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Rust Supply Chain Attack Puts Build-Time Malware in Crates with 245 Million Downloads

Compromised maintainer account published malicious versions of popular Rust crates with 245M downloads, delivering a build-time payload via typosquatted proc-macro1 dependency.

The Rust Project deleted malicious releases of arrayref 0.3.10, internment 0.8.7, and append-only-vec 0.1.9 from crates.io after a compromised maintainer account added a typosquatted dependency, proc-macro1, whose build script downloaded and executed a remote payload during compilation. Each malicious version was online for 86 to 107 minutes on August 20, 2026, before deletion. The build script disabled TLS validation and deployed OS-specific implants on Unix, macOS, and Windows, with builds alone sufficient to trigger execution. Wiz Research confirmed active exploitation, noting the impacted packages appear in 35% of cloud and code environments and over 75% of Rust-using environments; arrayref alone has 245 million all-time downloads and 403 dependent crates.

The Hacker News·Aug 25, 16:13 UTC · 22d agoMalware in the wild1

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Evaluating Time-Series Foundation Models and Multimodal Dietary Context for CGM Forecasting

Study finds zero-shot time-series foundation models underperform on CGM forecasting; fine-tuned Chronos-Bolt cuts RMSE up to 18.4% and dietary context adds signal.

The paper evaluates time-series foundation models for continuous glucose monitoring forecasting across eight public datasets covering Type 1 diabetes, Type 2 diabetes, and non-diabetes populations. Under a unified protocol, zero-shot foundation models did not consistently outperform baselines like Elastic Net and PatchTST, but lightweight fine-tuning did, with fine-tuned Chronos-Bolt reducing RMSE by 6.5%-18.4% in the T1D cohort and 8.6%-18.2% in the non-diabetes/T2D cohort. A residual-based fusion framework adding dietary context from CGMacros reduced overall RMSE by about 3% and postprandial RMSE by about 15% versus CGM-only baselines.

arXiv cs.AI / cs.LG / cs.CL·Sep 10, 17:43 UTC · 6d agoAI research

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14 Trojanized npm Packages Drop RedC2 4.0 Linux Backdoor With AI

Trend Micro found 14 trojanized npm calendar utilities delivering RedC2 4.0, an AI-powered cross-platform backdoor sold for $99.99.

Trend Micro's TrendAI identified 14 functional but trojanized npm packages (streak-*, kit-map-vim, map-streak-kit) that load a bundled Linux implant, the RedShell beacon of RedC2 4.0, without requiring install hooks. RedC2 4.0, sold by Red Offsec for $99.99 and advertised on Hack Forums by actor MarlboroMan in June 2026, offers shell access, credential theft, SOCKS5 proxying, in-memory execution, and an LLM-driven component called Red Agent for natural-language post-exploitation. The framework has evolved from version 2.0 in August 2025 through 4.0, with the Linux beacon introduced in the latest release.

The Hacker News·Aug 24, 17:23 UTC · 23d agoMalware in the wild

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Ambient @ EgoProactive 2026 : Proactive Egocentric Assistance with Visually Grounded Supervision

ECCV 2026 challenge winner reformulates egocentric intervention timing as single-token classification, boosting macro-F1 by 0.249 over free-form generation.

The paper describes the winning submission to the EgoProactive track of the ECCV 2026 Wearable AI Challenge, ranking first in the large-model division and second in the <=2B division. The method reformulates intervention timing as single-token yes/no classification, improving macro-F1 by 0.249 and G-mean by 0.30 over free-form generation. Supervision generated by a tool-calling video agent transferred better than a narration-only dataset that was four times larger and ten times cheaper, suggesting visual grounding matters more than annotation volume.

Hugging Face daily papers·Sep 9, 20:00 UTC · 7d agoAI research

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Cross-Model Agreement as a Deployment-Time Reliability Signal for Automatic Polyp Segmentation

Referee-Based Quality Estimation flags unreliable polyp segmentations at inference without ground truth, reaching ROC-AUC 0.960 with SegFormer-B0 referees.

