Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub
DeepMind and Biohub researchers say AlphaFold did not solve protein folding and biology needs better data, not just scale.
4 stories, newest first · one card per story
DeepMind and Biohub researchers say AlphaFold did not solve protein folding and biology needs better data, not just scale.
Graph Schrödinger bridges with state costs are solved exactly via a Feynman-Kac tilt, with no learning.
Fold2Reason post-trains language models on protein-structure QA, lifting reasoning across 10 benchmarks and raising macro-average accuracy from 45.09% to 48.33%.

NVIDIA released BioNeMo Inference Runtime (BioIR), an open-source PyTorch-compatible library delivering 2.90x higher Boltz-2 protein-folding throughput on 8xH100 GPUs.
Today 1.6K readers · 2.5K views · 779 reads · all time 189K views