ZeroHour

Search: “NIH”

31 stories

Smart search ranks by meaning as well as keywords (one row per story, last 45 days).

Officials disrupt Chinese espionage operation that hit multiple federal agencies

FBI and DOJ seized QTFY infrastructure, disrupting a Chinese state-sponsored group that compromised federal agencies and critical infrastructure since 2018.

Authorities seized three domains powering QScan and QTRouter, the hacking suite of QTFY, a Chinese government-funded group operating through front company Nanjing Xinjiuwei Network Technology. Targets include the Departments of Energy, Justice, and Health and Human Services, the Federal Reserve, NASA, NIH, financial institutions, defense contractors, utilities, telecoms, and hospitals; the group exploited zero-days in Ivanti, Pulse Secure, Fortinet, Citrix, and others, intruding three DOE national labs in September 2024. QScan carried over 200 proof-of-concept exploits and processed more than two million scanning tasks in a single day in 2024.

CyberScoop · 21d agoThreat actor in the wild1

Molecular Déjà Vu: Digit-Level Retrieval of Published Values in Frontier Language Models

Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.

An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research1

Evaluating Time-Series Foundation Models and Multimodal Dietary Context for CGM Forecasting

Study finds zero-shot time-series foundation models underperform on CGM forecasting; fine-tuned Chronos-Bolt cuts RMSE up to 18.4% and dietary context adds signal.

The paper evaluates time-series foundation models for continuous glucose monitoring forecasting across eight public datasets covering Type 1 diabetes, Type 2 diabetes, and non-diabetes populations. Under a unified protocol, zero-shot foundation models did not consistently outperform baselines like Elastic Net and PatchTST, but lightweight fine-tuning did, with fine-tuned Chronos-Bolt reducing RMSE by 6.5%-18.4% in the T1D cohort and 8.6%-18.2% in the non-diabetes/T2D cohort. A residual-based fusion framework adding dietary context from CGMacros reduced overall RMSE by about 3% and postprandial RMSE by about 15% versus CGM-only baselines.

arXiv cs.AI / cs.LG / cs.CL · 6d agoAI research

Right Tool, Right Job: Native-Language Evaluation, Tokenizer Sensitivity, and Methodological Findings from a French-Only BabyLM

French BabyLM entry METRON-FR (125M GPT-2, 92.47M words) shows tokenizer artifacts dominate child-scale zero-shot evaluation; proposes standard diagnostics.

METRON-FR is a 125M-parameter GPT-2 pretrained on 92.47M French words, submitted to the BabyLM 2026 Strict track, scoring 85.97% on the native Quebec-French QFrBLiMP benchmark and 62.80% on the BabyLM-weighted leaderboard. A cross-lingual GLUE protocol combining French task-data translation with rank-16 LoRA shows relational tasks gain while world-knowledge tasks regress. Bilingual Lexicon Induction reaches p@1 of 68.84%, 18x above chance, and ablations show single-token zero-shot scoring is dominated by tokenizer and template artifacts at child scale.

arXiv cs.AI / cs.LG / cs.CL · 1d agoAI research

NCP-ArchPreview Technical Report: Moving towards Latent Space Language Models through Next Concept Prediction

An 8.9B-parameter latent-space language model using next-concept prediction matches OLMo-3-7B pretraining loss with only 51.3% of the training tokens.

NCP-ArchPreview augments next-token prediction with Next Concept Prediction over a product-quantized concept vocabulary built from hidden states, trained jointly end-to-end. The 8.9B model was trained on 5.73T tokens from the Dolma-3 dataset, the largest latent-space language model demonstration to date. It consumes 51.3% of the tokens to reach OLMo-3-7B's final pretraining loss and outperforms it by 2.45 points on the downstream macro-average, including a 5.99-point GSM8K gain. The learned latent space also enables lightweight domain adaptation via a 17M-parameter VQ module and improves speculative drafting accepted length by 4.17%.

Hugging Face daily papers · 8d agoAI research1

The 2026 PNPL Competition: Word Classification and Efficient Cross-Subject Generalisation in LibriBrain100

The 2026 PNPL competition releases LibriBrain100, a MEG speech dataset with 32 extra subjects, targeting word classification and cross-subject BCI generalization.