RBQE measures agreement between a primary segmentation model and an independently trained referee on a 1,223-image external benchmark drawn from four public datasets. A cross-architecture SegFormer-B0 referee achieves the strongest signal (ROC-AUC 0.960), beating a Test-Time Augmentation baseline by 0.055 ROC-AUC under an identical protocol. Excluding trivially separable empty-mask cases, ROC-AUC falls to 0.876 (SegFormer-B0) and 0.783 (same-architecture control), but RBQE's margin over baselines widens. Progressive rejection of low-agreement predictions increases mean Dice of retained outputs, supporting selective prediction at the cost of one extra forward pass.

arXiv cs.AI / cs.LG / cs.CL·Sep 9, 17:32 UTC · 7d agoAI research

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Testing race conditions with memory access tracing and stack-based delay injection

Google Project Zero released MAccConc, Linux kernel tooling that traces memory accesses to explore and test race condition interleavings.

A Google Project Zero researcher published MAccConc (Memory Access Concurrency), tooling for exploring possible interleavings of multithreaded test cases in the Linux kernel, available on GitHub. The tools use KCOV with ASAN outline-mode instrumentation to record per-access memory traces, enabling automatic testing of all A-B-A interleavings plus terminal and GUI explorers for manual analysis. The work targets confirming race condition candidates, building reliable regression tests, and enabling concurrency fuzzing, drawing on ideas from SKI and Ned Williamson's sockfuzzer.

Google Project Zero·Sep 8, 07:00 UTC · 8d agoResearch1

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NVIDIA Details BioNeMo Inference Runtime (BioIR): 2.90x Higher Boltz-2 Folding Throughput and 58.5K Residues per GPU-Hour on 8xH100

NVIDIA released BioNeMo Inference Runtime (BioIR), an open-source PyTorch-compatible library delivering 2.90x higher Boltz-2 protein-folding throughput on 8xH100 GPUs.

NVIDIA detailed BioIR, a Python library that accelerates Boltz-2, OpenFold2, and OpenFold3 structure-prediction inference on NVIDIA GPUs while preserving standard PyTorch workflows. On a matched benchmark of 1,000 human dimers on 8xH100 80GB GPUs, BioIR delivered 58.5K folded residues per GPU-hour versus 20.2K for a torch.compile baseline, a 2.90x throughput gain. BioIR already powered the AlphaFold Database expansion, generating about 31 million candidate complexes across 4,777 proteomes, with 1.81 million released as high-confidence predictions. Extrapolated to 1 million targets, estimated folding energy drops from 35 MWh to 11 MWh at 8-GPU TDP equivalents.

MarkTechPost·Sep 10, 21:57 UTC · 6d agoAI tools & infra1

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Perplexity Details Its GPU Embedding Stack: How Ivy, Tulip and ROSE Serve pplx-embed

Perplexity details its GPU embedding serving stack (Ivy, Tulip, ROSE), which reuses LLM prefill/decode kernels, CUDA graphs, and LazyTensors to cut launch overhead.

Perplexity engineers published a deep dive on the serving infrastructure behind pplx-embed, used across Perplexity Search and its API platform. The stack comprises Ivy (Rust HTTP gateway), Tulip (gRPC scheduling and batching), and ROSE (Runtime-Optimized Serving Engine), which reuses LLM prefill and decode kernels rather than running a separate embedding engine. Optimizations include whole-model CUDA graphs with lazy capture and a LazyTensor abstraction that overlaps CPU batch preparation with in-flight GPU work. Benchmarks are reported against vLLM v0.22.0 in BF16, with FlashAttention 4 generally fastest but FlashInfer 3 winning on Qwen-based models at very long sequence lengths.

MarkTechPost·Sep 6, 03:20 UTC · 10d agoAI tools & infra1

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Embedded Graph Flows for Categorical Graph Generation

Researchers propose Embedded Graph Flows, a generative model with learned categorical embeddings that beats DiGress and GruM on molecular graph benchmarks.

