per-tenant routing and customer communications aimed at MSSPs. The announcement cites Intezer's AI SOC Report 2026 finding that nearly 1% of real incidents trace back to lowest-severity alerts.

Help Net Security·Aug 19, 00:00 UTC · 29d agoTools

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Testing race conditions with memory access tracing and stack-based delay injection

Google Project Zero released MAccConc, Linux kernel tooling that traces memory accesses to explore and test race condition interleavings.

A Google Project Zero researcher published MAccConc (Memory Access Concurrency), tooling for exploring possible interleavings of multithreaded test cases in the Linux kernel, available on GitHub. The tools use KCOV with ASAN outline-mode instrumentation to record per-access memory traces, enabling automatic testing of all A-B-A interleavings plus terminal and GUI explorers for manual analysis. The work targets confirming race condition candidates, building reliable regression tests, and enabling concurrency fuzzing, drawing on ideas from SKI and Ned Williamson's sockfuzzer.

Google Project Zero·Sep 8, 07:00 UTC · 8d agoResearch1

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NVIDIA Details BioNeMo Inference Runtime (BioIR): 2.90x Higher Boltz-2 Folding Throughput and 58.5K Residues per GPU-Hour on 8xH100

NVIDIA released BioNeMo Inference Runtime (BioIR), an open-source PyTorch-compatible library delivering 2.90x higher Boltz-2 protein-folding throughput on 8xH100 GPUs.

NVIDIA detailed BioIR, a Python library that accelerates Boltz-2, OpenFold2, and OpenFold3 structure-prediction inference on NVIDIA GPUs while preserving standard PyTorch workflows. On a matched benchmark of 1,000 human dimers on 8xH100 80GB GPUs, BioIR delivered 58.5K folded residues per GPU-hour versus 20.2K for a torch.compile baseline, a 2.90x throughput gain. BioIR already powered the AlphaFold Database expansion, generating about 31 million candidate complexes across 4,777 proteomes, with 1.81 million released as high-confidence predictions. Extrapolated to 1 million targets, estimated folding energy drops from 35 MWh to 11 MWh at 8-GPU TDP equivalents.

MarkTechPost·Sep 10, 21:57 UTC · 6d agoAI tools & infra1

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Y Combinator’s Garry Tan wants U.S. open-weight AI labs to ‘distill’ frontier models, too

Y Combinator CEO Garry Tan urges US open-weight labs to distill frontier models and regulators to stay out, countering Anthropic's crackdown calls.

Y Combinator CEO Garry Tan told CNBC he would "do nothing" about Chinese labs distilling frontier models and floated an "American distillation regime" letting US open-weight labs do the same to American frontier labs. Anthropic this week released its second report alleging Chinese labs conduct "illicit distillation attacks" using hidden identities, fraud, and stolen credentials, and CEO Dario Amodei has called for US regulators to crack down. Tan argued closed labs cannot dictate what customers do with API outputs, noting frontier labs trained on copyrighted material without permission, and called a single monolithic proprietary provider the true AI doomer scenario.

TechCrunch · AI·Sep 11, 20:59 UTC · 5d agoAI industry

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Israel Is Running a Synthetic Think Tank to Influence AI Search Results

Israel funds the Hanover Institute, an AI-generated think tank by ad firm Piro, publishing 100+ articles to influence LLM chatbot answers about Israel.

The Hanover Institute for Public Policy, run by American ad firm Piro Inc and paid for by Israel through HAVAS Media and the state ad agency LaPam, has published more than 100 articles in under a month. The AI detection tool Pangram found tested articles entirely AI-written except their bibliographies, and the site includes an llms.txt file to make it easier for LLMs to scrape. FARA filings show a $900,000 project invoice plus a $100,000 payment, and Piro advertises an 'AI Story Optimization' service for shaping chatbot answers.

404 Media·Aug 25, 18:35 UTC · 22d agoAI safety & security

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Former OpenAI researcher builds an AI model that judges options instead of writing text

TypeSafe AI launches Jev, a judgment-only model built by ex-OpenAI staff that classifies inputs with 70-500 ms latency instead of generating text.