The 2025 PNPL competition on non-invasive speech decoding from MEG achieved F1-macro scores of 95.6% for speech detection and 73.6% for phoneme classification, built on LibriBrain's ~50 hours of single-subject data. The 2026 edition extends this with LibriBrain100, adding 32 subjects (~40 minutes each) plus ~80 hours of within-subject data. Two tracks target within-subject word classification at scale and cross-subject generalization with subject-specific fine-tuning shrinking from ~40 to ~20 to ~10 minutes, aiming at clinically feasible non-invasive BCIs for people with profound paralysis.

Hugging Face daily papers · 14d agoAI research

K-Bench: a clinically calibrated benchmark for evaluating large language models in high-risk mental health conversations

Clinician-calibrated K-Bench evaluates 125 LLM configurations on 200 high-risk mental health vignettes, exposing wide variation in suicide and violence risk handling.

K-Bench is a clinician-calibrated, protected benchmark evaluating 125 model configurations from 33 base models across 14 providers on 200 multi-turn vignettes covering suicide, self-harm, domestic violence, substance misuse and no-risk presentations. A frozen GPT-4o judge achieved 94.2% exact agreement with clinician consensus across 6,751 eligible comparisons from 151 clinician-rated transcripts. Leading models combined supportive conversation with combined-risk scores above 95, while risk exploration varied substantially among weaker configurations; therapeutic prompting helped weaker models and elevated reasoning produced no average improvement. A continuously updated public leaderboard is hosted at k-bench.ai with protected test materials.

Bag of Tricks or Bag of Myths? Reducing Modeling Complexity with Task Knowledge in Explainable Suicide Risk Assessment

Researchers audit 31 NLP techniques for clinician-annotated suicide risk prediction, finding only 5 of 31 comparisons yield reliable gains.

A study of 1,635 clinician-annotated social media posts ran roughly 300 controlled experiments across 7 methodological families, auditing techniques such as model scaling, synthetic data, ensembling, and threshold tuning under severe class imbalance. The proposed system reformulates risk factor prediction as entailment between posts and codebook definitions, using architecturally diverse ensembles with class-balanced training and deployment-consistent calibration. It scores 0.8203 for risk, 0.7953 for evidence, and 0.7045 macro-F1 for factors, ranking third among 53 teams.

arXiv cs.AI / cs.LG / cs.CL · 9d agoAI research

UniH^3: Unifying Hierarchical Homogeneity and Heterogeneity for All-in-One Medical Image Restoration

UniH3 unifies hierarchical homogeneity and heterogeneity modeling for all-in-one medical image restoration across modalities and degradation types.

UniH3 introduces a Hierarchical Homogeneity Memory module that distills shared anatomical priors from high-quality images, injected via a Homogeneity-Guided Attention mechanism. A Hierarchical Heterogeneity Balancer mitigates inter- and intra-task conflicts during multi-task optimization. It achieves state-of-the-art on MedIR-2D-500K and MedIR-3D-3D benchmarks for both all-in-one and single-task restoration, with code released on GitHub.

Hugging Face daily papers · 7d agoAI research

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

Researchers introduce NOAH, a time-aware generative transformer trained on 559 million MIMIC clinical events to forecast multimodal patient trajectories.

NOAH is a task-agnostic, time-aware generative transformer trained on over 559 million clinical events from 431,000 hospital visits by 299,000 patients across the MIMIC dataset family. It uses bidirectional time integration and a variational latent space to model the stochastic evolution of patient states, natively processing medical images, time-series signals, categorical events, and structured or unstructured clinical records. The model supports autoregressive forecasting with optional time control, zero-shot classification, and counterfactual intervention simulation, with strong probing performance across clinical outcomes, 15 ICD chapters, and 29 comorbidities.

Hugging Face daily papers · 9d agoAI research1

NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting

Researchers introduce NOAH, a generative time-aware transformer trained on 559 million MIMIC clinical events to model and forecast patient trajectories.