Embedded Graph Flows (EGF) learns continuous embeddings for node and unordered-edge categories and transports Gaussian noise toward these endpoints using a permutation-equivariant graph transformer. On QM9 it achieves the best result on all four reported metrics, with a Fréchet ChemNet Distance of 0.150 versus 0.717 for DiGress and 0.812 for GruM. On ZINC250k it retains the lowest NSPDK MMD, indicating close agreement with local substructures of reference molecules. Code is released on GitHub.

arXiv cs.AI / cs.LG / cs.CL·Sep 4, 16:26 UTC · 12d agoAI research1

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Right Tool, Right Job: Native-Language Evaluation, Tokenizer Sensitivity, and Methodological Findings from a French-Only BabyLM

French BabyLM entry METRON-FR (125M GPT-2, 92.47M words) shows tokenizer artifacts dominate child-scale zero-shot evaluation; proposes standard diagnostics.

METRON-FR is a 125M-parameter GPT-2 pretrained on 92.47M French words, submitted to the BabyLM 2026 Strict track, scoring 85.97% on the native Quebec-French QFrBLiMP benchmark and 62.80% on the BabyLM-weighted leaderboard. A cross-lingual GLUE protocol combining French task-data translation with rank-16 LoRA shows relational tasks gain while world-knowledge tasks regress. Bilingual Lexicon Induction reaches p@1 of 68.84%, 18x above chance, and ablations show single-token zero-shot scoring is dominated by tokenizer and template artifacts at child scale.

arXiv cs.AI / cs.LG / cs.CL·Sep 15, 16:43 UTC · 1d agoAI research

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How Does mHC Use Its Residual Streams? Selective Routing and Near-Identity Mixing

Analysis of DeepSeek-V4-Flash shows four-stream mHC residual blocks use only about two streams effectively, with late-layer mixing providing little benefit.

The study examines the four-stream residual pathway of DeepSeek-V4-Flash, finding typical attention or FFN sites effectively use about two streams and that residual mixing is modest, occurring primarily in early layers. Replacing late mixers with identity increases C4 perplexity by only 1.9% while replacing early mixers raises it by 41%. Retaining the three largest routing weights per token increases perplexity by at most 2.7%, showing the model uses only part of the flexibility afforded by the four-stream design.

arXiv cs.AI / cs.LG / cs.CL·Sep 4, 16:02 UTC · 12d agoAI research

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Convergent Emergence of In-Context Learning Across Modalities

Controlled experiments show few-shot in-context learning emerges across six modalities including language, genomes, images, and proteins, partially supporting a convergence hypothesis.

The paper tests the Convergent Emergence Hypothesis: that few-shot in-context learning, when it emerges, shares a common cross-modality difficulty profile. A controlled framework instantiated the same task suite across six modalities: language, genome, integer sequences, time series, images, and proteins. Paired-mapping ICL emerged in all six modalities, surpassed controlled baselines, and showed correlated per-task effects in five of them, providing partial support for the hypothesis.

Hugging Face daily papers·Sep 11, 20:00 UTC · 5d agoAI research

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Knowing What Not to Answer: Selective Non-Compliance in Vision-Language Models

Researchers introduce KoNA, a benchmark exposing vision-language models' failures at selective non-compliance, plus fine-tuning that improves refusal and abstention accuracy.

KoNA is a benchmark for evaluating selective non-compliance in vision-language models across five categories: False Premise, Visual Inaccessibility, Universal Unknown, Task Feasibility and Safety. It tests both query-level and component-level non-compliance using paired single and compound queries, and evaluations across diverse VLMs show models often fail to refuse, correct or abstain appropriately, with failures worsening on compound queries. Fine-tuning VLMs on KoNA examples substantially improves non-compliance accuracy while largely maintaining performance on fully answerable tasks.

Hugging Face daily papers·Sep 3, 20:00 UTC · 13d agoAI research1

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Augustinian BabyLM: What Ostensive Definition Can and Cannot Teach a Small Language Model

Study shows visually grounded token embeddings in a small masked LM persist through training and improve object-property knowledge, but escape standard BabyLM benchmarks.

The paper implements ostensive definition for a small DeBERTa masked language model trained on 10M words, seeding visually grounded tokens with embeddings derived from labeled image regions before training. Visual initialization leaves a persistent, seed-replicated advantage on object-property knowledge (COMPS) and a corpus-tailored Visual-Property Swap benchmark covering color, material, size, and shape, but has no effect on most BabyLM grammar benchmarks. Synthetic grounding of previously unseeded words causally transfers the advantage to exactly those words.

arXiv cs.AI / cs.LG / cs.CL·Sep 10, 17:43 UTC · 6d agoAI research

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AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

Google DeepMind released AlphaGenome Atlas, a free 1-petabyte platform predicting the molecular effects of all ~9 billion possible single-letter DNA variants.

