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Threat Assessment: Ryuk Ransomware

Unit 42 assesses Ryuk ransomware amid a CISA/FBI/HHS alert on threats to U.S. healthcare, including the UHS attack that disrupted hospital operations.

A joint CISA, FBI, and HHS alert on October 28, 2020 warned of an imminent threat to U.S. healthcare from operators deploying Trickbot and Ryuk ransomware. Universal Health Services reported a Ryuk attack that disrupted all U.S. UHS sites for weeks, with similar incidents at hospitals in Oregon and New York. Ryuk typically arrives after Trickbot or BazaLoader infections delivered via malicious email, and operators enumerate networks with PowerShell and WMI before encryption. The Trickbot Anchor_DNS module performs DNS tunneling for C2, using connectivity checks to benign domains like ipinfo.io and checkip.amazonaws.com.

Palo Alto Unit 42 · Aug 17, 2026Ransomware in the wild

ANY.RUN & SentinelOne: One Workspace, Instant Context for Rapid Response

ANY.RUN integrates its interactive sandbox, IOC lookups, and STIX/TAXII threat feeds natively into SentinelOne for faster automated malware triage.

ANY.RUN and SentinelOne launched connectors that embed interactive sandbox analysis and threat intelligence into the SentinelOne console via Singularity Hyperautomation. Suspicious files and URLs from alerts are automatically submitted to the ANY.RUN sandbox, with behavioral verdicts and risk scores returned into alert notes. On-demand IOC lookups draw on sandbox history from 16,000 organizations and 700,000 analysts. A separate STIX/TAXII feed streams verified malicious IPs, domains, and URLs through the SentinelOne Marketplace TAXII Connect app.

ANY.RUN · 10h agoTools