Startup TypeSafe AI, co-founded by former OpenAI researcher and InstructGPT co-author Diogo Almeida, introduced Jev, a model that scores developer-defined answer options with probabilities rather than generating free-form text. The company claims 70-500 ms responses, parallel multi-question evaluation, and $0.042 per million input tokens with free outputs, targeting request routing, sales intent scoring, and assistant guardrail checks. Benchmarks are self-built and not independently verified, the 'no hallucination' guarantee only covers output structure, and access is currently via waitlist.

The Decoder·Sep 16, 15:19 UTC · 9h agoAI industry

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Pegasus Zero-Click Exploit Infects Serbian Student Activist's iPhone

Citizen Lab and SHARE Foundation confirm a Serbian student activist's iPhone was infected with NSO Group Pegasus via a zero-click iMessage exploit.

Forensic analysis found high-confidence infection indicators on the activist's iPhone during December 2025 and January 2026, using an iMessage zero-click exploit the Citizen Lab believes was patched as of iOS 18.4.1, released April 2025. The target was among at least 14 Apple Threat Notification recipients in Serbia's student movement, civil society, and opposition politics documented by the SHARE Foundation. Targeting occurred ahead of key 2026 election cycles; Amnesty Tech also confirmed a new NoviSpy version on another student movement member's device.

Infosecurity Magazine·Sep 3, 15:25 UTC · 13d agoThreat actor in the wild

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AI Is Learning to Write Genetic Code

AI models generated viable bacteriophage genomes, with 16 designs successfully replicating and some outperforming the original virus at attacking E. coli.

Two AI models generated complete genome designs for bacteriophages modeled on ΦX174, a virus known to infect E. coli. Researchers produced about 700,000 candidate designs, selected 285 promising ones, and synthesized DNA inserted into E. coli, yielding 16 viable viruses. Some of the newly generated viruses proved more effective at attacking E. coli than the original bacteriophage.

Schneier on Security·Aug 21, 16:52 UTC · 26d agoAI research

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AI-designed drug appears to turn back the body's biological clock in early trial

Insilico Medicine's AI-designed drug rentosertib showed reduced predicted biological age in IPF trial blood analysis, published in Nature Biotechnology.

Insilico Medicine reported that rentosertib, an AI-designed drug candidate in Phase III trials for idiopathic pulmonary fibrosis, showed reduced predicted biological age in blood protein analysis of 42 trial patients. Six independent aging-clock models built by teams at Harvard, Oxford, Beijing, and Insilico all predicted lower biological age versus placebo, with drops of three to four years by week 4 and up to six years on one clock. The drug targets TNIK and was developed with two generative AI systems in about 18 months; Eli Lilly recently invested in the company. Experts including Eric Topol and Harvard's Vadim Gladyshev called the results encouraging but not definitive, citing small sample size.

The Decoder·Sep 7, 16:34 UTC · 9d agoAI industry

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How XPUs Meet a World-Class AI Factory

NVIDIA argues AI factories with custom XPUs and NVLink Fusion connectivity must optimize tokens-per-second, tokens-per-watt, cost and uptime.

NVIDIA published a blog explaining that AI factories running continuously are economically defined by delivered output: tokens per second, tokens per watt, cost per token, utilization and uptime. It argues hyperscalers and AI-native companies building custom XPUs need infrastructure designed as a complete factory rather than collections of individual accelerators. The piece promotes NVIDIA's NVLink Fusion and full-stack XPU connectivity as the foundation for such world-class AI factory builds.

NVIDIA Blog·Aug 24, 15:00 UTC · 23d agoAI industry

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Dr. Claw: An AI Scientist Workspace for Vibe Research

Researchers release Dr. Claw, an open-source auditable workspace that wraps coding agents like Claude Code for end-to-end AI-assisted research workflows.

Paper 2609.00365 presents Dr. Claw, an open-source workspace that wraps existing coding-agent executors such as Claude Code and Gemini CLI in a controllable, human-in-the-loop research workflow. It uses persistent state objects, a reusable skill library, and multi-executor coordination to make research decisions auditable and recoverable, rather than adding another autonomous agent. Holding the executor fixed, Dr. Claw scores higher on research completeness than a bare command-line agent while preserving an auditable process trail. The code is released under AGPL-3.0 on GitHub (OpenLAIR/dr-claw).