Google DeepMind introduced AlphaGenome Atlas, containing precomputed predictions for the effects of roughly 9 billion single-nucleotide variants across the human genome, spanning hundreds of human and mouse cell types. The 1-petabyte dataset is more than 30 times larger than the AlphaFold Database and includes an AlphaGenome Variant Impact (AVI) score combining AlphaGenome and AlphaMissense predictions for both coding and non-coding regions. External collaborators have already used it to identify and experimentally verify variants in unsolved rare disease research. It is available via a free web portal, the AlphaGenome API, and as a skill in Google Antigravity.

Google DeepMind·Sep 8, 14:00 UTC · 8d agoAI research 2 sources

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Model-Aware Schedules Improve Generation via Fiberwise Optimal Transport

Researchers introduce model-aware diffusion schedules via fiberwise optimal transport, cutting flow-matching FID on CIFAR-10 by 38.6% at 16 function evaluations.

The paper proposes constructing diffusion and flow-matching sampling schedules from a fiberwise prediction risk defined via optimal transport, combined with coefficient-path kinetic action, yielding a closed-form time allocation. Across DDPM and flow-matching experiments spanning targets, datasets, and architectures, the schedules beat model-agnostic baselines, including a 38.6% relative FID reduction for flow matching on CIFAR-10 at 16 function evaluations. Normalized fiberwise-risk profiles from independently trained models align closely, suggesting empirical universality, and a frozen analytic allocation template retains most of the gains.

arXiv cs.AI / cs.LG / cs.CL·Sep 10, 17:30 UTC · 6d agoAI research

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Molecular Déjà Vu: Digit-Level Retrieval of Published Values in Frontier Language Models

Audit of 22 frontier models finds widespread verbatim retrieval of published molecular property values, with higher reasoning increasing recall of memorized numbers.

An arXiv audit tests 22 frontier LLMs across 12 molecular regression benchmarks for verbatim retrieval of published values. More than 50% of the LLMs show verbatim retrieval on five datasets, and identical experiments are flagged 89% more often at a high reasoning level than at the lowest one. Suppressing retrieval moves model prediction errors closer together in relative terms, suggesting predictive capability is not determined solely by memorized values.

arXiv cs.AI / cs.LG / cs.CL·Sep 4, 17:32 UTC · 12d agoAI research1

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Studying Image Tokenizers as Visual Languages in Unified Multimodal Models

A controlled pure-autoregressive testbed shows task-specific validation losses rank image tokenizers differently, with I2T loss the most consistent signal.

Researchers built a controlled pure-autoregressive testbed and tracked task-specific validation losses during multimodal continual pretraining across text, image, text-to-image (T2I), and image-to-text (I2T) prediction. They find losses should be analyzed per task because they exhibit distinct scaling behavior and rank tokenizers differently, and that the loss-performance relationship depends on the predicted token space. I2T loss, computed over a shared text vocabulary, correlates consistently with both generation and visual understanding performance after supervised finetuning. Case studies revisit the discriminator, semantic supervision, and vocabulary size as tokenizer design axes.

arXiv cs.AI / cs.LG / cs.CL·Sep 8, 17:57 UTC · 8d agoAI research1

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K-Bench: a clinically calibrated benchmark for evaluating large language models in high-risk mental health conversations

Clinician-calibrated K-Bench evaluates 125 LLM configurations on 200 high-risk mental health vignettes, exposing wide variation in suicide and violence risk handling.