NOAH is a task-agnostic, time-aware generative transformer designed to represent and forecast the full multimodal patient journey across medical images, time-series signals, categorical events, and clinical text. It was trained on over 559 million clinical events from 431,000 hospital visits covering 299,000 patients in the MIMIC dataset family. The architecture combines bidirectional time integration with a variational latent space to capture continuous patient state evolution and clinical stochasticity. NOAH supports autoregressive forecasting with time control, zero-shot classification, and counterfactual intervention simulation, with evaluations on 15 ICD chapters, 29 comorbidities, and time-to-event prediction.

arXiv cs.AI / cs.LG / cs.CL · 8d agoAI research2

Convergent Emergence of In-Context Learning Across Modalities

Controlled experiments show few-shot in-context learning emerges across six modalities including language, genomes, images, and proteins, partially supporting a convergence hypothesis.

The paper tests the Convergent Emergence Hypothesis: that few-shot in-context learning, when it emerges, shares a common cross-modality difficulty profile. A controlled framework instantiated the same task suite across six modalities: language, genome, integer sequences, time series, images, and proteins. Paired-mapping ICL emerged in all six modalities, surpassed controlled baselines, and showed correlated per-task effects in five of them, providing partial support for the hypothesis.

Hugging Face daily papers · 5d agoAI research

DianShi-RxnDB: A Large-Scale, Fine-Grained Organic Reaction Data Platform Built via a Fully Automated Pipeline for Researchers and AI Agents

Researchers release DianShi-RxnDB, a database of roughly 24 million organic reaction instances extracted automatically from USPTO and EPO patents since 1976.

DianShi-RxnDB is built by a fully automated pipeline integrating patent text, images, and reaction schemes, yielding about 24 million reaction instances, of which 14.8 million (61.7%) pass automated qualification checks. Manual evaluation of 1,300 sampled instances showed 92.95% field-level accuracy, and comparisons with Pistachio found advantages in deduplicated record counts and granularity. The platform offers a web research workbench and a Model Context Protocol (MCP) service enabling AI agents to perform composable structured retrieval.

Hugging Face daily papers · 11d agoAI research

Funding grants for new research into AI and teen development

OpenAI launched a $5 million grant program funding independent research on generative AI's effects on teen development, well-being, and safety.

OpenAI opened applications for a $5 million grant program supporting independent research into how generative AI affects teen development, well-being, and safety. The program was announced via the OpenAI newsroom on 2026-09-08.

OpenAI News · 8d agoAI industry

Everything in Moderation: Per-Domain Coverage Optima and Alignment-Resistant Domain Gaps in Multi-Domain Mid-Training

Controlled mid-training experiments on Qwen3-8B-Base find each domain has a 10-40% coverage optimum and domain gaps survive alignment SFT.

Using Qwen3-8B-Base (with a 4B replication) across five semantically rule-disjoint KOR-Bench domains, the authors train 30 data allocations spanning the five-domain simplex at five seeds each. All five domains show interior optima in the moderate 10-40% coverage band, and domain gaps persist after a fixed-budget compensatory SFT pass, which raises 116/120 cells yet bridges 0/240 pairs at a 5% threshold. Zero coverage collapses mid-training-only accuracy, though a FineWeb-Edu-only control shows the collapse is partly generic drift. The results argue mid-training data composition requires principled design rather than reliance on later alignment.

arXiv cs.AI / cs.LG / cs.CL · 8d agoAI research1

Technical Manual for a Toolkit for Measuring Contextual Individuation in Transformer Language Models

An open methodology toolkit measures whether transformer language models contextualize fixed word forms across domains using bridge forms and layer-wise silhouette analysis.

The manual documents an open toolkit built around 'bridge forms' - identical written words recurring across two or more subject domains with a different sense in each - to test whether transformer language models individuate word occurrences by context beyond the embedding layer. It covers declarative specification of bridge forms, Wikipedia corpus acquisition, occurrence localization, layer-wise representation extraction, domain-pairwise silhouette measurement, and visualization, justifying each choice against failure modes such as sense contamination and subword-tokenization misalignment. It is a methodological and implementation reference and reports no empirical results.

arXiv cs.AI / cs.LG / cs.CL · 12d agoAI research

From Parameters to Answers: How LLMs Retrieve and Use Their Internal Knowledge

Interpretability study traces how Qwen, Llama, and Gemma route query information and internal knowledge across layers when answering questions.