Hugging Face daily papers·Aug 30, 20:00 UTC · 17d agoAI research1

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BugBase Pentest Copilot Enterprise automates black-box pentesting

BugBase launched Pentest Copilot Enterprise, an autonomous AI black-box pentesting platform using parallel agents to attack 100 vulnerability classes with validated PoCs.

BugBase announced Pentest Copilot Enterprise, which performs black-box red teaming without source-code access while maintaining authenticated context. Parallel specialized agents map pages, APIs, accounts and business functions, then execute iterative attacks across 100 vulnerability types including authentication, injection and business-logic flaws. The tool uses real Chromium browsers to preserve cookies, tokens, CSRF state and multiple identities, and navigates WAFs, bot detection, CAPTCHA and T-OTP. BugBase claims full scope coverage on OWASP Juice Shop, Broken Crystals and GOAD, NHA, and DRACARYS Active Directory labs.

Help Net Security·Sep 4, 12:28 UTC · 12d agoTools

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Evaluating Verified Autonomy in Quantum Engineering

Quantum-Harbor lab and QIQCBench (49 tasks) expose wide performance gaps across 17 frontier agentic systems in verified quantum engineering.

Researchers built Quantum-Harbor, a virtual laboratory providing a controlled execution environment where scientific AI agents interacting with quantum systems can have both actions and conclusions directly verified. QIQCBench contributes 49 expert-authored tasks spanning calibration and control, error correction and compilation, and sensing and networking. Across 17 frontier agentic systems, verified performance varied widely, exposing a substantial gap between demonstrated capability and reliable autonomous operation.

arXiv cs.AI / cs.LG / cs.CL·Sep 15, 16:46 UTC · 1d agoAI research1

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Re: Retrospective by 'gpg.fail' authors

GPG exploitation talk author clarifies a format-string 0day enabling code execution via printf %n writes and a polyglot PEM certificate payload.

Lexi Groves, author of the gpg.fail talk, clarified on oss-security that the first finding was an actual zero-day: a classic printf injection using %n for memory writes, with multiple X.509 certificates in one PEM file to re-enter and defeat ASLR before calling execv@plt. The payload executed the certificate itself, a polyglot file made by inserting a shebang and bash command into the PEM. A second finding was hash-collided by another party before the author could exploit it.

oss-security·updated Sep 16, 17:16 UTC · 7h ago·first Sep 16, 00:50 UTC · 1d agoResearch 8 sources

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Biology-in-the-loop: Amortized Adaptive Hit Discovery in CRISPR Screens

Researchers release AssayBench-Loop, a 1,389-screen CRISPR benchmark, and AssayLoop, a framework that learns adaptive hit discovery policies.

The paper introduces AssayBench-Loop, a large-scale benchmark of 1,389 CRISPR screens across five phenotype categories for adaptive hit discovery under budget constraints. It also introduces AssayLoop, which combines AssayFormer, a transformer-based amortized acquisition policy trained across historical screens, with LLM-derived biological priors via an adaptive handoff. On temporally held-out screens, AssayLoop achieves 5.67-fold enrichment over random selection and recovers 27.7% of hits after assaying roughly 5% of the candidate library, outperforming existing adaptive-design methods and standalone LLMs.

arXiv cs.AI / cs.LG / cs.CL·Sep 10, 17:45 UTC · 6d agoAI research1

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How GPT-5.6 Sol helps run quantum computing experiments

OpenAI describes an MIT researcher using GPT-5.6 Sol with Codex to autonomously run and calibrate quantum computing experiments.

OpenAI published a case study showing how an MIT researcher uses GPT-5.6 Sol together with Codex to autonomously run quantum computing experiments, analyze results, and calibrate qubits. The post is a product application story rather than a new benchmark, paper, or model release.