K-Bench is a clinician-calibrated, protected benchmark evaluating 125 model configurations from 33 base models across 14 providers on 200 multi-turn vignettes covering suicide, self-harm, domestic violence, substance misuse and no-risk presentations. A frozen GPT-4o judge achieved 94.2% exact agreement with clinician consensus across 6,751 eligible comparisons from 151 clinician-rated transcripts. Leading models combined supportive conversation with combined-risk scores above 95, while risk exploration varied substantially among weaker configurations; therapeutic prompting helped weaker models and elevated reasoning produced no average improvement. A continuously updated public leaderboard is hosted at k-bench.ai with protected test materials.

arXiv cs.AI / cs.LG / cs.CL·Sep 14, 16:49 UTC · 2d agoAI safety & security

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OPEN-1B: A Fully Auditable Training Run

Open-1B releases a 1B-parameter model with bitwise-reproducible training, letting independent auditors verify every step of the run on commodity hardware.

The paper introduces a 'fully auditable' tier of model transparency: every training operation is reproducible with bitwise certainty on heterogeneous commodity hardware by imposing definite ordering on GPU kernel reductions, data batch ordering, and collective communication. Because replaying a full run on one machine is infeasible, a collective verification scheme lets many independent auditors certify individual steps covering the whole run. The authors release Open-1B with its full pretraining dataset, every intermediate checkpoint, the training codebase, and an audit harness. This rules out undisclosed data, injected biases, or backdoors that proof-of-learning or proof-of-training-data techniques cannot exclude.

arXiv cs.AI / cs.LG / cs.CL·Sep 15, 16:23 UTC · 1d agoAI research

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Reference-Based Bias Detection in LLMs via Relative Representations of Hidden States

Researchers propose auditing LLM bias via relative hidden-state representations, detecting bias increases with 3-50x less compute than output-level benchmarks.

The paper introduces a reference-based bias auditing method that compares hidden-state representations across model variants, such as before and after fine-tuning, by encoding sentences relative to a fixed anchor set. The resulting Representational Bias Shift (Delta-B) correlates with output-level bias change in 15 of 18 tested settings, reaching |r| = 0.84 under full fine-tuning across WildGuardMix, DecodingTrust, and ToxiGen benchmarks. Thresholding Delta-B detects checkpoints whose bias increased with ROC AUC between 0.65 and 0.99 and beats a SEAT-based baseline, while auditing a model in about three minutes with 3-50x less compute.

Hugging Face daily papers·Sep 8, 20:00 UTC · 8d agoAI research1

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Lightweight Vision Transformer Compression for On-Device Plant Disease Detection in Resource-Constrained Agricultural Field Conditions

A unified ViT compression pipeline (H-BAC pruning, quantization, distillation) cuts plant-disease models 54.5x to 6.01 MB while keeping 95.13% accuracy.

Researchers combined Hessian-Balanced Adaptive Block Pruning (H-BAC), guided by second-order sensitivity estimation, with quantization and attention-based knowledge distillation to compress Vision Transformers for on-device chilli plant disease detection in India. On a 3-class cross-village, cross-device out-of-distribution dataset, the integrated pipeline reduced model size from 327.42 MB to 6.01 MB (54.5x) at 95.13 +/- 2.32% accuracy, matching the 95.13% FP32 baseline. Ablations also show a directly trained 6.01 MB INT8 student reaches 94.87% accuracy, indicating where pruning and distillation add limited value.

arXiv cs.AI / cs.LG / cs.CL·Sep 4, 16:40 UTC · 12d agoAI research

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CoVeR: Coverage-Based Token Pruning for Multi-View 3D Reasoning in VLMs

CoVeR, a training-free coverage-based token pruner, preserves 93.5% of VLM 3D-reasoning performance using only about 8% of visual tokens.

Researchers introduce CoVeR, a deterministic, training-free selector that chooses visual tokens to cover every region of a multi-view 3D scene using only token coordinates. Unlike learned-importance and voxelization pruners, it enforces an exact per-scene token budget, avoids saturation plateaus, and prevents near-duplicate selections. Experiments across four vision-language models show it surpasses prior state of the art by 3.9 percentage points on average across three 3D reasoning benchmarks.

Hugging Face daily papers·Sep 7, 20:00 UTC · 9d agoAI research

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Target leakage, not model class, explains reported accuracy in survey-based cardiovascular screening: a leakage-tiered audit of glass-box and tabular foundation models

Audits of 10 classifiers on BRFSS show target leakage, not model class, drives the reported 0.89 AUROC in survey-based cardiovascular screening.

