Pyrite benchmarks LLM agents on protein-ligand pose ranking
On 1,500 pose pairs, PyriteFeaturizer reaches 74% accuracy and PyriteReasoner 67%, while expert chemists perform near chance.
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Stories tagged #drug-discovery
Drugmaker CEOs skeptical of AI disease cure claims
Pharmaceutical executives question Silicon Valley's promises that AI will cure diseases.
Google Antigravity accelerates drug discovery with AI
Google Antigravity uses cheminformatics skills to propose novel lung cancer molecules in one hour.
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TACFormer generates full PROTACs conditioned on target protein sequences
A GPT-style decoder uses ESM-2 embeddings of the protein of interest instead of designing only the linker.
Anthropic says Claude aided early drug work with six partners
Reported lab results include a CAR-T design about 70% shorter and about 35,000 antibody designs.
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Claude fails to create scorpion antivenom drug
Anthropic Claude generated protein binders for scorpion venom toxins but did not produce functional antivenom.
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OpenAI acquires Orchestra Bio for drug-development AI agents
Orchestra will fold into Rosalind; terms were not disclosed, and OpenAI already works with Novo Nordisk and Moderna.
OpenAI acquires Orchestra Bio for its Rosalind life-sciences work
Terms were undisclosed; the four-year-old startup had reportedly raised about $20 million by 2025.
Claude designed lab-tested binders against scorpion neurotoxins
Of 211 designs tested by two CROs, 17 met binding criteria; cellular neutralization was not confirmed.
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DrugHarness couples skill evolution with computational drug discovery agents
Without evolution it beats reported MolClaw-CC affinity accuracy by 10.8 points; a compound hit 14.19 nM IC50.
Accelerating the search for antimicrobial peptides with Google Antigravity
DeepMind used Antigravity and ProtNLM to prioritize a novel antimicrobial peptide now entering wet-lab validation.
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Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio
Leash Bio’s Ian Quigley discusses DNA-encoded library data and the new Minos dataset for scientific agents.
Zuckerberg's Biohub leads a $1.8 billion push to build AI models that predict cell behavior
Zuckerberg's Biohub is leading a $1.8 billion effort to build AI models that predict cell behavior.
DRIFT: Disentangled Responsive-Invariant Flow Transport for Single-Cell Perturbation Prediction
DRIFT predicts single-cell perturbation responses by flow-matching only a disentangled responsive cell-state block.
Foundries vs Navigators: Lowering the Cost of Science
A Latent Space essay argues AI cheapens scientific thinking while biotech foundries still gate physical experiments.
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Enveda secures $311M to bring more nature-derived AI drugs into clinical trials
Enveda raised a $311 million Series E at a $2 billion valuation to advance AI-discovered, nature-derived drugs into trials.
Anthropic’s biolab made a discovery it’s comparing to Crispr
Anthropic says Claude agents found a bacteriophage enzyme system it compares to CRISPR.
Inside Basecamp Research, the AI startup turning evolution into training data
AI startup Basecamp Research raised $140M from Nvidia and Anthropic to train biological AI models on massive novel genetic datasets for drug discovery.
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Anthropic is setting up a biology lab where Claude guides robots through drug experiments
Anthropic is building a San Francisco biology lab where Claude directs robots in physical drug experiments.
How a researcher uses Codex and ChatGPT to search for new antimicrobial molecules
OpenAI profiles César de la Fuente's lab using ChatGPT and Codex alongside deep-learning models to accelerate antimicrobial molecule discovery.
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