OpenAI News·Sep 8, 17:00 UTC · 8d agoAI industry1

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NVIDIA Open-Sources OSMO: One YAML Orchestrates Physical AI Training, Simulation, and Robot Testing

NVIDIA open-sourced OSMO, a Kubernetes-native YAML orchestrator running physical-AI training, simulation, and robot testing across mixed GPU tiers.

OSMO (Apache-2.0, latest release 6.3.1) lets teams describe training, simulation, and hardware-in-the-loop pipelines in a single YAML and routes tasks across datacenter GPUs (GB200), workstation RTX hardware, and edge devices like Jetson AGX Thor. It ships Helm charts and containers on NGC, uses the KAI Scheduler with NVLink topology-aware placement, and includes RBAC, OAuth2, and TLS termination. NVIDIA says it is battle-tested on GR00T, Isaac Lab, Isaac Sim, and Isaac ROS, and integrates with Claude Code, OpenAI Codex, and Cursor agents.

MarkTechPost·Sep 14, 08:04 UTC · 2d agoAI tools & infra

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An Open Recipe for IMO Gold: Training Nemotron for Olympiad Mathematics

Open post-training pipeline turns Nemotron 3 Ultra checkpoints into an IMO 2026 gold-medal system, scoring 30/42 without formal provers or external tools.

Starting from Nemotron 3 Ultra, researchers trained two specialist checkpoints using supervised fine-tuning and reinforcement learning for natural-language olympiad proof generation. Three checkpoints power an iterative generate-verify-refine search plus a separate high-compute selection stage, operating entirely in natural language with no formal prover, external tools, or internet access. The system scored 30 of 42 points at IMO 2026, reaching the gold-medal threshold. The release includes the post-trained checkpoints, training data, training and inference code, submitted solutions, and Nemotron-IMO-Bench with 200 novel olympiad-level problems.

Hugging Face daily papers·Sep 8, 20:00 UTC · 8d agoModel release

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AI research startup Listen Labs scrubbed a $1.5B funding round for Salesforce talks

Listen Labs abandoned a signed $125M Series C term sheet at a $1.5B valuation amid acquisition talks with Salesforce at roughly $2 billion.

Listen Labs, a three-year-old voice AI market research startup with about $30 million in annualized revenue, signed a term sheet for a $125 million Series C led by Menlo Ventures at a $1.5 billion valuation but walked away before closing. The financing likely collapsed due to acquisition talks with Salesforce at around $2 billion, though no deal is finalized. Competitor Simile recently closed a $200 million Series B at a $2 billion valuation, resetting benchmarks for the sector. Listen Labs' customers include Microsoft, Canva, Anthropic, and Sweetgreen.

TechCrunch · AI·Sep 10, 00:00 UTC · 7d agoAI industry

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Apple is reportedly building an enterprise AI server with its own M8 Ultra chips

Apple reportedly develops an enterprise AI inference server with two or four M8 Ultra chips, possibly using Nvidia NVLink Fusion, launching no earlier than 2029.

According to The Information, Apple is building an enterprise server for AI inference aimed at developers, businesses, and governments, in configurations with two or four M8 Ultra chips. Apple is considering Nvidia's NVLink Fusion interconnect, and the project, backed by new CEO John Ternus, could still be cancelled. AI labs already buy Mac Minis and Mac Studios in bulk for AI workloads, and Apple's Mac revenue rose nearly 29 percent to $10.4 billion last quarter.

The Decoder·updated Sep 16, 22:02 UTC · 2h ago·first Sep 16, 18:16 UTC · 6h agoAI industry 3 sources

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AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

Google DeepMind released AlphaGenome Atlas, a free 1-petabyte platform predicting the molecular effects of all ~9 billion possible single-letter DNA variants.

Google DeepMind introduced AlphaGenome Atlas, containing precomputed predictions for the effects of roughly 9 billion single-nucleotide variants across the human genome, spanning hundreds of human and mouse cell types. The 1-petabyte dataset is more than 30 times larger than the AlphaFold Database and includes an AlphaGenome Variant Impact (AVI) score combining AlphaGenome and AlphaMissense predictions for both coding and non-coding regions. External collaborators have already used it to identify and experimentally verify variants in unsolved rare disease research. It is available via a free web portal, the AlphaGenome API, and as a skill in Google Antigravity.