The study benchmarks ten model classes, including glass-box and tabular foundation models, for prevalent myocardial infarction on 442,067 respondents of the 2022 BRFSS across five feature tiers of decreasing leakage risk. Removing two post-diagnostic features costs every model 0.049-0.051 AUROC and collapses performance into a 0.0045-wide band, and the explainable boosting machine matches all alternatives within 0.005 while scoring roughly 104x faster than the strongest foundation model. Frozen models transport within 0.002 AUROC to 2023 data; the authors conclude evaluation practice and feature sets, not model capacity, are the binding constraint.

arXiv cs.AI / cs.LG / cs.CL·Sep 10, 17:29 UTC · 6d agoAI research1

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Prolific Microsoft 0-day hunter drops CrowdStrike Falcon exploit PoC

Researcher Nightmare Eclipse released a PoC for FalconFlank, a privilege escalation zero-day in CrowdStrike Falcon's Office macro remediation feature.

Researcher Nightmare Eclipse published a zero-day PoC dubbed FalconFlank targeting CrowdStrike Falcon's Microsoft Office malicious macro removal feature, achieving privilege escalation on fully updated Windows 11 25H2 and Windows Server 2025 with Optimal Protection and macro removal enabled. Kevin Beaumont independently confirmed the exploit works. The same researcher also released HardBreacher, an elevation-of-privilege bug in Kaspersky Endpoint (since fixed via update), PrettyPrague, an Avast Sandbox flaw that dumps the SAM database for a SYSTEM shell (Gen Digital is developing a patch), and GreenSection, an Nvidia memory corruption bug that crashes systems. CrowdStrike advises customers to disable the Suspicious Macro Removal Windows policy while it investigates.

The Register · Security·Sep 3, 18:08 UTC · 13d agoExploit / PoC

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Deepmind's AlphaGenome Atlas maps every possible DNA change in the human genome

DeepMind's AlphaGenome Atlas precomputes impact predictions for ~9 billion human DNA variants in a 1-petabyte dataset; its AVI score beats CADD in benchmarks

Google DeepMind released the AlphaGenome Atlas, precomputing functional-effect predictions for roughly 9 billion human genome variants (about 27,000 prediction values per variant) in a one-petabyte dataset more than 30 times the size of the AlphaFold database. The accompanying AlphaGenome Variant Impact Score (AVI), a small neural network combining AlphaGenome, AlphaMissense and evolutionary conservation features (18 inputs versus CADD's 150+), outperformed existing tools on clinically classified variants, ranking causal variants in the top 50 candidates for 29.5% of solved GREGoR cases versus 12.5% for CADD. A GREGoR epilepsy case illustrates the impact: AVI elevated a previously unclear DNM1 splice variant that lab experiments confirmed as likely disease-causing. The atlas is available for noncommercial use via web portal, API and a Google Antigravity skill, with a commercial version planned through Google Cloud.

The Decoder·Sep 9, 13:40 UTC · 7d agoAI research

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CARDEA: Auditable Reasoning Grounded in Spatial Evidence for End-to-End Coronary Angiography Interpretation

CARDEA, a vision-language model trained only on public data, matches cardiologists on coronary angiography complexity assessment while exposing auditable bounding-box evidence.

CARDEA is a unified large vision-language model serving as the inference core of an end-to-end coronary angiography pipeline from multi-view videos to study-level diagnosis. It was trained on public datasets through visual alignment, self-distilled Chain-of-Box cold start, and reinforcement learning with verifiable rewards encouraging bounding-box reasoning. It reached 0.91 accuracy on dominance classification under domain shift and 0.90 on complexity assessment, comparable to two interventional cardiologists. RLVR raised zero-shot report generation vessel-severity macro-F1 from 0.513 to 0.686, while supervised imitation alone did not.

Hugging Face daily papers·Sep 6, 20:00 UTC · 10d agoAI research

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NCP-ArchPreview Technical Report: Moving towards Latent Space Language Models through Next Concept Prediction

An 8.9B-parameter latent-space language model using next-concept prediction matches OLMo-3-7B pretraining loss with only 51.3% of the training tokens.