Researchers used layerwise interventions on hidden states to separate query-routing signals from target knowledge in language models, testing Qwen, Llama, and Gemma on country-continent questions with varied answer types. A pair-conditioned request direction strengthens before interventions alter downstream knowledge, opening a causal window while answer-supporting content is still forming. Trajectories differ by model: Gemma shows a partially overlapping mid-layer routing profile, while Llama has no sustained routing-effect window under the same gates.

arXiv cs.AI / cs.LG / cs.CL · 6d agoAI research1

LongAgent: History-Guided Agentic Search for Longitudinal Outcome Prediction

LongAgent autonomously searches variable sets and temporal windows to predict longitudinal medical outcomes, beating the strongest non-agent baseline on synthetic data.

The paper proposes LongAgent, an agent-based method that searches over combinations of variable sets, temporal windows and aggregation functions for outcome prediction on heterogeneous medical longitudinal data. It uses a history memory of previous searches and numerical evidence to guide exploration. On synthetic data it achieves mean RMSE 1.7376, improving over the best non-agent baseline by 0.0151 (95% CI [0.0045, 0.0260]; p=0.0273), and performs comparably to the best baseline on a real clinical dataset.

arXiv cs.AI / cs.LG / cs.CL · 2d agoAI research

Google DeepMind Releases AlphaGenome Atlas With Precomputed Molecular Effect Predictions and AVI Scores for 9 Billion Human DNA Variants

Google DeepMind launched AlphaGenome Atlas, precomputing molecular effect predictions and AVI impact scores for ~9 billion human single-nucleotide variants in a 1-petabyte catalogue.

Google DeepMind released AlphaGenome Atlas, a 1-petabyte catalogue of precomputed molecular effect predictions for roughly 9 billion possible single-nucleotide variants in the human genome. It introduces the AlphaGenome Variant Impact (AVI) score, combining AlphaGenome regulatory predictions with AlphaMissense, plus per-variant feature attributions and over 2,500 recurrent DNA sequence motifs. DeepMind reports best-in-class AVI performance on variant pathogenicity and rare disease benchmarks. Early users at the Broad Institute, University of Exeter, and Stowers Institute demonstrated rare-disease variant reprioritization and 22% more non-coding associations across 54,000+ UK Biobank genomes.

MarkTechPost · 8d agoAI research2

ActReview: Rebuttal-Guided Training Data and Rubric Rewards for Actionable Peer Review Generation

ActReview post-trains Qwen3-8B-Base on 40K rebuttal-derived instances with rubric rewards to generate actionable, grounded peer-review feedback, plus a 1,000-instance benchmark.

The framework builds ActReview-40K from real OpenReview review-rebuttal threads, aligning reviewer weaknesses with author responses and grounding feedback in localized paper evidence. Qwen3-8B-Base is post-trained with multi-task supervised fine-tuning followed by GRPO using candidate-aware, weakness-specific rubric rewards. Experiments show improved actionability and grounding over prior specialized review-generation models, supported by ActReview-Bench, a human-curated 1,000-instance evaluation set. Human evaluation confirms better revision usefulness while noting a remaining gap in technical accuracy.

arXiv cs.AI / cs.LG / cs.CL · 8d agoAI research

OmniMed-FL: A Robust Multimodal Federated Learning Framework for Clinical Diagnosis

OmniMed-FL benchmarks multimodal federated learning for chest radiograph diagnosis across 3-20 clients, with FedProx leading under severe non-IID skew.

OmniMed-FL studies multimodal federated learning combining chest radiographs and clinical notes for five-class condition classification under HIPAA/GDDR-compliant decentralized training. It benchmarks eight fusion strategies, imputation rules, and federated baselines under Dirichlet non-IID partitioning across 3-20 hospital clients. With 5 clients and severe skew (alpha=0.1), FedProx scored 0.737 macro-F1 versus 0.662 for FedAvg and 0.297 for local-only training. Multimodal fusion beat unimodal inputs (0.956 vs 0.934 text, 0.664 images) on the synthetic corpus.

arXiv cs.AI / cs.LG / cs.CL · 7d agoAI research1

Target leakage, not model class, explains reported accuracy in survey-based cardiovascular screening: a leakage-tiered audit of glass-box and tabular foundation models

Audits of 10 classifiers on BRFSS show target leakage, not model class, drives the reported 0.89 AUROC in survey-based cardiovascular screening.