Google DeepMind·Sep 8, 14:00 UTC · 8d agoAI research 2 sources

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Stanford Researchers Release Paper2Agent: Turning Research Papers Into AI Agents That Reproduce Results and Run on New Data

Stanford researchers released Paper2Agent, a Nature-published pipeline that turns research papers into MCP servers agents can execute.

A Stanford team led by Jiacheng Miao and James Zou published Paper2Agent in Nature on 16 September 2026. Built on Claude Code's agent SDK, it converts a paper and its codebase into a Model Context Protocol server with validated tools, resources, and prompts. In benchmarks, the AlphaGenome agent built 22 tools in about 45 minutes for US$14, scored 100% on 15 novel queries versus 78.7% for Claude Code with repository access, and cut median runtime 1.9x. In scale tests, 74 of 100 bioRxiv papers were converted and 593 of 599 proposed tools passed validation.

MarkTechPost·Sep 16, 21:59 UTC · 2h agoAI research

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Product showcase: AI Paper Trail shows the privacy cost of talking to AI

Proton launched AI Paper Trail, a free tool that analyzes ChatGPT or Claude exports and reports what personal data can be inferred from AI conversations.

Proton released AI Paper Trail, a free web tool that analyzes the 200 most recent prompts from exported ChatGPT or Claude conversation histories and generates a privacy report with an AI Exposure Score, inferred personal data categories, and an estimated advertising value. In a hands-on test it identified 47 data points, returned a 58/100 exposure score, estimated $185 in advertising value, and flagged five red flags spanning location, interests, finances, and relationships. Proton states that uploaded data is deleted after analysis and is not stored on its Lumo servers.

Help Net Security·Aug 24, 00:00 UTC · 24d agoAI industry

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Early Anthropic hire, former METR COO have found a way to rein in rogue AI agents

Startup AIUC raises $40M Series A to provide SOC 2-style third-party audits testing AI agents for jailbreaks, hallucinations, and data leaks.

Artificial Intelligence Underwriting Company (AIUC), founded by early Anthropic employee Rune Kvist and former METR COO Rajiv Dattani, announced a $40 million Series A led by Ribbit Capital, bringing total funding to $55 million. Its AIUC-1 standard and testing service runs AI agents through roughly 5,000 tests covering jailbreaks, hallucinations, and data leaks, producing a roughly 100-page audit report verified by humans. Customers include Cursor, Lovable, Harvey, and ElevenLabs.

TechCrunch · AI·Sep 15, 13:00 UTC · 1d agoAI safety & security

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Quoting Calif Research

Calif Research demos WeWorm, an AI-built zero-click worm that spreads via WeChat calls on iOS and Android without user interaction.

Calif Research released a demo of WeWorm, described as the first zero-click worm to spread through WeChat calls across iOS and Android; victims need not answer the call and hear nothing even if they do. The team used AI to find the underlying bug and write a remote code execution exploit in about two days, then spent one more week building the worm. The researchers argue AI can now do most of the exploit-development work, with humans supplying judgment on targeting and safe testing.

Simon Willison·Sep 10, 00:56 UTC · 6d agoAI safety & security

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Nous Research Adds One-Click Local Model Setup to Hermes Desktop

Nous Research's Hermes Desktop now offers one-click local model setup that reads hardware, picks a fitting quantization, downloads weights, and configures llama.cpp automatically.

Hermes Desktop, the MIT-licensed build of the open-source Hermes Agent, now sets up local models in one click: it reads the machine's hardware, selects a model that fits, downloads weights, and configures the inference runtime. It manages a pinned llama.cpp build with CUDA, Metal, Vulkan, HIP, and CPU backends, and shows green/amber/red memory-fit verdicts per catalog model before download. Quantization floors at 4-bit, and recommended models guarantee at least a 64K context window protected by ordered RAM offload (expert weights first, never the attention cache). It runs on macOS 12+, Windows 10/11, and Linux with no account required for local models.

MarkTechPost·Sep 5, 19:12 UTC · 11d agoAI tools & infra1

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