NCP-ArchPreview augments next-token prediction with Next Concept Prediction over a product-quantized concept vocabulary built from hidden states, trained jointly end-to-end. The 8.9B model was trained on 5.73T tokens from the Dolma-3 dataset, the largest latent-space language model demonstration to date. It consumes 51.3% of the tokens to reach OLMo-3-7B's final pretraining loss and outperforms it by 2.45 points on the downstream macro-average, including a 5.99-point GSM8K gain. The learned latent space also enables lightweight domain adaptation via a 17M-parameter VQ module and improves speculative drafting accepted length by 4.17%.

Hugging Face daily papers·Sep 8, 20:00 UTC · 8d agoAI research1

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Google DeepMind Releases AlphaGenome Atlas With Precomputed Molecular Effect Predictions and AVI Scores for 9 Billion Human DNA Variants

Google DeepMind launched AlphaGenome Atlas, precomputing molecular effect predictions and AVI impact scores for ~9 billion human single-nucleotide variants in a 1-petabyte catalogue.

Google DeepMind released AlphaGenome Atlas, a 1-petabyte catalogue of precomputed molecular effect predictions for roughly 9 billion possible single-nucleotide variants in the human genome. It introduces the AlphaGenome Variant Impact (AVI) score, combining AlphaGenome regulatory predictions with AlphaMissense, plus per-variant feature attributions and over 2,500 recurrent DNA sequence motifs. DeepMind reports best-in-class AVI performance on variant pathogenicity and rare disease benchmarks. Early users at the Broad Institute, University of Exeter, and Stowers Institute demonstrated rare-disease variant reprioritization and 22% more non-coding associations across 54,000+ UK Biobank genomes.

MarkTechPost·Sep 8, 19:00 UTC · 8d agoAI research2

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Pre-Whitening and BCJR Posterior Distillation for Bi-LSTM Detection in Faster-than-Nyquist Signaling

Study shows nested-window Bi-LSTM architectures do not improve faster-than-Nyquist detection; pre-whitening plus BCJR distillation cuts bit error rates.

Across roughly 260 controlled trainings, processing nested intersymbol-interference windows in separate recurrent branches never significantly beat a plain Bi-LSTM at matched parameter budgets. The authors attribute the limitation to the observation model rather than architecture, and instead pre-whiten inputs and distill BCJR soft posteriors into the network. With 3.4% more parameters, the method reaches 1.05x the BCJR bit error rate at compression factor 0.8 and 1.89x at 0.7, improving to 1.47x with a wider whitened window.

arXiv cs.AI / cs.LG / cs.CL·Sep 7, 17:07 UTC · 9d agoAI research

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DynSHAP: Towards Explainable Dynamic Survival Analysis

DynSHAP extends SHAP explainability to dynamic survival analysis, treating time-feature pairs as Shapley players for longitudinal clinical predictions.

DynSHAP adapts marginal SHAP estimators to dynamic survival analysis by treating time-feature pairs as players in the Shapley game, handling longitudinal irregular inputs and functional survival outputs. Temporal DynSHAP learns linear feature dependencies over time and addresses them with conditional sampling. On synthetic data with ground-truth attributions it recovers temporally dependent features more accurately than marginal estimators, and it produces faithful attributions on two real-world clinical datasets across two DSA architectures.

arXiv cs.AI / cs.LG / cs.CL·Sep 11, 16:39 UTC · 5d agoAI research

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27.5KB language-agnostic WebGPU syntax highlighter

A developer released gpu-lexer, a 27.5KB language-agnostic syntax highlighter that uses a tiny WebGPU model to label code tokens in the browser.

gpu-lexer splits source into words, whitespace, and symbols, then a small WebGPU model uses local and whole-file context to assign nine token classes, working on languages never seen in training. On held-out files, 12.57% of token labels differ from Shiki, though this measures agreement with Shiki rather than objective correctness. In benchmarks against Shiki 4.4.3, Prism.js, Highlight.js, Sugar High, and Starry Night, it highlighted 10 concatenated copies of three.min.js (5.56M characters) about 10x faster on an Apple M4 Pro in Chrome 152. The author frames it as an experiment, not a grammar-equivalent highlighter.

Hacker News · security·Sep 9, 01:14 UTC · 7d agoAI tools & infraHN 21↑ · 5 comments1

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