The study benchmarks ten model classes, including glass-box and tabular foundation models, for prevalent myocardial infarction on 442,067 respondents of the 2022 BRFSS across five feature tiers of decreasing leakage risk. Removing two post-diagnostic features costs every model 0.049-0.051 AUROC and collapses performance into a 0.0045-wide band, and the explainable boosting machine matches all alternatives within 0.005 while scoring roughly 104x faster than the strongest foundation model. Frozen models transport within 0.002 AUROC to 2023 data; the authors conclude evaluation practice and feature sets, not model capacity, are the binding constraint.

arXiv cs.AI / cs.LG / cs.CL · 6d agoAI research1

Knowing What Not to Answer: Selective Non-Compliance in Vision-Language Models

Researchers introduce KoNA, a benchmark exposing vision-language models' failures at selective non-compliance, plus fine-tuning that improves refusal and abstention accuracy.

KoNA is a benchmark for evaluating selective non-compliance in vision-language models across five categories: False Premise, Visual Inaccessibility, Universal Unknown, Task Feasibility and Safety. It tests both query-level and component-level non-compliance using paired single and compound queries, and evaluations across diverse VLMs show models often fail to refuse, correct or abstain appropriately, with failures worsening on compound queries. Fine-tuning VLMs on KoNA examples substantially improves non-compliance accuracy while largely maintaining performance on fully answerable tasks.

Hugging Face daily papers · 13d agoAI research1

Anatomical Grounding and Leakage-Aware Multimodal Contrastive Learning for Alzheimer's Disease Classification from Structural MRI

Study of label leakage and anatomical grounding in multimodal MRI models for Alzheimer's staging shows cognitive-score fusion accuracy of 87.3% is leakage-driven.

The authors train a ResNet18 slice-based encoder with a one-layer Transformer on 1,075 ADNI-1 T1 MRI scans, using FastSurfer segmentations and YOLOv8 localization (mAP_50 above 0.96) as anatomical reference. Grad-CAM shows the image-only classifier often attends to skull and background rather than disease-relevant structures. A CLIP-style image-tabular contrastive framework organized along a label-leakage spectrum yields 87.3% three-way accuracy with cognitive scores versus 73.0% with regional volumes, and cropping to the medial temporal lobe raises image-only accuracy from 58.7% to 65.1%. Results come from single runs on a small balanced test set with reported confidence intervals.

arXiv cs.AI / cs.LG / cs.CL · 2d agoAI research1

CoRA-NAS: Coarse Ranking and Anchor-Residual Refinement for Neural Architecture Search

CoRA-NAS combines zero-cost proxy ranking with low-cost learning-curve refinement, achieving the best worst-space Spearman correlation across NAS benchmarks.

The paper proposes CoRA-NAS, a two-stage neural architecture search framework pairing a static ranking prior (CoRA-Rank) with learning-curve refinement (CoRA-Refine) that extrapolates early validation curves for sampled anchors and propagates residual corrections with an ExtraTrees model at about 1% of full training cost. Across NAS-Bench-201, NAS-Bench-101, TransNAS-Bench-101, and NATS-SSS it achieves mean Spearman correlations of 0.946, 0.715, 0.786, and 0.894 respectively, with the best worst-space correlation of 0.715 among compared methods. On NAS-Bench-201/CIFAR-100 its selected architecture reaches 73.32% accuracy versus a 73.37% ground-truth best.

arXiv cs.AI / cs.LG / cs.CL · 6d agoAI research

ActReview: Rebuttal-Guided Training Data and Rubric Rewards for Actionable Peer Review Generation

ActReview post-trains Qwen3-8B-Base on OpenReview rebuttals to generate actionable peer-review feedback with grounded revision suggestions, benchmarked on 1,000 curated instances.

