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Discovery Foundation Models: Toward Open-Ended Discovery Intelligence
Proposes Discovery Foundation Models that participate in creating new problems and knowledge, instantiated in Zetema and the GALILEO therapeutic-discovery system.
The paper formulates Discovery Foundation Models (DFMs) as general-purpose systems for open-ended discovery, supporting seven coupled capabilities from problem discovery through evidence-grounded revision and continual improvement. It instantiates the framework with Zetema, combining explicit research-state dynamics, verification gating, external grounding, and cross-task Discovery Skill evolution. GALILEO, a real therapeutic-discovery system, closes the loop between Dry-Lab reasoning, robotic and hands-on Wet-Lab experimentation, and iterative hypothesis revision. The authors also define process-centered evaluation so discovery behavior can be trained and measured beyond final answers.
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Credentialed Pre-Port Discovery: Don't Probe the Host, Ask it
Rapid7's version 8.58 adds credentialed pre-port discovery, letting scan engines query hosts for listening TCP/UDP ports instead of network probing.
Rapid7 documents credentialed pre-port discovery, available from version 8.58 as an off-by-default per-template option under Asset Discovery. The scan engine authenticates with existing SSH, Scan Assistant, or Windows credentials and receives the host's authoritative list of listening TCP and UDP ports, skipping the network port scan. Hosts without matching credentials silently fall back to network port scanning. Trade-offs include reporting firewall-blocked ports the engine cannot reach, longer scans, and early termination findings caused by repeated connection failures.
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Introducing context-aware vulnerability discovery and remediation with Cloudflare Managed Defense and OpenAI Daybreak models
Cloudflare launches invitation-only Vulnerability Discovery and Remediation within Managed Defense, using OpenAI Daybreak models and WAF context to prioritize and patch vulnerabilities.
Cloudflare announced early access to Vulnerability Discovery and Remediation, an invitation-only service within Cloudflare Managed Defense. The service uses OpenAI Daybreak models, including GPT-5.6 Cyber, via the Daybreak Defense Network to hunt and validate vulnerabilities in customer-authorized codebases across Workers and proxied applications. Findings are prioritized using production traffic, WAF rule, and security event context, and proposed patches and WAF mitigations are automatically checked before customer review.
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Scores Alone Do Not Prove Discovery: The Discovery Certification Protocol for Auditing AI Research Agents
Researchers introduce the Discovery Certification Protocol, an auditable test framework that verifies whether AI research agents' claimed discoveries are genuine.
The Discovery Certification Protocol (DCP) converts AI research agents' discovery claims into executable recovery and feedback tests organized as gated audits. Controlled audits in SQLite optimization and virtual catalyst control produced zero recoveries in 96 episodes, with an upper bound of 0.0468. A deterministic, LLM-free verifier reproduces audit decisions from frozen evidence, giving AI research a common evidence language for outcomes, alternative routes, and feedback effects.
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Threat Brief: Maze Ransomware
Unit 42 issued a threat brief on Maze ransomware, noting an uptick across industries and exploitation of Pulse VPN and IE flaws for initial access.
Palo Alto Networks detected an uptick in Maze ransomware samples across finance, healthcare, government, and other sectors. Maze, a variant of ChaCha ransomware first seen in May 2019, is distributed via weaponized Word/Excel attachments and the Spelevo exploit kit leveraging CVE-2018-15982 and CVE-2018-4878, and has used CVE-2019-11510 (Pulse VPN) and CVE-2018-8174 (Internet Explorer). Operators establish a foothold, escalate privileges, move laterally, and exfiltrate files before encryption for extortion leverage.
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CausalArena: Benchmarking Causal Discovery in the Foundation Model Era
Researchers introduce CausalArena, a unified benchmark revealing that causal discovery rankings shift substantially across structural causal model families and protocols.
The paper presents CausalArena, a unified and evolvable benchmark for causal discovery combining synthetic structural causal models, semantically grounded operational SCMs, formula-grounded scientific SCMs, and public real-world datasets. Experiments across classical, neural, and pretrained causal discovery foundation models show large ranking shifts between benchmark regimes. The authors identify pretraining-evaluation overlap and benchmark diversity as central evaluation challenges.
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AI vulnerability discovery scores the highest impact of 20 emerging risks
Gartner survey of 316 organizations ranks AI-driven vulnerability discovery as the top emerging risk, with tangible impact expected within roughly two years.
Gartner's quarterly survey had 316 risk managers, auditors, and senior executives rank 20 emerging threats in April and May, with AI discovery of cyber vulnerabilities ranked first, up from outside the top five the prior quarter. Respondents scored the impact time frame at 1.92 on a scale where 1 means under a year and 2 means one to two years, and 76% placed it in their top ten, ranking first in all four regions and highest among banking and financial respondents at 78%. The analysis notes AI now finds unknown flaws at volumes patching teams cannot absorb and that exploit development time has collapsed, citing defensive efforts like Anthropic's Project Glasswing and OpenAI's Daybreak. Gartner recommends recalibrating cyber risk impact, revisiting risk appetite, demanding stronger vendor security validation, and moving toward faster automated remediation.
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Biology-in-the-loop: Amortized Adaptive Hit Discovery in CRISPR Screens
Researchers release AssayBench-Loop, a 1,389-screen CRISPR benchmark, and AssayLoop, a framework that learns adaptive hit discovery policies.
The paper introduces AssayBench-Loop, a large-scale benchmark of 1,389 CRISPR screens across five phenotype categories for adaptive hit discovery under budget constraints. It also introduces AssayLoop, which combines AssayFormer, a transformer-based amortized acquisition policy trained across historical screens, with LLM-derived biological priors via an adaptive handoff. On temporally held-out screens, AssayLoop achieves 5.67-fold enrichment over random selection and recovers 27.7% of hits after assaying roughly 5% of the candidate library, outperforming existing adaptive-design methods and standalone LLMs.
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Mythos Changed the Math on Vulnerability Discovery. Most Teams Aren't Ready for the Remediation Side
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