The paper defines Actionable Peer-review Generation as diagnostic claim generation plus revision suggestion generation and introduces ActReview, a rebuttal-guided post-training framework. From OpenReview review-rebuttal threads the authors build ActReview-40K, aligning reviewer weaknesses with author responses grounded in localized paper evidence, and post-train Qwen3-8B-Base with multi-task SFT followed by GRPO using weakness-specific rubric rewards. They also release ActReview-Bench, a human-curated 1,000-instance benchmark, on which ActReview outperforms prior specialized review-generation models on actionability and grounding while remaining competitive with strong prompt-based LLMs. Human evaluation confirms improved revision usefulness but identifies a remaining gap in technical accuracy.

Hugging Face daily papers · 9d agoAI research

DynSHAP: Towards Explainable Dynamic Survival Analysis

DynSHAP extends SHAP explainability to dynamic survival analysis, treating time-feature pairs as Shapley players for longitudinal clinical predictions.

DynSHAP adapts marginal SHAP estimators to dynamic survival analysis by treating time-feature pairs as players in the Shapley game, handling longitudinal irregular inputs and functional survival outputs. Temporal DynSHAP learns linear feature dependencies over time and addresses them with conditional sampling. On synthetic data with ground-truth attributions it recovers temporally dependent features more accurately than marginal estimators, and it produces faithful attributions on two real-world clinical datasets across two DSA architectures.

arXiv cs.AI / cs.LG / cs.CL · 5d agoAI research

What We Learned by Reproducing 2,200 papers from ICML

Hugging Face shares lessons from openly reproducing 2,200 ICML 2026 papers, examining reproducibility and open implementation practices in machine learning research.

Hugging Face published a retrospective on its open reproduction effort covering 2,200 papers from ICML 2026. The post summarizes lessons learned about reproducibility and building open, community-driven implementations of published machine learning research. No detailed article text was available in the feed.

Hugging Face Blog · Aug 13, 2026AI research

Better answers, broader thinking: What students gain from ChatGPT and critical-thinking training

OpenAI published a randomized study of over 1,000 students examining ChatGPT's effects on critical thinking and performance.

OpenAI released results from a randomized study of more than 1,000 students using ChatGPT on a real-world university assignment. The research examined effects on critical thinking, originality, and student performance. Findings inform ongoing debates about AI's role in education and learning outcomes.

OpenAI News · 20d agoAI research

Emergency Department Revisit Quality Review Screening: Exploring Human Decision-Making and Artificial Intelligence Support

A retrospective study found GPT-4 over-flagged emergency department revisit cases while an LLM knowledge-graph screener achieved 83-100% positive predictive value.

In an exploratory retrospective study of 99 emergency department diagnosis pairs from a multihospital health system, clinicians and GPT-4 independently judged whether revisit pairs warranted further assessment. GPT-4 responses correlated poorly with clinicians, flagging 94% of pairs for follow-up, 4.4-13.3 times more than clinicians, though prompt engineering was minimal. An algorithm leveraging an LLM-populated knowledge graph (KGA) achieved 83-100% positive predictive value against at least one clinician rater, suggesting LLM-based screening could broaden revisit quality review without substantially increasing reviewer workload.

arXiv cs.AI / cs.LG / cs.CL · 7d agoAI research1

Unified CT and MRI Pancreas Segmentation for Label-Efficient Cross-Modality Subregion Transfer

Domain-adversarial nnU-Net trained on 4,604 CT/MRI scans achieves 87.31% Dice pancreas segmentation with label-efficient subregion transfer.

A unified 3D pancreas segmentation framework applies domain-adversarial learning to 4,604 heterogeneous CT and MRI scans, aligning CT-MRI features via a latent domain discriminator on a shared nnU-Net encoder-decoder. Whole-pancreas segmentation reaches 87.31% Dice in-distribution and 84.20%-88.09% across external OOD datasets. The transferred encoder achieves 80.53% Dice on MRI and 83.05% on CT for downstream head-body-tail subregion segmentation using only limited MRI subregion annotations.

arXiv cs.AI / cs.LG / cs.CL · 5d agoAI research